1/6. Introduction to some common cutaneous foot conditions and their management.Problems that happen to the body through injury or disease can also happen to the owner's feet, and there are additional complications associated with the feet. Feet are a long way from the core, are in contact with an unclean environment (the ground), can be abused through poor-fitting footwear and are subjected to more general wear and tear than many other parts of the body. There are a large number of conditions affecting the feet, many associated with medical disorders such as diabetes, rheumatoid arthritis or peripheral vascular disease. The symptom of pain often triggers help being sought, but change in the appearance of the skin is a very important indicator of the state of superficial and deeper tissues. health-care professionals may be called upon to comment on these conditions and treat and/or refer accordingly, so a multidisciplinary approach is required. Clinical skill is required to identify the conditions which are treatable, or those which should be referred for treatment by someone in another specialism. This paper provides information for clinicians and interested others in the form of an introduction to some common cutaneous foot conditions through outline case examples and their treatment.- - - - - - - - - - ranking = 1keywords = vascular disease (Clic here for more details about this article) |
2/6. A large ulcer and cutaneous small-vessel vasculitis associated with syphilis infection.Cutaneous vasculitis (CV) is a condition with cutaneous manifestations and possible systemic involvement. The causative factors or associated diseases are usually drugs, infection, collagen vascular disease, or malignancy. syphilis as a cause of cutaneous vasculitis is rare. We report the case of a large cutaneous ulcer and small-vessel vasculitis associated with syphilis infection. We suggest that in apparently idiopathic CV or a chronic ulcer refractory to treatment, screening should be performed to detect any underlying infection such as syphilis. It is important to have a rapid and accurate diagnosis because the lesions are very contagious, but may be rapidly and completely cured by early administration of antibiotic treatment.- - - - - - - - - - ranking = 1keywords = vascular disease (Clic here for more details about this article) |
3/6. Stem cell use in a patient with an ischemic foot ulcer: a case study.stem cell research has been discussed in both the political and popular arenas lately. Some types of stem cell research are controversial; however, not all stem cell research involves harvesting cells from an embryo or an aborted fetus. Another type of stem cell, the adult stem cell, resides within tissues and organs of the body and is responsible for repair after injury. Recent interest has focused on using adult stem cells isolated from a patient's bone marrow to stimulate the development of new blood vessels (a process called angiogenesis) in patients with peripheral vascular disease. These specialized stem cells are referred to as endothelial progenitor cells (EPCs). In laboratory and clinical studies it has been shown that these EPCs are involved in arterial repair and remodeling, as well as angiogenesis. The following case presentation will show how a patient with an ischemic toe ulcer and rest pain, who had no options for conventional revascularization, benefited from the injection of stem cells into her calf muscle. The process of angiogenesis using EPCs will be examined discussing the screening criteria and possible adverse events. The patient's history and progress throughout the recovery period will be reviewed.- - - - - - - - - - ranking = 1keywords = vascular disease (Clic here for more details about this article) |
4/6. Prosthetic vascular graft and autogenous vein graft with free-tissue transfer in attempted lower-limb salvage.Chronic wounds of the lower extremity are frequent causes of osteomyelitis and amputation in patients with peripheral vascular disease. Advances in vascular surgical techniques, allowing distal arterial bypass via synthetic grafts or autogenous vein grafts, have significantly increased the frequency of limb salvage. In the last two decades, this increasing success has contributed to an even greater rate of extremity salvage. The authors report a case of attempted limb preservation, using a combination of macrovascular polytetrafluoroethylene (Goretex) grafting, reverse saphenous vein interposition, and vein-patch angioplasty, to facilitate microvascular free-tissue transfer.- - - - - - - - - - ranking = 1keywords = vascular disease (Clic here for more details about this article) |
5/6. Arterial fibrodysplasia causing occlusive vascular disease simulating primary vasculitis.We report a case of arterial fibrodysplasia causing vascular disease with ulceronecrotic lesions in lower extremities. The arteriography showed a beaded pattern in both arteries and veins; laboratory test findings were within normal value ranges; the biopsy reported medial hyperplasia involving the arterial and venous walls. Arterial fibrodysplasia should be considered as a differential diagnosis in patients complaining of recurrent occlusive vascular episodes without systemic manifestations, normal laboratory test results, and radiological patterns suggestive of fibrodysplasia. This is the first report of medial hyperplasia in digital arteries and venous wall involvement.- - - - - - - - - - ranking = 5keywords = vascular disease (Clic here for more details about this article) |
6/6. Concurrent infection due to shewanella putrefaciens and mycobacterium marinum acquired at the beach.infection with marine bacteria is uncommon. A patient with systemic lupus erythematosus who developed concurrent infection with shewanella putrefaciens and mycobacterium marinum (M. marinum) is described. After bathing leg ulcers in sea water, severe cellulitis of the left leg with necrotic areas and extensive bullae developed. infection due to S. putrefaciens was confirmed and a long course of hospitalization, oral ciprofloxacin and skin grafting was required. During hospitalization subcutaneous nodules developed on the other leg. biopsy revealed acid-fast bacilli and culture grew M. marinum. These lesions responded to rifampicin and cotrimoxazole. patients with leg ulcers, peripheral vascular disease, diabetes, or receiving immunosuppressive drugs may acquire unusual infections after salt water exposure.- - - - - - - - - - ranking = 1keywords = vascular disease (Clic here for more details about this article) |