1/9. Eosinophilic pustular folliculitis: report of seven cases in thailand.Seven cases of eosinophilic pustular folliculitis (EPF) were diagnosed at the Institute of dermatology within the seven years from 1989-1996. There were 4 males and 3 females, age 24-44 years, with durations of the disease before diagnosis ranging from 3 months to 5 years. The face was the most commonly involved area. Lesions also occurred simultaneously on other sites including the chest, trunk, scalp, and palmoplantar areas. diagnosis was made from clinical features, hematologic examinations, and histopathologic pictures. Topical piroxicam gel, 0.5%, and oral indomethacin gave good results; some lesions subsided within a few days, and the remissions lasted for four months to five years.- - - - - - - - - - ranking = 1keywords = palm (Clic here for more details about this article) |
2/9. Eosinophilic pustular folliculitis starting initially only with palmoplantar pustular lesions. Report of a case and review of the literature.We report a 23-year-old Japanese male with eosinophilic pustular folliculitis (EPF) that had started with palmoplantar rash. Only when follicular pustules appeared on the bilateral cheek 31 months later, we revised our initial diagnosis of pustulosis palmaris et plantaris (PPP) to EPF, and all the skin eruptions cleared mostly with indomethacin. A review of the Japanese literature for the past 20 years disclosed that in 207 cases of EPF so far reported, palmoplantar pustular lesion was noted in 38 (18%). Among them, in 16 cases (8%) the skin lesions started first from the palmoplantar region with the average period of 26 months until the appearance of other eruptions of EPF. None of them was diagnosed as EPF when skin lesions were localized only to the palmoplantar region. When we find pustules on the palmoplantar region, we should suspect the possibility of early lesions of EPF as well as PPP. Histopathologic demonstration of multilocular pustules located in the upper epidermis containing numerous eosinophils in the palmoplantar pustular lesions, together with the dramatic therapeutic response to indomethacin greatly favor the diagnosis of EPF.- - - - - - - - - - ranking = 11keywords = palm (Clic here for more details about this article) |
3/9. A novel connexin 26 gene mutation associated with features of the keratitis-ichthyosis-deafness syndrome and the follicular occlusion triad.We report the case of a congenitally deaf white male with mild palmoplantar keratoderma, ichthyosiform scaling, follicular hyperkeratosis, and mild keratitis, features consistent with keratitis-ichthyosis-deafness syndrome. His major problem was severe, disfiguring, inflammatory dissecting folliculitis of the scalp, hidradenitis suppurativa, and cystic acne, features comprising the follicular occlusion triad. This unusual phenotype is associated with a novel heterozygous point mutation (C119T) in the gap junction beta2 gene that substitutes a valine for alanine at codon 40 (A40V) in the connexin 26 protein. Through xenopus oocyte expression studies, this mutant protein was shown to significantly disrupt the function of the specialized gap junctions connecting the cytoplasm of adjacent cells critical for tissue homeostasis. Mutations within the connexin 26 protein are associated with syndromes involving both sensorineural deafness and hyperkeratotic skin disorders. This is the first report of an association between a connexin 26 protein mutation, follicular hyperkeratosis of keratitis-ichthyosis-deafness syndrome, and severe follicular occlusion triad.- - - - - - - - - - ranking = 1keywords = palm (Clic here for more details about this article) |
4/9. Eosinophilic pustular folliculitis (Ofuji disease) manifested as pustules on the palms and soles.Eosinophilic pustular folliculitis (EPF) is clinically characterized by eosinophilic follicular papulopustules that form annular configurations on the face, trunk, and extremities. We describe a case of a patient whose EPF manifested on the soles of the feet, an area that normally does not contain hair follicles. The patient experienced a dramatic therapeutic response to indomethacin.- - - - - - - - - - ranking = 4keywords = palm (Clic here for more details about this article) |
5/9. Eosinophilic pustular folliculitis.Eosinophilic pustular folliculitis is characterized by the spontaneous development of recurrent, sterile papules, pustules, and plaques on the face, trunk, arms, and occasionally the palms and soles. Although the large majority of the reported cases have occurred in Eastern Asians, most patients in the united states have been infants or men seropositive for human immunodeficiency virus. We describe a North American woman with eosinophilic pustular folliculitis who was neither seropositive for human immunodeficiency virus nor of Asiatic descent.- - - - - - - - - - ranking = 1keywords = palm (Clic here for more details about this article) |
6/9. Eosinophilic pustular folliculitis: fungal folliculitis?Eosinophilic pustular folliculitis is a rare condition with no known cause. However, a fungal cause is suggested by (1) tinea-like annular lesions, (2) initial clinical consideration of fungal folliculitis in many reported cases, (3) an association with the acquired immunodeficiency syndrome, and (4) an association with scaly and vesiculopustular lesions of palms and soles. We report a case histologically identical to eosinophilic pustular folliculitis but in which hyphal fungal organisms were demonstrated in one of the involved hair follicles.- - - - - - - - - - ranking = 1keywords = palm (Clic here for more details about this article) |
7/9. Eosinophilic pustular folliculitis.We present the case of an American adult patient with eosinophilic pustular folliculitis. The majority of previously reported patients have been Japanese. Eosinophilic pustular folliculitis is a rare condition characterized by recurrent, peripherally expanding, sterile papulopustules and plaques. hair-bearing areas such as the face, chest, back, and extensor surfaces of the upper arms are usually involved, although palms and soles can be affected as well. Histologic examination shows subcorneal and intrafollicular abscesses and spongiosis of the outer root sheath. The eosinophil is a prominent infiltrating cell, although mononuclear cells and neutrophils may also be seen. There is often a dense perivascular infiltrate of eosinophils in the dermis. Our patient was unusual in that he did not respond to multiple therapeutic regimens.- - - - - - - - - - ranking = 1keywords = palm (Clic here for more details about this article) |
8/9. Eosinophilic pustular folliculitis. Report of two cases with a review of the Japanese literature.Two Japanese patients, a 29-year-old woman and a 21-year-old man, had typical eosinophilic pustular folliculitis characterized by pruritic, tiny, red, follicular papulopustules on the face and trunk and eosinophilia in the peripheral blood. The second patient also had palmoplantar pustular lesions. A review of the literature revealed that this folliculitis primarily affects the seborrheic areas and that in one fifth of the patients palmoplantar lesions are a concomitant finding.- - - - - - - - - - ranking = 2keywords = palm (Clic here for more details about this article) |
9/9. Progressive generalized perforating folliculitis.A case is presented of a 52-year-old female exhibiting a severe progressive generalized perforating folliculitis accompanied by widespread erythroderma, follicular hyperkeratosis, keratoderma of palms and soles, alopecia of scalp and eyebrows, and nail changes. The disease seemed completely resistant to steroids, adrenocorticotropin, PUVA, cytostatic drugs, and aromatic retinoids. This type of skin reaction does not seem to have been described in the dermatologic literature.- - - - - - - - - - ranking = 1keywords = palm (Clic here for more details about this article) |