1/21. Sororal occurrence of diffuse esophageal spasm.In this report, we have described two sisters with classical symptoms, radiological appearances, and manometric features of diffuse esophageal spasm. To the best of our knowledge, familial occurrence of this disorder has not been documented previously.- - - - - - - - - - ranking = 1keywords = esophageal spasm, spasm (Clic here for more details about this article) |
2/21. Transition from diffuse esophageal spasm to achalasia.A 19-year-old man first presented with clinical, radiological, and manometric features of diffuse spasm. Within a year his motility disorder progressed to "vigorous" and, finally, classic achalasia. After pneumatic dilatation and subsequent long myotomy, the features of classic achalasia disappeared and he again exhibited radiological and manometric evidence of "vigorous" achalasia. The evolution of this patient's disease provides evidence that diffuse spasm and achalasia are different stages of the same disease and lie at opposite ends of a spectrum of related esophageal motility disorders.- - - - - - - - - - ranking = 0.80008377223956keywords = esophageal spasm, spasm (Clic here for more details about this article) |
3/21. Value and limitations of calcium channel blockade in the treatment of pulmonary hypertension associated with CREST--case reports.Reversible vasospasm has been hypothesized to underlie the development of pulmonary hypertension in patients with CREST. Drugs that prevent arterial spasm have been used to treat pulmonary hypertension with variable results. The disparate pulmonary hemodynamic responses to calcium channel blockade reported herein suggest that CREST patients with mild pulmonary hypertension may have a component of reversible vasospasm responsive to vasodilator therapy, whereas patients with moderate to severe pulmonary hypertension may have fixed vessel lesions precluding a satisfactory response to calcium channel blockade.- - - - - - - - - - ranking = 0.00012565835933303keywords = spasm (Clic here for more details about this article) |
4/21. Steakhouse spasm.Sudden esophageal obstruction after eating poorly chewed meat has been called the Steakhouse syndrome. Some cases have demonstrable esophageal narrowing above which food impacts, but in many patients with identical symptoms no underlying obstruction is demonstrated. We report four patients with acute dysphagia who were unable to swallow liquids or solids for as long as 72-96 h. Onset occurred after eating meat in three patients and after taking psyllium in one. All had a structurally normal esophagus demonstrated by x-ray and endoscopy, but motor disorders were defined by manometry in three. We hypothesize that an underlying motor abnormality led to food impaction and call this presumed spastic variant "Steakhouse spasm." We suspect that this is a common but frequently unrecognized manifestation of esophageal dysmotility.- - - - - - - - - - ranking = 0.00020943059888839keywords = spasm (Clic here for more details about this article) |
5/21. Brainstem lesions due to granular ependymitis in symptomatic diffuse esophageal spasm: a case report.An 80 year-old man had symptomatic diffuse esophageal spasms for a few months. They were documented by radiographic, endoscopic and manometric findings. The post-mortem neuropathological examination showed a granular ependymitis of the fourth ventricle involving the dorsal region of the motor dorsal nuclei of the vagus nerve which showed frank neuronal loss. The muscular wall of the esophagus, its myenteric plexus and the fasciculi of the vagus nerve were histologically normal. This is the first published case of such a brainstem lesion associated with symptomatic diffuse esophageal spasms. These pathological data are compared with those already published on achalasia.- - - - - - - - - - ranking = 1.2keywords = esophageal spasm, spasm (Clic here for more details about this article) |
6/21. Swallow syncope.Swallow syncope is an often misdiagnosed rare disorder due to enhanced vagal tone during eating in patients with underlying esophageal and/or cardiac abnormalities. We present three cases of this disorder, one related to digitalis toxicity and the other two with diffuse esophageal spasm. The investigation, differential diagnosis, prognosis and management of swallow syncope are discussed.- - - - - - - - - - ranking = 0.2keywords = esophageal spasm, spasm (Clic here for more details about this article) |
7/21. Transition from peristaltic esophageal contractions to diffuse esophageal spasm.A patient with dysphagia and chest pain was shown by manometry to have high-amplitude peristaltic esophageal contractions (nutcracker esophagus). Worsening symptoms over the next two years led to the performance of repeated manometric studies, which showed diffuse esophageal spasm. This demonstration of a transition from nutcracker esophagus to diffuse esophageal spasm lends further support for consideration of the nutcracker esophagus as a manometric disorder associated with chest pain or dysphagia. Furthermore, it suggests a pathophysiologic relationship between the nutcracker esophagus, a disorder with preserved peristalsis, and diffuse esophageal spasm, the classic dysmotility considered to be of neurogenic origin.- - - - - - - - - - ranking = 1.4keywords = esophageal spasm, spasm (Clic here for more details about this article) |
8/21. A case of esophageal spasms in amyloidosis.Impairment of esophageal peristalsis in amyloidosis is well known. A patient in whom esophageal spasms and orocricopharyngeal dyscoordination accompanied myeloma-associated amyloidosis is presented below. The different possible mechanisms producing these abnormalities are discussed.- - - - - - - - - - ranking = 1keywords = esophageal spasm, spasm (Clic here for more details about this article) |
9/21. chest pain associated with mitral valve prolapse. Evidence for esophageal origin.The cause of chest pain associated with mitral valve prolapse remains unclear. A young woman with chest pain ascribed to mitral valve prolapse is described. Response of chest discomfort to atenolol therapy had been poor. The patient's chest discomfort and concomitant esophageal spasm were provoked by intravenous infusion of edrophonium chloride during esophageal manometry. A Bernstein acid infusion test also induced her chest pain. review of systems revealed intermittent dysphagia and postprandial heartburn. In certain patients with mitral valve prolapse, esophageal motility disorders may be the cause of chest discomfort.- - - - - - - - - - ranking = 0.2keywords = esophageal spasm, spasm (Clic here for more details about this article) |
10/21. Esophageal spasm following propranolol overdose relieved by glucagon.A case of propranolol overdose complicated by esophageal spasm preventing extrication of an orogastric lavage tube and relieved by intravenous glucagon is presented. Esophageal spasm is an infrequent complication of beta-adrenergic over-dose. Possible mechanisms of esophageal spasm and its relief with glucagon are discussed.- - - - - - - - - - ranking = 0.40020943059889keywords = esophageal spasm, spasm (Clic here for more details about this article) |
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