1/18. Focal retinal pigment epithelial dysplasia associated with fundus flavimaculatus.BACKGROUND: One or more focal dysplastic lesions of the retinal pigment epithelium (RPE) occurred in 15 eyes of 10 patients with fundus flavimaculatus. methods: review of patient records including an attempt to obtain follow-up information concerning a history of previous ocular trauma. RESULTS: Mild antecedent ocular trauma occurred to the eye with a dysplastic lesion in two patients. Dysplastic lesions were most frequently solitary and located temporal to the macula. Subretinal neovascularization accompanied two of the dysplastic lesions. The lesions were multifocal and present bilaterally in two patients. CONCLUSIONS: In fundus flavimaculatus, progressive lipofuscin storage is responsible for engorgement and hypertrophy of the RPE. Dysplastic lesions of the RPE probably result from reactive hyperplasia and fibrous metaplasia of RPE cells in response to acute disruption of fragile, hypertrophied RPE cells that may be enormously enlarged in the area of yellow flecks. This disruption may occur in response to trauma, focal inflammation, or other localized stimuli. patients with fundus flavimaculatus should be cautioned concerning the possible role of trauma in causing dysplastic changes in the RPE and visual loss.- - - - - - - - - - ranking = 1keywords = inflammation (Clic here for more details about this article) |
2/18. Nodular anterior scleritis associated with ocular trauma.It is accepted that ocular trauma may be the precipitant of non-infectious uveitis. We report the case of a patient who developed unilateral nodular anterior scleritis following ocular trauma. infection and systemic inflammatory diseases were excluded as causes of the inflammation. Our observations suggest the possibility that ocular trauma may act as a trigger for scleritis.- - - - - - - - - - ranking = 1keywords = inflammation (Clic here for more details about this article) |
3/18. In vivo confocal microscopy in the acute phase of corneal inflammation.Two cases of noninfectious keratitis were studied using in vivo corneal confocal microscopy in addition to routine slit-lamp biomicroscopy. A 10-year-old boy suffered from keratitis in his left eye due to a bee sting and a 20-year-old man had keratitis following corneal blunt trauma. In both cases, we found a honeycomb pattern at the anterior and mid-stromal level of the middle cornea. This honeycomb pattern disappeared in 1 week with steroid treatment. This pattern might be caused by syncytial cell bodies of activated keratocytes, by focal corneal stroma edema, or by polymorphonuclear leukocyte infiltration along with the keratocytes or along preformed channels within the corneal stroma known as Bowman channels. Further analysis in a large number of patients may aid in further understanding in vivo human corneal inflammation.- - - - - - - - - - ranking = 5keywords = inflammation (Clic here for more details about this article) |
4/18. Detection of neutrophils in late-onset interface inflammation associated with flap injury after laser in situ keratomileusis.OBJECTIVE: To report a case with late-onset interface inflammation associated with traumatic flap injury at 7 months after laser in situ keratomileusis (LASIK) and to describe the type of infiltrating cells in the tears of the patient. methods: Interventional case report. A 24-year-old male patient who underwent uneventful LASIK on both eyes received blunt trauma from the tip of a shoe in the left eye 7 months after surgery. The corneal flap of his left eye was lacerated across the pupillary area. Inflammatory cells were observed under the lacerated flap segment. Tear fluid was collected from his left eye 3 days after the injury and assessed by tear cytology. For controls, tears of 2 patients who underwent LASIK and developed no interface inflammation were collected the next day after their surgeries and examined. RESULTS: Tear fluid of the patient with interface inflammation contained numerous neutrophils. tears of control patients contained only a few epithelial cells and cell debris but no inflammatory cells. The inflammation was decreased by systemic and topical steroids. However, irregular astigmatism caused by stromal scarring remained, resulting in decreased best-corrected visual acuity. CONCLUSIONS: Interface inflammation can be caused by late-onset flap injury. neutrophils detected in the tears may reflect a major component of cells infiltrating the interface after LASIK.- - - - - - - - - - ranking = 9keywords = inflammation (Clic here for more details about this article) |
5/18. clostridium sordellii endophthalmitis after suture removal from a corneal transplant.PURPOSE: To report a case of endophthalmitis caused by clostridium sordellii. methods: A 33-year-old man sustained a penetrating injury of the right eye that resulted in several ocular surgical procedures including pars plana vitrectomy, scleral buckling, scleral-sutured posterior chamber intraocular lens, and penetrating keratoplasty. More than 4 years after the penetrating injury he presented for examination with pain, photophobia, redness, decreased vision, and floaters in the right eye. Vitreous culture grew clostridium sordellii. RESULTS: Following intravitreal injection of antibiotics, the patient's vision improved from 3/200 to 20/80 (baseline visual acuity) within 2 days. All signs of inflammation resolved without recurrence. CONCLUSIONS: clostridium sordellii endophthalmitis may have a more benign course than the fulminant endophthalmitis typically seen with other Clostridium species.- - - - - - - - - - ranking = 1keywords = inflammation (Clic here for more details about this article) |
6/18. Non-Hodgkin lymphoma presenting with uveitis occurring after blunt trauma.We report here an unusual patient suffering from visual loss with refractory uveitis which was occured after a blunt trauma to her left eye. While in the hospital cervical lymph node and anterior chamber aspiration cytology with immunohistochemical staining were performed. The histopathologic diagnosis was highly malignant B-cell non-Hodgkin lymphoma. After the inflammation of the eye was regressed with chemotherapy, pars plana vitrectomy-lensectomy was performed. She was free of inflammation and the best corrected visual acuity was increased. However, she had a refractory inflammatory episode with clumps of cells in the anterior chamber 10 months after the operation. Local radiotherapy to the left eye was applied. radiotherapy provided local control and preservation of the vision. The present case is presented in order to emphasize the importance of systemic evaluation in uveitis and possible role of trauma leading migration of atypical cells into the eye.- - - - - - - - - - ranking = 2keywords = inflammation (Clic here for more details about this article) |
7/18. choroidal neovascularization in a child with traumatic choroidal rupture: clinical and ultrastructural findings.choroidal neovascularization in children is uncommon and mostly associated with inflammation, infectious diseases or trauma. The clinical and histological findings of a choroidal neovascular membrane that developed in a 9-year-old boy after traumatic choroidal rupture are reported.- - - - - - - - - - ranking = 1keywords = inflammation (Clic here for more details about this article) |
8/18. Primary and secondary iris cysts.Primary cysts of the iris usually arise from the pigment epithelial layers and are almost always benign, stationary lesions which require no treatment. Those cysts which are secondary to such agents as trauma or inflammation are, however, characterized by progressive enlargement and visual complications. The major clinical significance of iris cysts lies in their similarity to iris melanomas. cysts should be monitored for enlargement and/or other complications such as inflammation or secondary glaucoma.- - - - - - - - - - ranking = 2keywords = inflammation (Clic here for more details about this article) |
9/18. uveitis precipitated by nonpenetrating ocular trauma.Although penetrating trauma is a well-recognized cause of uveitis, the role of nonpenetrating trauma in initiating uveitis is not defined. We analyzed the records of 496 patients seen at the uveitis clinic at our institution. Twenty-four of these 496 patients (4.8%) suspected that the cause of their intraocular inflammation was related to previous nonpenetrating trauma. In contrast, only one of 251 patients (0.4%) attending the general ophthalmology clinic for routine care provided a history of recent trauma or attributed the present ocular complaint to trauma (P less than .02). patients with posttraumatic uveitis were usually male (19 of 24, 79%), younger (31 /- 16 years) than the average patient examined in the uveitis clinic, and more likely to have unilateral disease. In ten (42%) of the patients the trauma was work-related. Bilateral inflammation was seen in eight (one third) of the patients and 17 of 28 patients (71%) had a considerable degree of inflammation posterior to the lens. Many patients had an identifiable cause of uveitis such as ankylosing spondylitis, Reiter's syndrome, sarcoidosis, or acute retinal necrosis; but most patients had no known predisposition. The role of nonpenetrating trauma in initiating uveitis has implications for diagnosis and treatment.- - - - - - - - - - ranking = 3keywords = inflammation (Clic here for more details about this article) |
10/18. Late vitrectomy in double perforating ocular injuries.Three double perforating eye injuries were managed satisfactorily with vitrectomy six to twelve weeks after injury. This timing of surgery may be advantageous, in that inflammation may be less and the risk of hemorrhage lower. All eyes in our series had spontaneous posterior vitreous detachment, making surgery technically easier. Serial ultrasonography is essential in these cases, and in the presence of retinal detachment, earlier surgery may be indicated.- - - - - - - - - - ranking = 1keywords = inflammation (Clic here for more details about this article) |
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