Cases reported "Diphtheria"

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1/8. 'Corynebacterium ulcerans': a potential cause of diphtheria.

    Symptoms similar to those of diphtheria may occasionally be caused by micro-organisms other than corynebacterium diphtheriae, such as zoonotic corynebacteria. A case of pharyngitis caused by toxigenic 'C. ulcerans' in a 9 year old girl illustrates the importance of including diphtheroids in the differential diagnosis. The presenting symptoms may have been attenuated by previous immunisation against C. diphtheriae. 'C. ulcerans' should be considered in the differential diagnosis of pharyngitis, especially in patients with a history of contact with farm animals or the consumption of raw dairy products.
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ranking = 1
keywords = ulcerans, ulcer
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2/8. infection of the skin caused by Corynebacterium ulcerans and mimicking classical cutaneous diphtheria.

    Extrapharyngeal infections caused by Corynebacterium ulcerans have rarely been reported previously, and diphtheria toxin production has usually not been addressed. This case demonstrates that strains of C. ulcerans that produce diphtheria toxin can cause infections of the skin that completely mimic typical cutaneous diphtheria, thereby potentially providing a source of bacteria capable of causing life-threatening diseases in the patient's environment. Therefore, it is recommended to screen wound swabs for coryneform bacteria, identify all isolates, carefully assess possible toxin production, and send questionable strains to a specialist or a reference laboratory.
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ranking = 1
keywords = ulcerans, ulcer
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3/8. Laryngopharyngitis by Corynebacterium ulcerans.

    A 71-year-old female patient was hospitalized with membranous laryngopharyngitis typical of classical diphtheria. A toxigenic strain of Corynebacterium ulcerans was isolated from the throat. The patient was treated for 6 days with amoxicillin-clavulanic acid and recovered without complications. This second reported case of diphtheric laryngopharyngitis caused by C. ulcerans in switzerland is a reminder that C. ulcerans should be included as a possible agent in patients with classical diphtheria symptoms.
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ranking = 1.1666666666667
keywords = ulcerans, ulcer
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4/8. Nasopharyngeal Corynebacterium ulcerans: a different diphtheria.

    A case of toxigenic Corynebacterium ulcerans infection is presented. The diagnosis was delayed and no anti-toxin administered. A nasopharyngeal biopsy was complicated by severe haemorrhage necessitating a post nasal pack. A brief review of the pathology and treatment of Corynebacterium ulcerans is given.
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ranking = 1
keywords = ulcerans, ulcer
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5/8. Corynebacterium ulcerans in an immunocompromised patient with diphtheria and her dog.

    Corynebacterium ulcerans causes zoonotic infections, such as diphtheria and extrapharyngeal infections. We report here the first case of a diphtheria-like illness caused by C. ulcerans in france and transmitted likely by a dog to an immunocompromised woman.
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ranking = 1
keywords = ulcerans, ulcer
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6/8. Diphtheria corneal ulcers.

    An adult with cutaneous diphtheria was admitted with bilateral purulent conjunctivitis and a perforated eye with most of the cornea absent due to corynebacterium diphtheriae. At the time of admission of grayish patch of corneal epithelium was noted in the other eye, and in the next 24 hours there developed a large corneal perforation with dissolution of much of the cornea. Involvement of the external eye in diphtheria is rare but it is usually associated with cutaneous forms of the disease. Cutaneous diphtheria has been prominent in several recent outbreaks in the united states. Prompt recognition, early antibiotic treatment, and neutralization of the toxin with antitoxin are required for successful therapy.
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ranking = 2.457951108884E-6
keywords = ulcer
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7/8. Cutaneous and pharyngeal diphtheria imported from the Indian subcontinent.

    We report the case of a 32-year-old woman who presented upon returning from India with cutaneous ulcers on the feet and pharyngitis. Microbiological testing showed the causative organism to be a toxigenic strain of corynebacterium diphtheriae. She was treated successfully with penicillin and diphtheria antitoxin. This case emphasises the importance of maintaining a high index of suspicion for such rare but significant infectious diseases.
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ranking = 6.14487777221E-7
keywords = ulcer
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8/8. Respiratory diphtheria caused by Corynebacterium ulcerans--Terre Haute, indiana, 1996.

    Diphtheria is a potentially severe illness; among unvaccinated persons, the case-fatality rate may be 5%-10%, even with appropriate treatment. During 1990-1995, approximately 4000 deaths resulted from the ongoing diphtheria epidemic in the former Soviet Union. In the united states, respiratory diphtheria is rare: during 1980-1995, only 41 cases were reported. Serologic studies in the 1970s and 1980s indicated that 20%-60% of U.S. adults aged > or = 20 years lacked immunity to diphtheria. This report describes a recent case of respiratory diphtheria caused by a toxin-producing strain of Corynebacterium ulcerans. The case occurred in a resident of indiana, and an investigation by public health authorities indicated that acquisition of the organism occurred locally in the state.
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ranking = 0.83333333333333
keywords = ulcerans, ulcer
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