1/8. fusobacterium necrophorum: a rare cause of meningitis in children.We report a case of non-fatal meningitis secondary to suppurative otitis media in a previously healthy young boy. fusobacterium necrophorum was isolated from blood; spinal fluid was cultured aerobically only but yielded no growth. After treatment with intravenous antibiotics and surgery the patient recovered, with a mild sequela of hypoglossus paresis.- - - - - - - - - - ranking = 1keywords = otitis (Clic here for more details about this article) |
2/8. Severe fusobacteria infections (lemierre syndrome) in two boys.Abscess formation is a rare cause of febrile illness in childhood but always has to be considered in such clinical presentations. Belonging to the resident flora of the oropharyngeal region, fusobacteria are known to cause local infections; from here they may extend to other sites via the bloodstream or are aspirated into the lung (Lemierre disease). We report on two boys with Lemierre disease due to infection by fusobacteria in monoculture causing two different clinical phenotypes. Case 1 presented with a large subphrenic abscess and pneumonic infiltration of the right middle lobe. Primary focus of infection was periodontal disease. Case 2 presented with a life-threatening septicaemia due to a retropharyngeal abscess and perforated otitis media followed by osteomyelitis of the atlas and thrombosis of the left sigmoid sinus and internal jugular vein. CONCLUSION: fusobacteria should be considered in any abscess formation in children. A thorough examination of the oropharyngeal region as a possible site of primary manifestation is mandatory.- - - - - - - - - - ranking = 1keywords = otitis (Clic here for more details about this article) |
3/8. Complicated otitis media caused by fusobacterium necrophorum.fusobacterium necrophorum is implicated as an aetiological agent in a variety of necrotic diseases, such as Lemierre's syndrome (LS) in humans. LS was initially described as septic thrombophlebitis of the internal jugular vein secondary to an acute oropharyngeal infection. Other primary sources of infection include parotitis, otitis media, sinusitis, odontogenic infection and mastoiditis. In the pre-antibiotic era LS carried a high mortality. This has been reduced as a result of the widespread use of antibiotics, but there is still a definite morbidity and mortality associated with infection with this virulent organism. We report three cases of complicated otitis media caused by fusobacterium necrophorum. The patients were treated successively with intravenous metronidazole and surgery.- - - - - - - - - - ranking = 7keywords = otitis (Clic here for more details about this article) |
4/8. meningitis due to fusobacterium necrophorum in an adult.BACKGROUND: fusobacterium necrophorum may cause a number of clinical syndromes, collectively known as necrobacillosis. meningitis is a significant cause of mortality, rarely reported in the adult population. CASE PRESENTATION: We report a fatal case of meningitis, caused by fusobacterium necrophorum, secondary to otitis media in an alcoholic male. diagnosis was delayed due to the typical slow growth of the organism. The clinical course was complicated by encephalitis and by hydrocephalus. The patient failed to respond to metronidazole and penicillin. The patient died on day 12 from increased intracranial pressure and brain stem infarction. CONCLUSIONS: This case emphasizes the need for a high index of clinical suspicion to make the diagnosis of fusobacterium necrophorum meningitis. We recommend the use of appropriate anaerobic culture techniques and antimicrobial coverage for anaerobic organisms when the gram stain shows gram negative bacilli.- - - - - - - - - - ranking = 1keywords = otitis (Clic here for more details about this article) |
5/8. Otogenic fusobacterium necrophorum meningitis.A case of meningitis secondary to acute suppurative otitis media in a previously healthy child is reported. The only organism isolated from blood after aerobic and prolonged anaerobic culture was identified as fusobacterium necrophorum. Complete recovery followed treatment with surgery and prolonged antibiotic therapy. The role of anaerobes in the development of meningitis, the isolation and identification of fusobacterium necrophorum, the clinical presentations of F. necrophorum infection and the choice of antibiotics in the treatment of these infections are discussed.- - - - - - - - - - ranking = 1keywords = otitis (Clic here for more details about this article) |
6/8. Acute suppurative parotitis caused by anaerobic bacteria: report of two cases.staphylococcus aureus is the predominant pathogen in acute suppurative parotitis. Although anaerobic bacteria are prevalent in the normal oral and upper respiratory tract flora and frequently are involved in oral and facial infections, they have seldom been isolated from patients with suppurative parotitis. It may be that a role for anaerobes in parotitis has not been documented because of inadequate specimen transport or anaerobic culture techniques. We describe two cases of acute suppurative parotitis in which cultures yielded anaerobic bacteria. In one case, no aerobes were isolated; in the other, the anaerobe was the predominant organism numerically.- - - - - - - - - - ranking = 8keywords = otitis (Clic here for more details about this article) |
7/8. Three cases of fusobacterium necrophorum septicemia.Two cases of necrobacillosis or post-anginal septicemia (Lemierre's syndrome) due to fusobacterium necrophorum are described. The first case in a young adult was complicated by thrombophlebitis of the internal jugular vein, lung abscesses and skin involvement. The second case was in a 2-year-old child, which is exceptional. The primary focus was possibly otitis media. In a third patient with multiple metastases of colon carcinoma, fusobacterium necrophorum septicemia was diagnosed during a bout of fever 36 hours before death.- - - - - - - - - - ranking = 1keywords = otitis (Clic here for more details about this article) |
8/8. Necrobacillosis: an unusual cause of purulent otitis media and sepsis.Necrobacillosis is a rare systemic illness caused by the anaerobic gram-negative bacterium, fusobacterium necrophorum. We describe a case of necrobacillosis in a previously healthy child who developed purulent otitis media with sepsis caused by F. necrophorum. This case demonstrates that not all cases of purulent ear drainage are caused by the usual otopathic organisms and emphasizes the importance of culturing ear discharge in a child with an unusual presentation.- - - - - - - - - - ranking = 5keywords = otitis (Clic here for more details about this article) |