1/13. Traumatic acremonium atrogriseum keratitis following laser-assisted in situ keratomileusis.A 52-year-old man underwent bilateral laser-assisted in situ keratomileusis. Eight months later, he sustained a penetrating corneal injury to the left eye. A dense white infiltrate, unresponsive to antimicrobial therapy, developed in the corneal stroma. Corneal biopsy and eventual penetrating keratoplasty were performed, and both specimens demonstrated fungal elements with branching, septate hyphae. culture identified the organism as acremonium atrogriseum. Histopathologic features of this organism and its differentiation from other, more common fungal organisms are discussed herein.- - - - - - - - - - ranking = 1keywords = keratitis (Clic here for more details about this article) |
2/13. Recurrent fungal keratitis and endophthalmitis.PURPOSE: To report a case of recurrent fungal sclerokeratitis and endophthalmitis with a very successful outcome due to aggressive combined surgical and medical therapy. To discuss the management of this potentially devastating infection. methods: A 65-year-old man presented with 6 months of left eye redness and irritation after injury from organic matter propelled from an airboat. Initially, he had been treated with foreign body removal, antibiotics, and steroids. He was diagnosed with reactive sclerokeratitis at presentation and was treated with steroids. However, when he did not improve, cultures were obtained and acremonium species filamentous fungi was identified. Despite treatment with appropriate topical and systemic antifungals, his fungal sclerokeratitis progressed to endophthalmitis. Two therapeutic penetrating keratoplasties (PKs) with iridectomy and intraocular amphotericin b were necessary to eradicate the fungal infection. RESULTS: visual acuity was restored to 20/25-3 with correction 9 months after initial presentation. There was no recurrence of fungal infection after the second therapeutic PK. CONCLUSION: The possible reasons for recurrence of fungal infection are discussed. The role of timely and aggressive medical and surgical intervention for fungal sclerokeratitis and endophthalmitis in restoring excellent vision is emphasized.- - - - - - - - - - ranking = 2keywords = keratitis (Clic here for more details about this article) |
3/13. Microsphaeropsis olivacea keratitis and consecutive endophthalmitis.PURPOSE: To report a case of fungal keratitis with consecutive endophthalmitis caused by Microsphaeropsis olivacea. methods: Case report. RESULTS: A 51-year-old man developed fungal keratitis and consecutive endophthalmitis after sustaining a penetrating injury to the right eye. Cultures of the aqueous humor yielded M. olivacea. infection resolved after intraocular fungal debridement, intravitreous amphotericin b, and aggressive topical natamycin and oral fluconazole. Persistent, low-grade smoldering corneal and intraocular inflammation required topical corticosteroid therapy. CONCLUSION: M. olivacea is an exceedingly rare ocular pathogen. The intraocular portion of the infection responded quickly to intravitreal antifungal treatment; however, the course was prolonged by smoldering corneal inflammation. Prompt recognition of intraocular spread and aggressive treatment may be beneficial in fungal infections caused by unusual organisms with uncertain virulence.- - - - - - - - - - ranking = 1.5keywords = keratitis (Clic here for more details about this article) |
4/13. Fungal keratitis caused by scedosporium apiospermum: report of two cases and review of treatment.PURPOSE: We report our experience in treating two cases of scedosporium apiospermum keratitis and provide a review of basic scientific and clinical data regarding the treatment of this visually devastating disease. METHOD: We present a case report and literature review. RESULTS: A 35-year-old woman and a 73-year-old man both reported pain, redness, and a foreign body sensation in the eye after trauma. They were initially treated with antibacterials. When cultures were positive for S. apiospermum, the first patient was treated with fluconazole and amphotericin with good results. The second was treated with fluconazole and natamycin, but the infection persisted and the eye was eventually enucleated. review of the literature showed variable responsiveness of S. apiospermum to antifungal treatment. CONCLUSIONS: It is difficult to predict how S. apiospermum keratitis will respond to treatment, but miconazole appears to be useful in conjunction with other antifungals. Voriconazole shows promise as an effective alternative.- - - - - - - - - - ranking = 1.5keywords = keratitis (Clic here for more details about this article) |
5/13. Rapid molecular diagnosis of posttraumatic keratitis and endophthalmitis caused by alternaria infectoria.The first case of alternaria infectoria ocular infection is reported. keratitis and endophthalmitis developed after eye-perforating trauma from a lemon tree branch. Two months after surgery and empirical steroid and antibiotic treatment, diagnosis by molecular methods was performed. PCR amplification was positive for a fungus after 4 h. Antifungal treatment with amphotericin b and fluconazole was initiated immediately. dna sequence analysis showed alternaria infectoria to be the causal agent. After topical and systemic administration of antifungal treatment, ocular inflammation disappeared and visual acuity improved. dna typing was found to be a useful tool to achieve early identification of the causal agent.- - - - - - - - - - ranking = 1keywords = keratitis (Clic here for more details about this article) |
6/13. pseudallescheria boydii keratitis.We treated a case of post-traumatic keratitis caused by the soil saprophyte, pseudallescheria boydii. The injury was caused by a wood splinter which produced a perforating corneal laceration that was primarily repaired. Signs of corneal infection were not evident until the fourth postoperative week. The organism was eradicated by topical miconazole and natamycin. Subsequent penetrating keratoplasty combined with cataract extraction and intraocular lens implantation has achieved a good visual outcome.- - - - - - - - - - ranking = 1.25keywords = keratitis (Clic here for more details about this article) |
7/13. Ocular injuries caused by magpies.This paper presents a series of six patients with ocular injuries resulting from magpie attacks. Five cases involved children. In two cases the penetration was overlooked initially. In one case the keratitis was caused by bacillus cereus. Full ophthalmic examination, including indirect ophthalmoscopy and microbiological studies, must be undertaken initially to identify unrecognised eye injuries and to prevent the possible sight-threatening complications of vitreal fibrosis with subsequent retinal detachment or endophthalmitis.- - - - - - - - - - ranking = 0.25keywords = keratitis (Clic here for more details about this article) |
8/13. Fungal keratitis caused by scopulariopsis brevicaulis treated successfully with natamycin.PURPOSE: To report a severe case of keratitis caused by scopulariopsis brevicaulis and its response to treatment with natamycin. methods: A 28-year-old farmer suffered a corneal perforation with a piece of wire in the right eye. Two months later, he developed severe infectious keratitis in that eye. RESULTS: S. brevicaulis was cultured from the patient's cornea on Sabouraud agar. The keratitis responded to treatment with topical natamycin 5%. A debridement of the corneal ulcer was also performed. CONCLUSIONS: S. brevicaulis is a rare cause of fungal keratitis. The infection can be difficult to eradicate. This is the first case report of keratitis caused by S. brevicaulis treated successfully with natamycin.- - - - - - - - - - ranking = 2.4842792969622keywords = keratitis, corneal ulcer, ulcer (Clic here for more details about this article) |
9/13. corneal ulcer caused by a wooden foreign body in the upper eyelid 6 months after minor injury.PURPOSE: To describe a case of a wooden foreign body in the upper eyelid that remained asymptomatic for 6 months. CASE REPORT: A 9-year-old boy was presented with moderate upper lid swelling. Medical history was positive for trauma with a wooden stick 6 months ago. At first, the condition resolved under local antibiotic treatment. Three weeks later, the inflammation recurred and a corneal ulcer developed. Examination under general anesthesia revealed a wooden foreign body which had remained in the upper eyelid since the first injury. CONCLUSION: Organic foreign bodies in the eyelid can remain asymptomatic for a long period of time and can play a role in periocular inflammation. In case of doubt, children and other less cooperative patients should be examined under general anesthesia.- - - - - - - - - - ranking = 0.0008261166937301keywords = ulcer (Clic here for more details about this article) |
10/13. Sphaeropsis subglobosa keratomycosis--first reported case.Recurrent keratomycosis is reported due to the coelomycete Sphaeropsis subglobosa, which has not been recognised previously as a human pathogen. infection followed corneal injury by a frayed bamboo cane with implantation of its splinters. Initial successful therapy with 2% clotrimazole topically, to which it was sensitive, was followed by recurrent infection after 39 months, initially a keratitis but progressing to an endophthalmitis. Penetrating keratoplasty was necessary to eradicate the infection. Further isolation of the fungus showed that it had not developed resistance to clotrimazole but had survived dormant, deep in the corneal stroma. S. subglobosa should be considered in bamboo-associated and horticultural injuries.- - - - - - - - - - ranking = 0.25keywords = keratitis (Clic here for more details about this article) |
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