Cases reported "Diseases in Twins"

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1/10. Median mental sinus in twins.

    Sinus on the chin can be the result of a chronic apical abscess due to pulp necrosis of a mandibular anterior tooth. The tooth is usually asymptomatic, and a dental cause is therefore not apparent to the patient or the unsuspecting clinician. Not infrequently, the patient may seek treatment from a dermatologist or general surgeon instead of a dentist. Excision and repair of the fistula may be carried out with subsequent breakdown because the dental pathology is not removed. This paper reports the presence of median mental sinus of dental origin in twins. One case healed following root canal therapy while the other required both root canal therapy and surgery to eliminate the infection.
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2/10. Microabrasion of teeth with discoloration resembling hypomaturation enamel defects: four-year follow up.

    Microabrasion with 18% HCl and pumice to remove enamel dysmineralization and improve esthetics is an accepted and effective treatment. This technique can probably be extended even to generalized defects resembling hypomaturation amelogenesis imperfecta that appear on all erupted teeth. Five children aged 9 to 11 with two types of enamel-hypomaturation probably due to developmental defects were treated successfully by microabrasion, with marked improvement of the discoloration. The patients were followed for up to four years. During this period, no tooth-sensitivity or staining was noted. The teeth looked healthier and shinier.
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3/10. Palatally displaced canine anomaly in monozygotic twins.

    The palatally displaced canine (PDC) anomaly is a tooth malposition occurring in 1% to 3% of most populations. From the results of family studies, the PDC phenotype appears to be under strong genetic influence. In this study we report monozygotic (MZ) twin girls with bilateral PDC expression. The finding of PDC anomaly in MZ twins--to our knowledge, the first such published case--lends further support to evidence of genetic control of the PDC anomaly.
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4/10. Mandibular buccal bifurcation cyst: enucleation without extraction.

    The mandibular buccal bifurcation cyst (MBBC) is a cystic lesion, which occurs on the buccal surface of the permanent mandibular first molar in children around 6-8 years old. Treatment of the cyst has been controversial: extraction of the involved tooth and enucleation of the cyst, or only enucleation, without extraction. The aim of this article is to familiarize oral and maxillofacial surgeons with this entity and the appropriate treatment approach. The diagnostic features of MBBC are described and the treatment approach in five patients with a total of seven cysts is presented. Two cases were identified in identical twins. Enucleation of the cyst without extraction of the involved tooth is the treatment of choice when the available data and experience in treating MBBC are considered.
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5/10. Resolution of furcation bone loss associated with vital pulp tissue after nonsurgical root canal treatment of three-rooted mandibular molars: a case report of identical twins.

    This case report demonstrates the simultaneous development of furcation bone loss in three-rooted tooth #30 with vital pulp tissue in identical twins. In the first report, resolution of furcal bone loss was seen after nonsurgical root canal treatment. In the second report, furcal bone loss resolved after non-surgical root canal treatment, and periodontal therapy reduced probing depths to maintainable levels.
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6/10. natal teeth in monozygotic twins with Van der Woude syndrome.

    The second monozygotic twin pair concordant for Van der Woude syndrome is reported. Clinical manifestations of this autosomal dominant clefting syndrome included bilateral lower lip pits, cleft lip, and cleft palate. Both sibs were found to have a natal tooth. No other cases of Van der Woude syndrome with this feature have been described previously. It is uncertain whether the presence of a natal tooth in this instance represents a low-frequency association of this disorder. However, it appears more likely that its occurrence was incidental, since natal teeth have been reported before in twin pairs as an isolated finding.
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7/10. Mandibular lateral incisor-canine transposition in monozygotic twins.

    Mandibular tooth transposition, involving the right lateral incisor and canine, is described in monozygotic twin girls. This report provides evidence suggesting that genetic factors influence the development of mandibular lateral incisor-canine (Mn.I2.C) transposition. Interceptive orthodontic treatment for children with this rare occlusal abnormality should be considered.
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8/10. Infraocclusion of primary molars in monozygotic twins: report of two cases.

    Genetic factors have been implicated in the aetiology of infraocclusion, but only three published reports describe infraocclusion of primary molars in twins. This case report describes the occurrence of infraocclusion in two pairs of twins. The distribution of affected teeth and the severity of infraocclusion were strikingly similar in each pair. The report provides further evidence of a genetic contribution to the aetiology of the condition, and also highlights the need to examine siblings, and especially twins, of children who present with an infraoccluded primary tooth.
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9/10. Comparison of craniofacial and dentoalveolar morphologies of three Japanese monozygotic twin pairs with cleft lip and/or palate discordancy.

    OBJECTIVE: In this study, we analyzed the craniofacial and dentoalveolar morphologies of three pairs of monozygotic twins discordant for cleft lip and/or palate (CL/P) in order to evaluate the effects of environmental factors on growth and development. DESIGN: Craniofacial and dentoalveolar morphologies revealed by analyses of cephalograms and dental casts were compared for each pair of twins discordant for CL/P. SUBJECTS: In case 1, the subjects were 10-year-old male twins, one of whom had a repaired unilateral cleft lip and alveolus and one of whom had an unrepaired unilateral cleft lip. In case 2, the subjects were 13-year-old female twins, one of whom had a repaired bilateral cleft lip and palate and one of whom had an unrepaired unilateral cleft lip. In case 3, the subjects were 9-year-old female twins, one of whom had a repaired unilateral cleft lip and palate and one of whom had no cleft. RESULTS: Cephalometric analysis disclosed distinguished intrapair differences in the maxillary and mandibular morphologies in cases 2 and 3. However, the tooth axes of the incisors in operated subjects were consistently influenced in all three cases. Dental cast analysis indicated that the shapes and sizes of the alveolar and dental arches in the operated subjects were affected in case 2 and, more severely, in case 3, while they looked fairly similar in case 1. CONCLUSIONS: Cephalometric and dental cast analyses demonstrated characteristic intrapair differences between the twins discordant for CL/P according to each cleft type. These morphological differences indicate that surgical closure of clefts may have considerable effects on craniofacial and dentoalveolar growth and development in CL/P patients.
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10/10. Hypodontia: genotype or environment? A case report of monozygotic twins.

    A case report is presented of monozygotic twins with variable expression of hypodontia. dna fingerprinting was used to confirm monozygosity, and this evidence supports the theory that genetic coding is not the sole controlling factor in tooth agenesis. It is suggested that dna fingerprinting should be considered the gold standard for determination of monozygosity.
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