1/25. Intestinal tuberculosis presenting as fever of unknown origin in a heart transplant patient.patients undergoing transplantation have an increased risk of developing infections such as tuberculosis, pneumocystis carinii pneumonia, candida infections or cytomegalovirus infections because of their immunosuppressive therapy with cyclosporin A, azathioprine and steroids. Mycobacterial infection is well recognized as a complication in the immunocompromised host but diagnosis and therapy are very difficult.- - - - - - - - - - ranking = 1keywords = tuberculosis (Clic here for more details about this article) |
2/25. Tuberculous gumma (cutaneous metastatic tuberculous abscess) with underlying lymphoma.Cutaneous tuberculosis is an infrequent first sign of disseminated tuberculosis. We describe a patient with 2 cutaneous ulcerations that grew mycobacterium tuberculosis. Despite an initial response to antimycobacterial therapy, the fever relapsed. After several months, biopsy of a single cervical lymph node showed a T cell-rich B cell lymphoma. Our patient had metastatic tuberculous abscesses (tuberculous gummas), which are secondary to disseminated tuberculosis, and an underlying occult lymphoma, both believed to be sequentially presenting as a fever of unknown origin.- - - - - - - - - - ranking = 0.8keywords = tuberculosis (Clic here for more details about this article) |
3/25. Tuberculosis as a cause of recurrent fever of unknown origin.Recurrent fever constitutes a diagnostic challenge for clinicians, due mainly to the intermittent nature of the fever that results in incomplete investigations. We describe three patients with recurrent fever thought to be due to tuberculosis, and review the 14 previously reported cases who fulfil the criteria of recurrent fever for at least 1 month's duration. The median duration of symptoms before diagnosis was 5 months, and the duration of the febrile bouts ranged from a few hours to 1 week. The most common complaints were constitutional symptoms and abdominal pain, and most patients had significant underlying conditions. The mortality rate was 31%, and was limited to the earlier cases. Routine laboratory studies are not very helpful for the diagnosis of this condition, and chest radiographs showed some alteration in half the cases at the time of diagnosis, although in some cases represented old, healed lesions. PPD testing was positive in most cases, particularly in those without underlying conditions. Empirical antituberculous therapy should be considered in cases of recurrent fever, especially in areas of high prevalence or in patients with predisposing conditions.- - - - - - - - - - ranking = 0.2keywords = tuberculosis (Clic here for more details about this article) |
4/25. Isolated splenic tuberculosis presenting with pyrexia of unknown origin.We report a case of a 62-y-old man who presented with fever, malaise and weight loss. He was diagnosed with pyrexia of unknown origin due to tuberculosis of the spleen. Combination anti-tuberculous therapy was administered and fever gradually subsided after 6 weeks. A 12-month course of anti-tuberculous treatment would appear to be appropriate for the treatment of most patients with splenic tuberculosis.- - - - - - - - - - ranking = 1.2keywords = tuberculosis (Clic here for more details about this article) |
5/25. fever of unknown origin in the setting of hiv infection: guidelines for a rational approach.fever of unknown origin constitutes a common problem in hiv-infected patients that, paradoxically, has received little attention in the literature. A review on this topic collecting data from different series showed that mycobacterial infections, particularly tuberculosis, were responsible for the fever in more than half of the patients. However, the relative frequencies of the different etiologies may vary substantially depending on the local prevalences of certain infections. With the notable exception of tuberculosis, which may develop at any stage of hiv infection, fever of unknown origin usually presents in patients with advanced disease when the CD4 cell count is below 100/microliter. In this overview we stress, from a practical point of view, some points to be considered in the evaluation of the hiv-infected patient who presents with fever of unknown origin, as well as the usefulness and yield of several diagnostic procedures.- - - - - - - - - - ranking = 0.4keywords = tuberculosis (Clic here for more details about this article) |
6/25. Isolated splenic tuberculosis.The authors report two cases of isolated splenic tuberculosis treated since 1989 in Nizam's Institute of Medical Sciences. One case presented as pyrexia of unknown origin (PUO) and another with idiopathic thrombocytopenic purpura (ITP). Both were found to have splenic tuberculosis after splenectomy. Pre operative diagnosis could not be made in these cases. splenectomy followed by antituberculous chemotherapy cured the condition in both the cases. The authors underline the diagnostic difficulties, essentially related to the rarity of this condition inspite of the progress in modern imaging.- - - - - - - - - - ranking = 1.2keywords = tuberculosis (Clic here for more details about this article) |
7/25. Hemophagocytic syndrome as an initial presentation of miliary tuberculosis without pulmonary findings.A 9-y-old girl was admitted with fever, weakness and weight loss. She had pancytopenia in peripheral blood, hypocellularity and hemophagocytosis in bone marrow. Disseminated tuberculosis was diagnosed after a long delay, with involvement of the lungs, bone marrow, liver, spleen and central nervous system. Tuberculosis can be a cause of hemophagocytosis and should be taken into account in the differential diagnosis of fever of unknown origin associated with pancytopenia and hemophagocytosis.- - - - - - - - - - ranking = 1keywords = tuberculosis (Clic here for more details about this article) |
8/25. CT appearances in macronodular hepatosplenic tuberculosis: a review with five additional new cases.Pseudotumoral or macronodular hepatosplenic tuberculosis (HSTB) is rare. Only 31 cases have been documented in imaging literature so far. Presented is the clinico-imaging review with five additional new cases of this uncommon variety. Due to nonspecific wide spectrum of imaging appearances, biopsy is mandatory in almost all cases. Clinical recovery and resolution of lesions on imaging may not be directly proportional.- - - - - - - - - - ranking = 1keywords = tuberculosis (Clic here for more details about this article) |
9/25. Peritoneal tuberculosis in two young immigrants with fever of unknown origin.Two patients with long-standing fever and weight loss underwent extensive diagnostic procedures before peritoneal tuberculosis was diagnosed by explorative laparatomy. By that time they had developed signs of intestinal obstruction. Both recovered after treatment, but one developed serious neurological complications, which could not be explained. Peritoneal tuberculosis is a manifestation of tuberculosis that is often difficult to diagnose. It should be borne in mind when diagnosing patients with fever of unknown origin, especially if they are originally from countries with a high prevalence of tuberculosis.- - - - - - - - - - ranking = 1.6keywords = tuberculosis (Clic here for more details about this article) |
10/25. Cervico-mediastinal tuberculous lymphadenitis presenting as prolonged fever of unknown origin.Prolonged fever of unknown origin (FUO) is a challenging and important medical problem. Tuberculosis is the most frequent cause of FUO, especially in endemic regions, such as developing countries. We present a case of cervico-mediastinal tuberculous lymphadenitis that had been searched and followed up as a prolonged FUO. Especially in endemic areas, tuberculosis should be borne in mind in the differential diagnosis of FUO cases with granulomatous lymphadenitis presenting as prolonged or recurrent fever, even if the cultures and polymerase chain reaction for mycobacterium tuberculosis are negative.- - - - - - - - - - ranking = 0.4keywords = tuberculosis (Clic here for more details about this article) |
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