1/3. Primary amebic meningoencephalitis with cerebral and cerebellar abscesses: case report.A case of fatal primary amebic meningoencephalitis is reported. We need to remind ourselves that, if the usual laboratory tests fail to show any microbial or fungal agents either in the CSF or in fluids or tissues obtained at operation, it is imperative that a warm wet slide preparation be made. Primary amebic meningoencephalitis is a very rare disease, and it is only by prompt recognition of the amebae that we can make an early diagnosis and institute the appropriate therapy.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |
2/3. Cerebral aspergillosis in immunologically competent patients.aspergillosis of the central nervous system is a rare disease, especially if the patient's immune system is not compromised. The authors report three cases of cerebral aspergillosis in the immunocompetent state: a rhinocerebral form in a diabetic patient, a direct extension from chronic aspergillus otitis media, and a postoperative aspergillus brain abscess after brain tumor surgery. In spite of the poor prognosis of cerebral aspergillosis, two of the patients survived. The pathogenesis, predisposing factors, radiologic findings including magnetic resonance image, and the outcome are presented. The pertinent literature of cerebral aspergillosis is also reviewed.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |
3/3. mucormycosis: experience with 10 patients.Rhinocerebral mucormycosis is a fulminating, devastating fungal disease, usually associated with debilitating diseases such as diabetes mellitus, leukaemia and immunosuppressive conditions. Ten patients with this rare disease have been treated over the past 14 years at the Beilinson Medical Centre. Nine patients had an underlying debilitating disease and one patient had latent diabetes mellitus which was diagnosed only after presentation of mucormycosis. Only two of the 10 patients survived. Early aggressive surgical debridement, together with amphotericin b and correction of underlying metabolic acidosis were found to be important factors associated with survival.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |