1/22. Plexiform fibrohistiocytic tumor of the foot.The first case of plexiform fibrohistiocytic tumor in the foot is presented in this article. The tumor developed on the dorsum of the left foot in a 14-year-old female. This tumor was originally described in 1988 by Enzinger and Zhang. Their study indicated that this tumor has a female predominance, median age of 14.5 years, 63% located in the upper extremities, 37.5% recurrence rate, and 3% metastasis rate. These tumors are very unique with a nodular pattern and a cellular component of histiocytes, fibroblasts, and multinucleated giant cells. Typically they are located within the deep dermis and subcutaneous tissue. Immunohistochemical preparations show that the tumor does not stain for S-100 protein, desmin, cytokeratin, factor viii-related protein, or lysozyme. However, it does stain for alpha-1-antitrypsin, alpha-1-antichymotrypsin, alpha-smooth muscle-specific actin, vimentin, and CD68 antibody.- - - - - - - - - - ranking = 1keywords = giant (Clic here for more details about this article) |
2/22. Pedal giant cell tumor of tendon sheath.The authors present a brief review of giant cell tumor of tendon sheath and three case reports. A discussion emphasizing the histologic characteristics of this lesion demonstrates the benign-to-malignant variability of these neoplastic growths. Special attention is directed to a case with aggressive histologic characteristics. Reexcision after surgery should be considered in cases where microscopic examination reveals a lesion with characteristics suggestive of potentially aggressive behavior.- - - - - - - - - - ranking = 5keywords = giant (Clic here for more details about this article) |
3/22. Giant cell tumor of the foot.The author discusses giant cell tumor, often a monostotic bone tumor, as it affects the lower extremity. The lesion is most common at the ends of long tubular bones, and may transform into malignant pathology. Surgical resection with or without bone grafting is an accepted technique for treatment. Recurrent abnormality is possible, and close follow-up of these patients is recommended.- - - - - - - - - - ranking = 1keywords = giant (Clic here for more details about this article) |
4/22. Unusual presentation of a giant cell tumor of the tendon sheath in the foot.Giant cell tumor of the tendon sheath has frequently been described in the hand, but it is much less common in the foot. The case report presents an apparent cystic bony lesion of the proximal phalanx of the second toe of the foot. The operative findings and histological examination revealed a giant cell tumor of the tendon sheath that had eroded the phalanx. The case demonstrates that in the differential diagnosis of a cystic lesion of bone, extrinsic soft-tissue lesions should be considered.- - - - - - - - - - ranking = 5keywords = giant (Clic here for more details about this article) |
5/22. Peripheral gangrene associated with Kawasaki disease.Three American infants with Kawasaki disease (KD) complicated by peripheral extremity gangrene are reported. Eight such patients (only 1 from japan) have been reported previously. These 11 patients, infants less than 7 months old at onset of KD, are predominantly non-Asian. At least nine had associated giant coronary aneurysms, and eight had associated peripheral arterial aneurysms. In eight infants the diagnosis of KD was not established and therapy was not instituted until greater than or equal to 14 days after onset. Peripheral ischemia initially was noted 15-31 days after onset. Although the pathogenesis of this complication is not well understood, it likely includes some combination of local peripheral arteritis, arteriospasm, thrombosis peripherally and/or more proximally (e.g., in an axillary artery aneurysm), and cardiogenic shock. Treatment may include use of antiinflammatory agents such as salicylates and intravenous gamma globulin, vasodilative agents and/or methods, and thrombolytic and/or anticoagulant agents in an attempt to prevent the potentially devastating consequences of progressive gangrene.- - - - - - - - - - ranking = 1keywords = giant (Clic here for more details about this article) |
6/22. Giant cell tumor of the intermediate cuneiform. A case report.Although it has yet to be determined which surgical procedure provides the least chance for recurrence, surgical treatment remains the preferred therapy for giant cell tumors of bone. Few cases of giant cell tumor of the tarsus have been reported in the literature, with less than 10 of these cases occurring in the cuneiforms. When the extent of the tumor is questionable, definitive radiologic techniques should be used to aid in the selection of the most appropriate surgical procedure. Follow-up radiographic examination is critical to ensure that the patient remains tumor free. Yearly chest x-rays are recommended to rule out pulmonary metastasis. Although giant cell tumors represent only 5% to 8% of all benign primary osseous neoplasms of the foot, they have the potential to undergo malignant transformation, increasing the morbidity and mortality to the patient. giant cell tumors of bone are locally aggressive, often occurring adjacent to articular surfaces, and usually are large when diagnosed. It is essential for the surgeon to plan a treatment that not only minimizes the chance of recurrence, but also attempts to preserve function of the involved part.- - - - - - - - - - ranking = 3keywords = giant (Clic here for more details about this article) |
7/22. Case report 734. fibroma of tendon sheath eroding 3rd metatarsal bone.A case is presented of a 37-year-old man with an extrinsic lesion originating in the soft tissue adjacent to the 3rd metatarsal and smoothly eroding the adjacent bone. The operatively confirmed diagnosis of fibroma of tendon sheath was surprising, giant cell tumour of tendon sheath eroding bone being considerably more common; these two lesions are normally impossible to distinguish radiologically.- - - - - - - - - - ranking = 1keywords = giant (Clic here for more details about this article) |
8/22. Ruptured plantar epidermal inclusion cyst with foreign body giant cell reaction.The case of a ruptured, multilobular, plantar epidermal inclusion cyst is presented. The case is notable because the lesion involved the fourth common digital nerve. Magnetic resonance images of the foot are demonstrated. Treatment consisted of surgical excision without recurrence.- - - - - - - - - - ranking = 4keywords = giant (Clic here for more details about this article) |
9/22. MR evaluation of giant cell tumors of the tendon sheath.Giant cell tumor of the tendon sheath (GCTTS) is a benign condition that involves the synovium of the tendon sheaths. Histologically, GCTTS is similar to pigmented villonodular synovitis. The MRI findings in two cases of GCTTS are reported. In both cases, predominantly low signal is seen on T1-weighted, proton density weighted, and T2-weighted images. This information may be useful in distinguishing GCTTS from other mass lesions involving the tendon sheaths.- - - - - - - - - - ranking = 4keywords = giant (Clic here for more details about this article) |
10/22. lower extremity peripheral neuropathy and ischemic ulcers associated with giant cell arteritis.A patient with previously treated, temporal artery biopsy proven, giant cell arteritis (GCA) developed lower extremity ulcers and sensory neuropathy. sural nerve biopsy showed epineural vessels with focal mild chronic inflammation. The lower extremity skin and nerve abnormalities improved after retreatment with prednisone. The rare manifestations of lower extremity skin and peripheral nervous system involvement associated with GCA are discussed. GCA must be considered in lower extremity ischemic processes of the skin and peripheral nervous system.- - - - - - - - - - ranking = 5keywords = giant (Clic here for more details about this article) |
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