1/9. Primary epidural hemangiopericytoma in the lumbar spine: a case report.STUDY DESIGN: A case report of primary epidural hemangiopericytoma in the lumbar spine and a review of the literature are presented. OBJECTIVE: To present the result of pathologic diagnosis using immunohistochemical staining and the treatment of spinal hemangiopericytoma. SUMMARY OF BACKGROUND DATA: Spinal hemangiopericytoma is a very rare soft tissue tumor with specific pathologic features and a clinical course featuring high rates of recurrence and metastasis. methods: A 39-year-old woman reported numbness in both legs. Neither sensory abnormalities nor muscle weakness was present in her lower extremities. Magnetic resonance imaging showed a tumor dorsal to the thecal sac at L1-L2. After L1 and L2 laminectomy, the tumor with its dural base was resected en bloc. RESULTS: The patient's clinical and neurologic symptoms disappeared after surgery. Microscopic examination showed oval- or spindle-shaped cells with slightly acidic cytoplasm and oval nuclei. silver staining emphasized fibers around tumor cells. The test results for the tumor cells were positive for vimentin staining, but negative for alpha-TM staining using thrombomodulin, a marker for endothelial cells. On the basis of these pathologic findings, the tumor was diagnosed as a hemangiopericytoma, a type of tumor composed of mesenchymal hemangiopericytes. Neither recurrence nor metastasis of the tumor was found during the 2-year follow-up period after surgery. CONCLUSIONS: Soft tissue hemangiopericytoma is a well-recognized entity considered to be an aggressive neoplasm with a high rate of recurrence and a propensity to metastasize. Immunohistochemical investigation was essential for the diagnosis of this tumor. Although hemangiopericytoma very rarely occurs in the spine, surgeons treating patients with this tumor should be aware of its metastatic potential.- - - - - - - - - - ranking = 1keywords = neoplasm (Clic here for more details about this article) |
2/9. Epidural B cell non-Hodgkin's lymphoma associated with chronic subdural hematoma.BACKGROUND: Chronic subdural hematoma generally occurs in elderly patients, who are also prone to neoplasm. However, the association of chronic subdural hematoma and intracranial neoplasm is rare. CASE DESCRIPTION: An elderly woman harboring a chronic subdural hematoma underlying an epidural extension of a malignant B cell non-Hodgkin's lymphoma is reported. Infiltration of the tumor and obstruction of the dural veins with stasis and rupture of the capillary net may have been the mechanism that led to formation of the hematoma. CONCLUSIONS: In elderly patients harboring chronic subdural hematoma with mural isodensity on CT who have no history or an uncertain history of head trauma, one should consider the possibility of neoplasm, although it is rare. Chronic subdural hematoma associated with epidural extension of B cell non-Hodgkin's lymphoma is exceptional. Screening for other systemic manifestations should be carried out. radiotherapy, alone or in combination with chemotherapy, should be considered after surgical removal.- - - - - - - - - - ranking = 3keywords = neoplasm (Clic here for more details about this article) |
3/9. Thoracic epidural hemangiopericytoma. Case report.hemangiopericytoma is an uncommon mesenchymal neoplasm that rarely affects the spinal canal. We report a case of thoracic epidural hemangiopericytoma in a 39-year-old man with symptoms of spinal cord compression studied by myelo-computed tomography (CT) and magnetic resonance imaging (MRI). Total resection was followed by complete recovery. Postoperative radiotherapy was performed. The clinical, radiological, and histological findings of epidural spinal hemangiopericytoma are reviewed in the light of relevant literature- - - - - - - - - - ranking = 1keywords = neoplasm (Clic here for more details about this article) |
4/9. Purely epidural spinal meningioma mimicking metastatic tumor: case report and review of the literature.STUDY DESIGN: Case report. OBJECTIVES: To report a rare case of purely extradural spinal meningioma in a patient with previous history of malignant disease and to discuss the potential pitfalls in differential diagnosis and treatment of intraspinal extramedullary masses. SUMMARY AND BACKGROUND DATA: Spinal meningiomas located purely in the extradural space are rare, and they may easily be confused with malignant neoplasms that are much more common in this location. methods: An asymptomatic intraspinal extramedullary mass in the thoracolumbar region was detected by magnetic resonance imaging in a 75-year-old woman with previous history of malignant disease. RESULTS: The purely extradural lesion was completely excised via a dorsal approach. The intraoperative and postoperative histologic examination revealed a meningioma. The patient is symptom free 18 months after surgery without radiologic recurrence. CONCLUSION: Extradural spinal meningiomas may mimic metastatic disease. attention needs to be drawn to this dangerous preoperative and intraoperative misinterpretation, which may easily entail an inadequate therapy. Intraoperative histology is mandatory for optimal surgical decision-making.- - - - - - - - - - ranking = 1keywords = neoplasm (Clic here for more details about this article) |
5/9. Primary epidural malignant hemangiopericytoma of thoracic spinal column causing cord compression: case report.CONTEXT: hemangiopericytoma is an uncommon mesenchymal neoplasm that rarely affects the spinal canal. Primary malignant hemangiopericytoma of the spinal column is extremely rare. CASE REPORT: We report on a case of primary epidural malignant hemangiopericytoma of the thoracic spinal column that invaded vertebral bone and caused spinal cord compression in a 21-year-old man. The patient presented with progressive back pain over a four-month period that progressed to paraparesis, bilateral leg paresthesia and urinary incontinence. The surgical intervention involved laminectomy and subtotal resection of the tumor, with posterior vertebral fixation. Postoperative involved-field radiotherapy was administered. A marked neurological improvement was subsequently observed. We describe the clinical, radiological, and histological features of this tumor and review the literature.- - - - - - - - - - ranking = 1keywords = neoplasm (Clic here for more details about this article) |
6/9. Spinal epidural meningiomas in childhood: a case report.A case of a girl affected by an extradural spinal meningioma is described. This lesion is rare in childhood, and the prognosis may be not favorable. In our case a complete removal of the neoplasm with exeresis of the involved dura resulted in a very good clinical and radiological recovery.- - - - - - - - - - ranking = 1keywords = neoplasm (Clic here for more details about this article) |
7/9. Management of the vertebral artery in excision of extradural tumors of the cervical spine.Extradural tumors of the cervical spine may involve the vertebral artery on one or both sides, posing one of the limiting factors toward the radical resection of such neoplasms. A standard anterior approach may be inadequate for the management of such tumors. An anterolateral approach allows the dissection and mobilization of the vessel, which can then be preserved, resected, or reconstructed with a vein graft. An anterior approach can be supplemented with this for tumor resection and stabilization. This management strategy is described in 10 patients with a variety of tumors.- - - - - - - - - - ranking = 1keywords = neoplasm (Clic here for more details about this article) |
8/9. Primary endodermal sinus tumor presenting with spinal cord compression. Case report.endodermal sinus tumor is an uncommon malignant germ-cell neoplasm. These tumors usually present in childhood or young adulthood as testicular or ovarian masses; however, mediastinal and intracranial tumors have been described. The authors report the occurrence of a primary paraspinal endodermal sinus tumor in a 21-month-old boy who presented with thoracic spinal cord compression. A review of the literature failed to reveal a similar case. The clinical presentation, radiographic characteristics, operative findings, and patient outcome are discussed.- - - - - - - - - - ranking = 1keywords = neoplasm (Clic here for more details about this article) |
9/9. Pain due to epidural tumor in cancer patients. Report of two cases and differential diagnosis.The cases of two patients with inguinal pain as the only symptom of a T12 metastatic lesion is reported. The patterns of pain referrals from tumor lesions to the spine, epidural space, and spinal cord are reviewed. Focal back pain and pain reported in a distal distribution can both be associated with epidural or cord disease. The differential diagnosis of back pain in patients with cancer can be difficult but may be crucial in differentiating important neurological complications of systemic neoplasms.- - - - - - - - - - ranking = 1keywords = neoplasm (Clic here for more details about this article) |