Cases reported "Fibroma, Ossifying"

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1/5. Peripheral giant cell granuloma: a potentially aggressive lesion in children.

    A slowly enlarging gingival mass with a reddish-purple surface is observed in a school-age boy. The lesion was first noted 3 months ago during a routine oral examination but recently it has increased in size and interferes with eating. A periapical radiograph demonstrated focal loss of the alveolar crestal bone in the mandibular incisor region. The diagnosis of peripheral giant cell granuloma, a benign reactive gingival lesion, is confirmed by histopathologic examination. Early detection and excision of this hyperplastic nodule is important to minimize potential dentoalveolar complications.
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2/5. Long-term follow-up of peripheral ossifying fibroma: report of three cases.

    Peripheral ossifying fibroma is a non-neoplastic enlargement of the gingiva that is classified as a reactive hyperplastic inflammatory lesion. It is possible to misdiagnose peripheral ossifying fibroma as pyogenic granuloma, peripheral giant cell granuloma, or odontogenic tumors. Therefore, histopathological examination is essential for an accurate diagnosis of such lesions. Differential diagnosis is important, because peripheral ossifying fibroma has a tendency to recur. This article describes three cases of peripheral ossifying fibroma, which were followed for 4 years without any sign of recurrence. By presenting these cases, we emphasize the importance of proper excision and aggressive curettage of the adjacent tissues for prevention of recurrence.
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3/5. Cemento-ossifying fibroma of mandibular gingiva: single case report.

    We report a case of a woman presenting a giant cementoossifying fibroma depending of the mandibular gingivae. The evolution of the process was 20 years. Cemento-ossifying fibroma is a relatively rare tumour classified between fibroosseous lesions. This lesion appears within the bone although in some occasions it involves the gingivae soft tissues, as the case we present. It is a slow-growing and well-defined tumorous lesion, because of this, it is considered as a benign lesion. The histologic findings alone may be similar to other pathologies such as osteoblastoma, low-grade osteosarcoma and particularly to fibrous dysplasia. An accurate diagnosis requires careful clinical, radiological and histological correlation in order to make an optimal treatment and an excellent outcome.
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4/5. Familial ossifying fibromas: report of two cases.

    Ossifying fibroma is a benign fibro-osseous lesion of the jaw containing varying amounts of calcified deposits such as bone, cementum or both. This type of lesion is referred to as dysplastic or neoplastic in nature. In 2000, a 52-year-old male patient was referred to our clinic complaining of a giant swelling in the mandibular premolar-molar region. A histopathological diagnosis of ossifying fibroma was made. Three months later, his daughter was admitted with a swelling on her mandible. Following biopsy, this patient was also diagnosed as having ossifying fibroma. The present report describes these two cases of familial and multiple ossifying fibromas.
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5/5. A unique temporal bone lesion resembling juvenile active ossifying myxoma.

    Juvenile active ossifying fibroma (JAOF) is a lesion characterized by early age of onset, slow growth, frequent recurrence, and locally aggressive behavior. Histologically, it consists of three major components: cellular fibrous stroma, osteoid bodies, and myxomatous matrix, which may become cystic. This article describes a case of a slowly growing destructive lesion of the mastoid in a 2-year-old girl with histologic features resembling those of juvenile active ossifying myxoma (JAOM). Histologically, its prominent features were myxoid and fibromyxoid stroma with cystic areas, vascular spaces, bone, and multinucleated giant cells. This is the first pediatric temporal bone lesion with these features recorded These histologic components led to the diagnosis of JAOM of the temporal bone, probably developing in relation to the development of the mastoid air spaces.
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