1/12. Unilateral distal extremity swelling with pitting oedema in giant cell arteritis.We describe a case of an 82-year-old woman with giant cell arteritis, who developed unilateral pitting oedema of the dorsum of the right hand, foot and distal part of the right forearm as well as tenosynovitis of the right wrist extensors, mild synovitis of the right wrist, metacarpophalangeal and metatarsophalangeal joints, during relapse of giant cell arteritis. Increase of corticosteroids resolved the giant cell arteritis, pitting oedema and tenosynovitis.- - - - - - - - - - ranking = 1keywords = giant (Clic here for more details about this article) |
2/12. Adverse effects associated with a bioabsorbable guided tissue regeneration device in the treatment of human gingival recession defects. A clinicopathologic case report.This clinicopathologic case report documents an adverse effect associated with the use of a polylactic acid-based barrier in the treatment of human gingival recession defects. A total of 27 consecutively treated patients, in whom guided tissue regeneration with a polylactic acid barrier was used to correct gingival recession defects, were evaluated. This adverse effect consisted of a midradicular-apical swelling, generally asymptomatic, with no apparent predilection for gender, age, tooth type or location (maxilla/mandible), or surgical procedure. It was observed in 14 of 27 (52%) patients and 22 of 41 (54%) defects. The swelling decreased in size over time and in most cases, it completely resolved within 12 months postsurgery. Histopathologic evaluation of a 14-week specimen indicated characteristics (multinucleated giant cells, foamy macrophages) consistent with a foreign body reaction. These findings suggest that patients undergoing GTR procedures with synthetic absorbable devices for the treatment of gingival recession defects should be advised of the possible occurrence of such an adverse effect.- - - - - - - - - - ranking = 0.14285714285714keywords = giant (Clic here for more details about this article) |
3/12. Acute transient ophthalmomalacia in giant-cell arteritis. Report of a case.Transient bilateral corneal oedema due to ocular hypotension is reported in giant-cell arteritis. The greatly impaired visual acuity gradually returned to normal on steroid medication. A visual field defect remained in the left eye. The diagnosis of giant-cell arteritis was confirmed by arterial biopsy. The disease involved the pericranial arteries as well as the ophthalmic artery on both sides, probably also the long ciliary arteries, which might explain the ophthalmomalacia. Apparently, only six cases are on record.- - - - - - - - - - ranking = 0.85714285714286keywords = giant (Clic here for more details about this article) |
4/12. Giant frontal sinus mucocoele with intracranial extension and orbital displacement in an elderly Nigerian.Mucocoele of the frontal sinus presents with initial sign of forehead swelling in about 10% of cases, and cases with huge intracranial extension have been reported to be rare. We present a case of a giant frontal sinus mucocoele with intra-cranial and intra-orbital extensions exerting a mass effect on the anterior cranial fossa in a 78 year old Nigerian female with resultant forehead swelling, proptosis and total blindness of the left eye. diagnosis was made on clinical and radiological basis, and enucleation using coronal flap approach was done. Immediate repair of the resultant frontal bone defect was effected through the use of a curved 0.5mm stainless steel wire fixed in 3 layers across the defective frontal bone over which the soft tissues of the forehead were undermined for primary closure on sound bone. This approach was considered more appropriate than a split rib graft in view of the patient's age. No evidence of recurrence was recorded during a one-year post-surgery follow-up, suggesting that mucocoele, regardless of size can be treated with conservative surgical approach provided all cystic lining and mucocoele are removed.- - - - - - - - - - ranking = 0.14285714285714keywords = giant (Clic here for more details about this article) |
5/12. Cochlear and vestibular epithelia from a patient with Meniere's disease: a case study.Scanning electron microscopy observations were carried out on the cochlear and vestibular epithelia of the left temporal bone of a Meniere's patient. There was almost complete absence of hair cells in the basal turn of the cochlea. The outer hair cells of the second turn presented an abnormal shortening of the shorter stereocilia within a tuft, reminiscent of the specific atrophy of the short and middle stereocilia in the ciliary tufts of outer hair cells in the guinea pig with experimental hydrops. The cilia of the inner hair cells showed fusion and giant cilia formation. hair cells were observed in the apical turn which showed no pathological features in particular. In the saccular epithelium there were a number of striking features including, loss of the kinocilium, loss of ciliary tufts, swelling of the sensory cells, holes in the epithelium, and sensory cells pushed out and lying on the surface. The utricular epithelium was less perturbed and showed only relatively small protrusions from the epithelial surface. Similar observations have earlier been made on the vestibular epithelium in experimental hydrops. After taking into consideration the relatively long delay to fixation (12 hours) it appeared that the sacculus was more fragile and prone to autolysis than the other organs suggesting that the in-vivo pathology was manifested in particular in that organ as would be predicted from Meniere's symptoms.- - - - - - - - - - ranking = 0.14285714285714keywords = giant (Clic here for more details about this article) |
6/12. Bilateral giant iliopsoas bursitis presenting as refractory edema of lower limbs.A 69-year-old man with rheumatoid arthritis presented with bilateral leg swelling. Magnetic resonance studies revealed bilateral giant iliopsoas bursitis with intrapelvic expansion and compression of pelvic vessels and bladder. The case was refractory to intensive systemic and local medical treatment.- - - - - - - - - - ranking = 0.71428571428571keywords = giant (Clic here for more details about this article) |
7/12. Anterior ischaemic optic neuropathy: recurrent episodes in the same eye.Anterior ischaemic optic neuropathy is characterised by a sudden, painless loss of vision, optic disc oedema, and nerve fibre bundle visual field defects. It may be associated with giant cell arteritis but is usually idiopathic. Although subsequent involvement of the second eye is common, more than one episode in the same eye is extremely rare. Four patients with recurrent anterior ischaemic optic neuropathy in the same eye are described.- - - - - - - - - - ranking = 0.14285714285714keywords = giant (Clic here for more details about this article) |
8/12. knee-joint rupture with giant antefemoral cyst formation.A case of a patient with Reiter's disease, whose ruptured knee-joint effusion extended proximally along the femur to just below the inguinal ligament, and simulated an iliofemoral thrombosis, is reported. The mechanisms of joint rupture, and the need to differentiate it from thrombophlebitis, are discussed.- - - - - - - - - - ranking = 0.57142857142857keywords = giant (Clic here for more details about this article) |
9/12. Facial swelling and giant cell arteritis.A 62-year-old white woman presented with severe facial swelling, glossitis, and odynophagia. giant cell arteritis (GCA) was diagnosed on the basis of temporal artery biopsy, and the patient responded to corticosteroids. GCA may rarely involve vessels of the mouth and face, resulting in unusual clinical manifestations. Early recognition and treatment are important.- - - - - - - - - - ranking = 0.57142857142857keywords = giant (Clic here for more details about this article) |
10/12. The rash of measles is caused by a viral infection in the cells of the skin: a case report.Measles skin rash was immunohistochemically examined in an effort to detect virus antigen in skin samples taken from a 15-year-old girl with measles. A sectioned specimen obtained by punch biopsy from a 2nd-day skin lesion showed localized parakeratosis and acanthosis with multinucleated giant cells in the epidermis, thickening and cellular edema of epithelia in the hair follicles, and vascular dilation in the papillary plexus. measles virus antigen was detected by ABC immunoperoxidase in the epidermis, follicular epithelia, and lympho-histiocytic cell infiltrates in the upper of the dermis. This rash deemed to be caused in part by direct viral infection of the epidermal cells.- - - - - - - - - - ranking = 0.14285714285714keywords = giant (Clic here for more details about this article) |
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