1/68. diazepam in the treatment of tardive dyskinesia. Preliminary observations.Three patients, aged 23-33 years, with the diagnosis of schizophrenia, developed symptoms of tardive dyskinesia while receiving neuroleptic treatment, mostly with haloperidol. Existential problems and emotional upset seemed contributory. diazepam was found effective in controlling dyskinesia. Its therapeutic effect seemed not to be related to sedation. Some implications of the reported observations are mentioned.- - - - - - - - - - ranking = 1keywords = schizophrenia (Clic here for more details about this article) |
2/68. Two cases of risperidone-induced tardive dyskinesia and a review of the literature.Acase in which a 26 year old patient with undifferentiated schizophrenia, showing abnormal oral, lingual and jaw movements suggestive of tardive dyskinesia during a dose reduction of risperidone, is presented. A second case, relating to a 39 year old married woman diagnosed as having a DSM-IV schizophreniform disorder is also presented. These two cases are discussed in relation to the existing literature.- - - - - - - - - - ranking = 1keywords = schizophrenia (Clic here for more details about this article) |
3/68. risperidone implicated in the onset of tardive dyskinesia in a young woman.The aim of this case report is to highlight that risperidone may cause and ameliorate tardive dyskinesia. A 16 year old white women with a 12 month history of schizophrenia, developed buccolingual masticatory tardive dyskinesia after receiving risperidone 6 mg. She had received small dosages of typical antipsychotics before and during receiving risperidone for short periods. Recommencement of risperidone with 2 mg and increasing to 6 mg resulted in improvement in tardive dyskinesia and up until now she remains free of any abnormal involuntary movements.- - - - - - - - - - ranking = 1keywords = schizophrenia (Clic here for more details about this article) |
4/68. Remission of severe tardive dyskinesia in a schizophrenic patient treated with the atypical antipsychotic substance quetiapine.In a single inpatient case study, a schizophrenic patient with tardive dyskinesia after prolonged treatment with typical neuroleptics was treated with the new atypical neuroleptic quetiapine, a dibenzothiazepin-derivative. Within 2 weeks of treatment with quetiapine, symptoms of tardive dyskinesia improved; 10 weeks after starting treatment tardive dyskinesia stopped completely. Over the same period, dopamine D2 receptor occupancy decreased substantially, as measured by IBZM-SPECT after 14 and 77 days of treatment.- - - - - - - - - - ranking = 20.473682766881keywords = schizophrenic (Clic here for more details about this article) |
5/68. Tardive dystonia provoked by concomitantly administered risperidone.Two cases of tardive dystonia are reported. The first case was an 18-year-old schizophrenic woman suffering from parkinsonism and hypotension induced by antipsychotic drugs. risperidone (4 mg/day) was added to her drug regimen and after increasing the dosage to 6 mg/day, she began to exhibit retrocollis. The second case was a 61-year-old woman who had schizophrenia and tardive dyskinesia. After replacing chlorpromazine (75 mg/day) with risperidone (4 mg/day), she began to exhibit retrocollis. The retrocollis in both cases was considered to be tardive dystonia provoked by risperidone administered concomitantly with other antipsychotics. risperidone is reported to produce few extrapyramidal symptoms, but these cases suggested that changing from other drugs to risperidone, or rapidly increasing risperidone dosage, may provoke tardive syndrome.- - - - - - - - - - ranking = 5.0947365533763keywords = schizophrenic, schizophrenia (Clic here for more details about this article) |
6/68. Improvement of tardive dyskinesia with risperidone: a case report.This case report illustrates the improvement of tardive dyskinesia (TD) and psychotic symptoms in an elderly Thai female with chronic schizophrenia with a long history of conventional antipsychotic exposure following the treatment with risperidone 2 mg/day. TD disappeared in 9 months and continued to be in remission at her 5-month follow-up visit recently.- - - - - - - - - - ranking = 1keywords = schizophrenia (Clic here for more details about this article) |
7/68. Quetiapine treatment of children with Tourette's syndrome: report of two cases.Two children with Tourette's syndrome and comorbid disorders were treated with quetiapine, an atypical antipsychotic successfully used in patients with psychoses and schizophrenia with low incidence of extrapyramidal side effects. Clinical observations and standardized rating scales suggested that this drug produced beneficial effects on tics and other symptoms. Adverse effects (at low doses) were minimal. Because it was suggested that tic efficacy of the newer antipsychotics was related to higher D2 occupancy (with the exception of quetiapine and clozapine, which have relatively low D2 activity), it is hypothesized that tic patients are D2 sensitive and need lower doses of medications. These children were treated naturalistically and were reported retrospectively because of their encouraging outcomes. However, these findings should be interpreted with caution, because no contrast groups, drug withdrawal, or placebo were utilized. Controlled studies are needed to determine the efficacy of quetiapine in the treatment of Tourette's syndrome.- - - - - - - - - - ranking = 1keywords = schizophrenia (Clic here for more details about this article) |
8/68. Tardive dystonia associated with olanzapine therapy.A 21-year-old man with the diagnosis of paranoid schizophrenia was admitted to our clinic with cervical dystonia developing at the end of the first year of olanzapine therapy. The present case suggests that tardive dystonia in this patient is most likely associated with olanzapine administration as this is the main antipsychotic he received. Regarding the few case reports of olanzapine-associated tardive syndromes, patients taking olanzapine should be carefully screened for the appearance of tardive movements.- - - - - - - - - - ranking = 1keywords = schizophrenia (Clic here for more details about this article) |
9/68. Quetiapine-induced improvement of tardive dyskinesia in three patients with schizophrenia.There are very rare cases indicating the effectiveness of the atypical antipsychotics in the treatment of tardive dyskinesia except clozapine. We report three patients with schizophrenia who demonstrated improvement of tardive dyskinesia following treatment with quetiapine; two of them were unable to use clozapine because of intolerable side-effects.- - - - - - - - - - ranking = 5keywords = schizophrenia (Clic here for more details about this article) |
10/68. Improvement of tardive dyskinesia following switch from neuroleptics to olanzapine.The authors report two cases of schizophrenia in which olanzapine proved to be an efficacious antipsychotic medication associated with the remission of movement disorder.- - - - - - - - - - ranking = 1keywords = schizophrenia (Clic here for more details about this article) |
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