1/15. Laser surgery in gynecology.More experience and time are required to determine the advantages of laser surgery in gynecology. For precision surgery through the colposcope, the carbon dioxide laser beam appears to be useful in the control of neoplastic lesions of the vaginal mucosa and possibly of the cervix uteri. Tumor volume reduction through laser vaporization, especially when a recurrent tumor is attached to the bony pelvis, is an outstanding advantage. Adhesiolysis during myomectomy and reconstructive surgery of the fallopian tubes might be facilitated by the laser beam. Laser surgery on the vulva, both colposcopically directed and grossly with the CO2 laser scalpel, might prove to be important for the treatment of various lesions. Detailed technical knowledge, rigid safety precautions, and judicious clinical considerations are essential for competent laser surgery.- - - - - - - - - - ranking = 1keywords = mucosa (Clic here for more details about this article) |
2/15. Ligneous (pseudomembranous) inflammation involving the female genital tract associated with type-1 plasminogen deficiency.Ligneous (pseudomembranous) inflammation of the female genital tract is a rare and unusual condition characterized by extensive subepithelial fibrin deposition and associated inflammation. Ligneous inflammation in extragenital sites, predominantly the conjunctiva, has been linked to plasminogen deficiency. Individuals with plasminogen deficiency are unable to remove fibrin deposited in injured mucosal tissue. Severe systemic ligneous inflammation involving the female genital tract that is linked to hypoplasminogenemia has not previously been described. We present a patient with ligneous inflammation of her genital, middle ear, and oral mucosa that was associated with type-1 homozygous plasminogen deficiency due to a novel missense mutation in the plasminogen gene.- - - - - - - - - - ranking = 2keywords = mucosa (Clic here for more details about this article) |
3/15. Fulminant neonatal sepsis due to haemophilus influenzae.A case of fulminant neonatal haemophilus influenzae sepsis is presented. A 29-year-old woman presented at 34 weeks gestation with premature labor but with intact membranes. The male infant died 8 h after delivery due to respiratory insufficiency. Ante-mortem blood cultures and post-mortem blood and lung cultures yielded H. influenzae (biotype II) which could not be serotyped. H. influenzae was cultured from the mother's cervix 5 days after delivery. This strain was of the same biotype and also nonserotypable. serum obtained from the mother exhibited reduced bactericidal activity against the isolates. We suggest the use of selective media in routine cervix cultures from pregnant women to detect H. influenzae, which might be responsible for neonatal septicemia.- - - - - - - - - - ranking = 0.037114682608206keywords = membrane (Clic here for more details about this article) |
4/15. Improved laser techniques for the elimination of genital and extragenital warts.Two series of patients with genital warts were compared for effectiveness of treatment by means of the carbon dioxide laser. In the earlier series (1977 to 1981) laser vaporization was used to remove overt warts while surrounding normal skin was spared. Examination of anal, urethral, and other extragenital sites for possible involvement was done only when warts persisted or recurred. In the later series (1983 to 1985), patients were similarly treated by carbon dioxide laser techniques; however, two additional measures supplemented laser vaporization of gross condyloma acuminatum. The brush technique superficially coagulated skin and mucosal surfaces contiguous to warts. This methodology was hypothesized to eliminate subclinical human papillomavirus infection within normal-appearing epithelium. Compulsive examination and treatment of extragenital sites at the time of the initial laser surgical procedure eliminated the most likely locations for persistence or recurrence. The primary cure rate for the earlier series was 65.8% compared to 91% for the later series. This difference was highly significant (p less than 0.005).- - - - - - - - - - ranking = 1keywords = mucosa (Clic here for more details about this article) |
5/15. diagnosis and surgical treatment of colonic endometriosis.endometriosis is sufficiently common that it should always be considered in the differential diagnosis of colon lesions of women of childbearing age. Seven selected cases illustrate problems in diagnosis and management of endometriosis of the colon. Characteristic of colon endometriosis are large bowel symptoms frequently associated with gynecologic complaints, usual sigmoid and rectosigmoid location, extramucosal radiologic appearance, and difficult diagnosis by endoscopic biopsy. Suspicion of malignancy and presence of a symptomatic colon lesion are indications for bowel resection, which is an effective form of therapy.- - - - - - - - - - ranking = 1keywords = mucosa (Clic here for more details about this article) |
6/15. Acute febrile neutrophilic dermatosis with genital involvement.More than 80 cases of acute febrile neutrophilic dermatosis have been published since Sweet in 1964 described the syndrome. Besides skin eruptions, some patients have mucous membrane lesions involving mouth and lips. This report describes a patient with a pustular eruption consistent with Sweet's syndrome, who is believed to be the first with involvement of genital mucosa.- - - - - - - - - - ranking = 1.0371146826082keywords = mucosa, membrane (Clic here for more details about this article) |
7/15. malacoplakia of the cervix and corpus uteri: a light microscopic, electron microscopic, and X-ray microprobe analysis of a case.malacoplakia in the female genital tract is rare. A case of a 71-year-old woman with malacoplakia of the cervical mucosa and endometrium is described. By light microscopy, von Hansemann cells containing calcified bodies (Michaelis-Gutmann bodies) could be visualized. Similar formations could also be seen extracellularly. Typical Michaelis-Gutmann bodies with electron-dense areas, as well as with pale centers and a dark periphery, could be identified by electron microscopy. Occasional trilaminar bacteria were seen. X-ray microanalysis indicated the presence of silica, sulfur, chloride, calcium, magnesium, and iron. malacoplakia in this region may cause diagnostic problems for the pathologist, but the presence of a monotonous tumor-like infiltrate of pale histiocytes should lead to a careful search for Michaelis-Gutmann bodies.- - - - - - - - - - ranking = 1keywords = mucosa (Clic here for more details about this article) |
8/15. Anaerobic infections of the pelvis.In normal nonpregnant women anaerobes predominate in the cervicovaginal flora. The frequency of bacteroides fragilis isolation ranges up to 16%. In pregnancy anaerobic prevalence falls progressively from the first to the third trimester and increases precipitously immediately after delivery. Anaerobes are often responsible for infections from vulva to ovaries, but the microbial etiology of post-cesarean section endometritis remains unclear. risk factors for pelvic infection include cesarean delivery as contrasted with vaginal delivery; among those undergoing cesarean section, risk factors for infection are prolonged labor, prolonged membrane rupture, excessive numbers of vaginal examinations, and perhaps age of less than 17 years. gonorrhea is also a risk factor for subsequent pelvic infection. The use of an intrauterine contraceptive device is associated with increased risk of pelvic actinomycosis. Anaerobic disease often is associated with a putrid odor and may present as 1 or more pulmonary emboli. Optimal treatment of pelvic anaerobic infections is not yet agreed upon. clindamycin and chloramphenicol are the 2 documented first-line agents. Penicillin is often effective but a substantial percentage of B fragilis strains resist it; this is also true of carbenicillin. The data on cefoxitin look encouraging, but more data are needed on both the efficacy and the frequency of superinfection.- - - - - - - - - - ranking = 0.037114682608206keywords = membrane (Clic here for more details about this article) |
9/15. Upper airway and external genital involvement in epidermolysis bullosa dystrophica.Radiographic findings in two patients with uncommon manifestations of epidermolysis bullosa dystrophica are described. A girl with recurrent urinary tract infections had scarring of the external genitalia producing chronic vaginal and uterine reflux and retention of urine. A second patient with long-standing stridor was found to have subglottic narrowing due to localized subglottic edema associated with an inflammatory membrane. The second case illustrates the occasional involvement of columnar epithelial surfaces which can occur in both epidermolysis bullosa dystrophica and epidermolysis bullosa hereditaria letalis.- - - - - - - - - - ranking = 0.037114682608206keywords = membrane (Clic here for more details about this article) |
10/15. Ascending transcervical herpes simplex infection with intact fetal membranes.A case of herpes simplex infection in the placenta and in an immature infant delivered to a mother with proved genital herpes infection is discussed. Infection occurred without premature rupture of membranes. Viral transmission could be attributed to ascending transcervical infection based on evidence of necrotizing chorioamnionitis in absence of villitis plus extensive and severe involvement of the skin and lungs. Such distinct documentation of transcervical infection in the presence of intact fetal membranes makes it obvious that delivery by cesarean section cannot prevent all cases of neonatal herpes infection.- - - - - - - - - - ranking = 0.22268809564923keywords = membrane (Clic here for more details about this article) |
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