1/11. Single lung transplantation for eosinophilic granulomatosis.A 26-year-old woman with end-stage lung disease due to eosinophilic granulomatosis had single right lung transplantation with an excellent function result that persists beyond 9 months of follow-up. Single lung transplantation offers excellent palliation to selected patients with end-stage lung disease.- - - - - - - - - - ranking = 1keywords = granulomatosis (Clic here for more details about this article) |
2/11. Testicular schistosomiasis simulating malignancy. Case report.A case is reported on a 13-year-old boy with schistosomiasis in his right testis, simulating a malignant tumor. The tumor was excised, and since freeze-microscopy showed granulomatosis without malignancy, the testis was saved. schistosomiasis is shortly reviewed. It is emphasized, that testicular involvement is rare.- - - - - - - - - - ranking = 0.2keywords = granulomatosis (Clic here for more details about this article) |
3/11. Allergic necrotizing eosinophilic granulomatosis.Allergic necrotizing eosinophilic granulomatosis (ANEG) is a rare entity characterized by peripheral eosinophilia, hepatosplenomegaly, dyspnea, and lymphadenopathy. An unusual patient with ANEG is described in which the presenting feature was an extensive granulomatous lesion of the face. The patient's condition progressively deteriorated despite multiple therapies, and she finally succumbed to her disease.- - - - - - - - - - ranking = 1keywords = granulomatosis (Clic here for more details about this article) |
4/11. Eosinophilic granulomatous lymphadenopathy: association with hyper-IgE and eosinophilia.Cervical lymph node enlargement is probably the most frequently detected childhood lymphadenopathy. We report 2 cases of cervical lymphadenopathy in children associated with hyper-IgE and eosinophilia, displaying the features of necrotizing eosinophilic granulomatosis. Immunohistochemical analysis and a serological work-up failed to elucidate the underlying etiology. We would like to call the attention of physicians and pathologists to this unusual clinical picture, different from the fatal form of necrotizing eosinophilic granulomatosis, and we suggest a role for the eosinophils in the pathologic appearance of the lymph nodes.- - - - - - - - - - ranking = 0.4keywords = granulomatosis (Clic here for more details about this article) |
5/11. histiocytosis X (Langerhans' cell granulomatosis) of the thymus. A clinicopathologic study of four childhood cases.Four cases of histiocytosis X (Langerhans' cell granulomatosis) involving the thymus are presented. All the patients were children, their age at diagnosis ranging from 2 months to 8 years. In two cases, the disease seemed restricted to the thymus; in the other two, there was extrathymic involvement. The treatment was generally in the form of surgical excision. All the patients are alive and well on follow-up. The light-microscopic appearance was that classically described for histiocytosis X in all cases. Staining for S-100 protein was strongly positive in the two cases in which it was carried out.- - - - - - - - - - ranking = 1keywords = granulomatosis (Clic here for more details about this article) |
6/11. The spectrum of eosinophilic infiltration of the gastrointestinal tract and its relationship to other disorders of angiitis and granulomatosis.Six cases of eosinophilic infiltration of the gastrointestinal tract were studied. Three cases were of the diffuse infiltrative variety (eosinophilic enteritis, two cases; eosinophilic peritonitis, one case), and three cases were of the circumscribed variety (so-called inflammatory fibroid polyp). Two of the infiltrative lesions showed necrotizing granulomas identical to those described by Churg and Strauss; one of the two also showed active vasculitis. One circumscribed lesion occurred in a patient with polyarteritis nodosa. Necrotizing eosinophilic granulomas were also noted in this lesion. Our observations suggest that the two forms of eosinophilic infiltration of the gastrointestinal tract are parts of a disease spectrum. Supporting evidence in the literature is presented. The relationship of this group of eosinophilic lesions to the hypereosinophilic syndrome, allergic granulomatosis and angiitis of Churg and Strauss, and polyarteritis nodosa is discussed.- - - - - - - - - - ranking = 1keywords = granulomatosis (Clic here for more details about this article) |
7/11. Allergic granulomatosis and angiitis (Churg-Strauss).An autopsy case of allergic granulomatosis and angiitis of Churg and Strauss is presented. The patient with a history of bronchial asthma of 3 years duration, a mild fever and hypereosinophilia, died in status asthmaticus. Cortocosteroid therapy was not given. The autopsy revealed severe eosinophilic pneumonia, disseminated necrotizing vasculitis of small arteries and veins in various stages, and extravascular granulomatous nodules. The involved organs were the lungs, liver and gastrointestinal tract, but the heart and kidneys were free from these lesions. The differences from the reported cases were discussed.- - - - - - - - - - ranking = 1keywords = granulomatosis (Clic here for more details about this article) |
8/11. A limited form of churg-strauss syndrome: ocular and cutaneous manifestations.A case that supports the concept of a limited form of Churg-Strauss allergic granulomatosis was studied. The patient had a syndrome that was initially confined to the conjunctiva and subsequently displayed cutaneous and subcutaneous lesions. At no time was there any evidence of systemic involvement. Asthma appeared ten years before the onset of the present disease. The characteristic histologic findings consisted of diffuse tissue eosinophilia, and eosinophilic necrotizing and nonnecrotizing granulomatosis. The last, as well as conjunctival involvement, has not been previously described in churg-strauss syndrome to our knowledge. Thus, this entity most likely represents a variant of the classic churg-strauss syndrome, lacking the multiple organ system involvement that occurs in the latter. The patient responded well to therapy with corticosteroids and as of this writing has been free of disease for about 2 1/2 years.- - - - - - - - - - ranking = 0.4keywords = granulomatosis (Clic here for more details about this article) |
9/11. pregnancy in a patient with eosinophilic granulomatosis of the lung: a case report.BACKGROUND: There are three syndromes of histiocytosis X: eosinophilic granulomatosis of the lungs, hand-Schuller-Christian disease, and Letterer-Siwe disease. Although there have been five case reports of hand-Schuller-Christian disease in pregnancy, we found none describing pregnancy in patients with eosinophilic granulomatosis. CASE: We present a report of eosinophilic granulomatosis of the lungs in pregnancy. The patient's pregnancy was complicated by fetal growth retardation (FGR) and oligohydramnios, but resulted in the delivery of a healthy infant. Her pulmonary disease remained stable. CONCLUSION: pregnancy does not appear to exacerbate pulmonary eosinophilic granulomatosis. In this patient, pregnancy was complicated by FGR and oligohydramnios. This case report may be valuable in counseling patients with eosinophilic granulomatosis who are currently pregnant or contemplating pregnancy.- - - - - - - - - - ranking = 1.8keywords = granulomatosis (Clic here for more details about this article) |
10/11. erdheim-chester disease with prominent pulmonary involvement associated with eosinophilic granuloma of mandibular bone.We report a patient with eosinophilic granuloma localized to the left mandible who was subsequently shown to have erdheim-chester disease involving the lower extremities, omentum and lung. The diagnosis of eosinophilic granuloma was based on the presence of typical CD1a Langerhans' cell granulomas in a biopsy of mandible. The diagnosis of erdheim-chester disease was established on the basis of the pattern of radioisotopic uptake by long bones, seen on a technetium bone scan, and the presence of characteristic histopathological features in biopsies of lung and peritoneum. The pathological findings in lung were compatible with the abnormalities observed by tomodensitometry, but strikingly different from those seen in Langerhans' cell granulomatosis. The differences in the histological features of pulmonary involvement seen in the two diseases, and the possible relationship between Langerhans' cell granulomatosis and erdheim-chester disease, are discussed.- - - - - - - - - - ranking = 0.4keywords = granulomatosis (Clic here for more details about this article) |
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