1/50. dermatomyositis in association with transitional cell carcinoma of the bladder.We report a case of dermatomyositis occurring in association with transitional cell carcinoma of the bladder. The case illustrates the importance of a thorough search for neoplasms in elderly patients with dermatomyositis and is a reminder that bladder cancer may be a rare cause of dermatomyositis. The case also shows that successful treatment of an underlying tumour may lead to resolution of paraneoplastic dermatomyositis, and relapse of cutaneous and muscle symptoms and signs may indicate recurrence of tumour.- - - - - - - - - - ranking = 1keywords = cancer, neoplasm (Clic here for more details about this article) |
2/50. A case of Sweet's syndrome in patient with dermatomyositis.Sweet's syndrome (SS) has been reported as an association with malignant neoplasms and autoimmune diseases, e.g., Behcet's disease, sjogren's syndrome, and rheumatoid arthritis. But dermatomyositis (DM), one of the rare autoimmune diseases, was not reported as an associated disease of SS. We describe an interesting case of SS associated with DM. diagnosis was made by skin biopsy, and subsequent clinical resolution occurred after institution of prednisolone.- - - - - - - - - - ranking = 0.0025091366084203keywords = neoplasm (Clic here for more details about this article) |
3/50. Paraneoplastic amyopathic dermatomyositis associated with breast cancer recurrence.Amyopathic dermatomyositis, also known as dermatomyositis sine myositis, describes patients with the typical cutaneous features of dermatomyositis but without evidence of inflammatory myopathy. There have been 3 reported cases of amyopathic dermatomyositis associated with breast cancer in patients with no prior malignancy. We describe the first case of paraneoplastic amyopathic dermatomyositis associated with breast cancer recurrence.- - - - - - - - - - ranking = 5.9849451803495keywords = cancer (Clic here for more details about this article) |
4/50. dermatomyositis as a presenting symptom of ovarian cancer.BACKGROUND: Among gynecologic malignancies, the coexistence of ovarian cancer and dermatomyositis is most frequent. CASE: A 75-year-old woman presented with dermatomyositis, and a search for underlying malignancy found an otherwise asymptomatic ovarian carcinoma with para-aortic lymph node metastases. After resection and chemotherapy, the muscle weakness and skin lesions relating to dermatomyositis began to improve. CONCLUSION: dermatomyositis can be the only presenting symptom of ovarian cancer, so an evaluation for suspected underlying malignancy should be done.- - - - - - - - - - ranking = 5.9849451803495keywords = cancer (Clic here for more details about this article) |
5/50. dermatomyositis associated with malignancy. 12 case reports.dermatomyositis (DM) is an idiopathic inflammatory disease of unknown etiology which manifests itself with symmetrical proximal muscle weakness and typical heliotrope skin rash. Internal malignancy is a specific trigger for some cases of DM. The aim of this study is to find predictive signs of cancer in dermatomyositis patients. Twelve (2 males and 10 females) (24%) out of 50 adult patients with DM (10 males and 40 females between 21 and 81 years old) had associated with malignancy (paraneopastic dermatomyositis, PDM). The male: female ratio in patients with idiopathic dermatomyositis (IDM) was 1:3.75 and for PDM it was 1:5. The frequency of dermatomyositis increases with age. PDM is most frequent between 40 and 69 years of life. Associated malignancies were respiratory tract carcinomas in males, genital and breast carcinomas in females. DM preceded the carcinoma in 5 cases (41.7%); 7 patients (58.3%) had already been treated for malignancy. In conclusion PDM in our country is more frequent in females and in the age after 40 years. association of dermatomyositis with malignancy is relatively high.- - - - - - - - - - ranking = 0.99749086339158keywords = cancer (Clic here for more details about this article) |
6/50. dermatomyositis accompanied by rectal cancer: report of a case.dermatomyositis (DM) is a rare inflammatory disorder of the skin and muscles associated with an increased incidence of malignancy. We describe herein the case of a 59-year-old woman with DM accompanied by rectal cancer. Following excision of the rectal cancer, the characteristic features of the skin rash such as the heliotrope eyelid rash and Gottron's papules, and proximal muscle weakness, improved. Moreover, the elevated preoperative serum levels of muscle-associated enzymes, including aspartate transaminase, creatine phosphokinase, lactate dehydrogenase, and aldolase, decreased from 38 to 16 (IU/1), 138 to 42 (IU/1), 672 to 515 (IU/1), and 32.2 to 4.3 (IU/1), respectively. The current concepts of the correlation between DM and malignancy are discussed with regard to the present case.- - - - - - - - - - ranking = 5.9849451803495keywords = cancer (Clic here for more details about this article) |
7/50. Fatal bladder cancer and dermatomyositis.dermatomyositis is an uncommon inflammatory myopathy accompanied by characteristic cutaneous findings. adult-onset dermatomyositis is often associated with internal malignancy. We report a case of dermatomyositis associated with an aggressive and fatal case of transitional cell carcinoma of the bladder.- - - - - - - - - - ranking = 3.9899634535663keywords = cancer (Clic here for more details about this article) |
8/50. An unusual presentation of dermatomyositis: the type Wong variant revisited.We describe a 53-year-old white woman with dermatomyositis (DM) who had additional clinical findings of pityriasis rubra pilaris (type Wong dermatomyositis) with histopathologic features of both pityriasis rubra pilaris (PRP) and porokeratosis. Type Wong dermatomyositis was originally described in 11 patients by Wong in 1969 and has been reported in 5 additional patients. This is a rarely described phenomenon in which patients with DM develop cutaneous hyperkeratotic lesions that resemble PRP and histologically show follicular hyperkeratosis and hair follicle destruction. Arrector pilorum muscles also show degenerative findings and myositis. We believe that this is the first reported case of a patient with type Wong DM who also has clinical and histologic features suggestive of porokeratosis. This is important because of the association of adult-onset dermatomyositis with internal malignancy and the well-documented association of porokeratosis with immunosuppression. These clinical and histologic findings serve as markers for malignancy in patients with DM. These patients warrant a complete review of systems and investigation for age-appropriate neoplasms as well as close long-term follow-up by dermatologists to ensure that these cutaneous eruptions are not overlooked.- - - - - - - - - - ranking = 0.0025091366084203keywords = neoplasm (Clic here for more details about this article) |
9/50. Primary lung cancer associated with polymyositis/dermatomyositis, with a review of the literature.It has been suggested that lung cancer is frequently associated with polymyositis/dermatomyositis (PM/DM). The purpose of this study was to describe the clinical features of primary lung cancer associated with PM/DM. We first describe the clinical features of two cases treated in our hospital, and then provide a review of the literature. Finally, 24 patients (five females and 19 males) with primary lung cancer associated with PM/DM are retrospectively evaluated. Histological types of lung cancer were as follows: small cell lung cancer (n = 7), squamous cell carcinoma (n = 5), adenocarcinoma (n = 2), others (n = 5), and unknown (4). The onset of PM/DM is frequently observed before the detection of lung cancer. This is the first report to describe the clinical features of lung cancer associated with PM/DM.- - - - - - - - - - ranking = 10.972399497307keywords = cancer (Clic here for more details about this article) |
10/50. skin metastasis of breast cancer clinically undistinguished from amyopathic dermatomyositis.We report a 65-year-old woman who consulted us on May 25, 1998, showing pruritic, partially flagellate erythema on the back and upper extremities, livedo lesions with erythema on the loins, and erythematous papules on the dorsal finger joints for 2 months. Histopathological findings of erythema on the back showed mononuclear cell infiltration around capillaries and marked edema in the dermis. Laboratory data were within normal range except for positive anti-nuclear antibody. She had undergone total left mastectomy on June 2, 1997 for breast cancer. Supraclavicular lymph node metastasis was found at the beginning of May, 1998. A diagnosis of amyopathic dermatomyositis associated with breast cancer was made. erythema with itching gradually subsided from the end of August, 1998. Treatment with radiation and chemotherapy reduced lymph node swelling, but complete remission was not obtained. erythema similar to the previous lesion but without itching re-appeared on the back from January, 2000. Histological findings of erythema showed many carcinoma cells similar to the primary lesion of left breast cancer in the whole dermis. A diagnosis of skin metastasis of breast cancer was made. These findings suggest that skin metastasis should be taken into account for patients with erythema on the trunk similar to dermatomyositis.- - - - - - - - - - ranking = 7.9799269071326keywords = cancer (Clic here for more details about this article) |
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