1/11. Solid facial edema preceding a diagnosis of retro-orbital B-cell lymphoma.Persistent solid facial edema is a rare condition of unknown cause. Although acute facial edema has been associated with numerous disease processes such as infections, neoplasms, immune disorders, inflammation, neuropathic processes, drugs, mechanical obstructions, and trauma, solid facial edema has most often been associated with acne vulgaris. We report the first case, to our knowledge, of solid facial edema preceding a diagnosis of a subcutaneous scalp and orbital/periorbital B-cell lymphoma.- - - - - - - - - - ranking = 1keywords = vulgaris (Clic here for more details about this article) |
2/11. Lipoprotein glomerulopathy associated with psoriasis vulgaris: report of 2 cases with apolipoprotein e3/3.Lipoprotein glomerulopathy (LPG) is a rare disease, characterized by a special histology, including dilated glomerular capillaries filled with pale-stained and meshlike lipoprotein thrombi. It always presents with proteinuria or nephrotic syndrome. Although hyperlipidemia is not always seen, most patients have type III hyperlipoproteinemia with apolipoprotein (apo) E2/3 phenotyping. Although the clinical feature of LPG is rarely described, LPG associated with other glomerulopathy, including IgA nephropathy, membranous nephropathy, and lupus nephritis, has been documented. Until now, there have been no reports of psoriasis vulgaris associated with LPG. The authors present 2 cases of LPG with apo E3/3 genotyping associated with psoriasis vulgaris. The first patient was a 65-year-old woman who presented with nephrotic syndrome with daily urinary protein loss of 9.05 g and itchy erythematous scaly plaques on her trunk and lower limbs for 1 year. The renal biopsy results showed LPG, and the skin biopsy results showed psoriasis. The second patient was a 50-year-old man with history of psoriasis over his trunk and 4 limbs for 30 years. He also presented with nephrotic syndrome with daily urinary protein loss of 7.55 g. The renal biopsy results also showed LPG. The genotype of apo E showed E3/3, and lipoprotein electrophoresis showed a type III hyperlipoproteinemia-like pattern in both cases. The authors suggest that presence of apo E3/3 genotype cannot rule out the diagnosis of type III hyperlipoproteinemia and LPG. Besides, LPG should be included in the differential diagnosis of psoriatic patients with nephrotic syndrome, especially in Asian patients who show poor response to traditional therapy. Renal biopsy should be performed to make the definitive diagnosis.- - - - - - - - - - ranking = 6keywords = vulgaris (Clic here for more details about this article) |
3/11. Solid facial edema of acne: failure of treatment with isotretinoin.Solid facial edema of acne is a rare persistent skin condition which occurs as a late complication of acne vulgaris. It is difficult to treat and isotretinoin seems to be the most effective agent. Here we present a 25-year-old man with a facial edema which arose after the complete remission of acne. Treatment with isotretinoin for 4 months was unsuccessful in this case.- - - - - - - - - - ranking = 1keywords = vulgaris (Clic here for more details about this article) |
4/11. The painful purple digit: an alarming complication of candida albicans antigen treatment of recalcitrant warts.candida albicans (CA) antigen immunotherapy for recalcitrant warts is a novel treatment that has had much success in the recent past. Although several side effects are well documented in the literature, we report a new adverse reaction to CA antigen immunotherapy for verruca vulgaris of the distal fingertip. Our patient received an intradermal injection of CA antigen solution into periungual warts located on the distal left thumb and distal subungual area of the left index finger. Within 24 hours, the patient reported pain, edema, and a purple hue to only the index finger. Incision of the finger demonstrated no hematoma or compartment syndrome. Although the etiology is unknown, we believe the condition was most likely due to edema and vascular compromise secondary to a vigorous delayed-type hypersensitivity reaction, possibly leading to cyanosis of the distal index finger. We report this case to make physicians who use intralesional CA antigen aware of a new possible complication at this anatomic location.- - - - - - - - - - ranking = 1keywords = vulgaris (Clic here for more details about this article) |
5/11. Solid facial edema as a complication of acne vulgaris: treatment with isotretinoin and clofazimine.We present two patients, a 20-year-old female and an 18-year-old male, who suffered from persistent solid facial edema as a complication of acne vulgaris. They were treated with isotretinoin with moderate response and thereafter with lymph massage with further response. The female patient also received clofazimine with good response.- - - - - - - - - - ranking = 5keywords = vulgaris (Clic here for more details about this article) |
6/11. Solid facial edema as a complication of acne vulgaris: treatment with isotretinoin.A case of persistent solid facial edema is described in a 17-year-old boy with moderate papulocystic acne. After a 20-week course of isotretinoin, the acne vulgaris resolved, and there was a moderate reduction in the facial edema.- - - - - - - - - - ranking = 5keywords = vulgaris (Clic here for more details about this article) |
7/11. Solid facial edema as a complication of acne vulgaris.Persistent solid edema of the face in four healthy young adults seemed to be secondary to preexisting acne vulgaris. Elastic compression and intensive acne therapy were of minimal benefit in resolving the edema. Facial inflammation accompanying acne should be recognized as a rare complication of the acne process.- - - - - - - - - - ranking = 5keywords = vulgaris (Clic here for more details about this article) |
8/11. Solid persistent facial edema of acne: successful treatment with isotretinoin and ketotifen.A 20-year-old man suffering from acne vulgaris since the age of 12 developed a solid persistent inflammatory edema of the face through the last 2 years. The edema was resistant to conventional treatment of acne including various systemic and topical antibiotics, isotretinoin and interferon-gamma. Histopathologic examination revealed an extensive fibrosis of the middle and deeper corium with a dense lymphohistiocytic perivascular infiltrate, notably with many mast cells. The therapeutic combination of oral isotretinoin (0.5 mg/kg body weight daily) and ketotifen (2 mg daily) led to complete resolution of all facial lesions. The pathogenesis of persistent edema remains mysterious but may be related to chronic inflammation resulting in obstruction of lymph vessels or fibrosis induced by mast cells.- - - - - - - - - - ranking = 1keywords = vulgaris (Clic here for more details about this article) |
9/11. Surgical treatment of solid facial edema: when everything else fails.A case of persistent solid facial edema is presented to illustrate and discuss this rare, poorly understood condition. It is most frequently a sequela of acne vulgaris, but it can also be caused by other congenital, infectious, and inflammatory processes. This entity is notoriously difficult to treat. Many therapeutic modalities have been tried. Early treatments with isotretinoin, clofazimine, and ketotifen have been occasionally effective while no treatment has been proven successful in the later stages. This is probably the first time that surgical treatment of this problem has been reported. This experience and a review of the literature may prove helpful to other practitioners in our specialty.- - - - - - - - - - ranking = 1keywords = vulgaris (Clic here for more details about this article) |
10/11. Solid facial edema as a complication of acne vulgaris.A case of persistent solid facial edema in an 18-year-old man from india with papulopustular acne vulgaris is reported. Acne lesions responded well to systemic antibiotic and topical antiacne treatment, whereas there was a moderate reduction in the facial edema with a course of systemic steroid therapy.- - - - - - - - - - ranking = 5keywords = vulgaris (Clic here for more details about this article) |
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