Cases reported "Genital Neoplasms, Male"

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1/31. Malignant fibrous histiocytoma of the spermatic cord: a case report.

    We present a case of malignant fibrous histiocytoma of the spermatic cord. An 86-year-old man was admitted to the hospital with a right painless scrotal mass. Under the diagnosis of a testicular tumor, right radical orchiectomy was performed. Grossly, the tumor firmly adhered to the spermatic cord. The right testis and epididymis were normal. The histologic diagnosis was malignant fibrous histiocytoma. There was local recurrence 2 months after surgery. The recurrent tumor was resected with the surrounding soft tissue, but the patient died 5 months after the initial operation.
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keywords = histiocytoma
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2/31. Venous hemangioma of the scrotum: a case report.

    We report a case of intrascrotal hemangioma. A 68-year-old man who had noticed a swelling in his left scrotum over the past 1 year was seen at our hospital. Under a diagnosis of intrascrotal tumor, total excision of the mass was performed. Histopathological examination revealed venous hemangioma of the scrotum.
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ranking = 0.0039790079386229
keywords = hemangioma
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3/31. Malignant fibrous histiocytoma of the right spermatic cord: a case report.

    The patient was a 47-year-old male, who visited Hidaka Hospital with a chief complaint of swelling in the right inguinal region and the scrotum. With a diagnosis of a right spermatic cord tumor, right high orchiectomy was performed. Since an inflammatory type of malignant fibrous histiocytoma (MFH) was diagnosed from histopathological findings, chemotherapy and radiation therapy were performed as postoperative treatment. Malignant fibrous histiocytoma with the primary focus of the spermatic cords is a rare disease. To our knowledge, this is the 20th case of MFH of the spermatic cord in japan (the 42nd in the world) and it is the second case of inflammatory type of MFH in japan.
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keywords = histiocytoma
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4/31. Megapenis associated to corpus spongiosum agenesis with scrotal and pelvic hemangiomas.

    An exceptional case of megapenis associated with corpus spongiosum agenesis and multiple hemangiomas of the scrotum, perineum and pelvis is reported. This is the first case in which three exceptional malformations are associated.
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ranking = 0.0033158399488524
keywords = hemangioma
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5/31. Malignant fibrous histiocytoma of the spermatic cord: report of two cases and review of the literature.

    Malignant fibrous histiocytoma (MFH) of the spermatic cord is rare, and most published cases are single case reports that emphasize clinical presentation and management. We describe in detail the histopathologic features of 2 cases of high-grade storiform-pleomorphic MFH arising in the spermatic cord. Both tumors occurred in elderly men, 65 years and 70 years, and were 4 cm (Case 1) and 5 cm (Case 2) in greatest dimension. The tumor mass in Case 1 was associated with satellite tumor nodules. At last follow-up, in Case 1 the patient died of metastasis, and in Case 2, the patient is alive and well 46 months after diagnosis. review of the literature reveals 33 additional cases published in English (17 cases) or Japanese (16 cases) that include histologic description. Including the 2 cases in this report, most of the tumors occurred in older (than 50 years) patients (28 of 35 cases, 80%) and occurred as solitary masses that ranged in diameter from less than 1 cm to more than 20 cm. Nine patients presented with satellite tumor nodules. Twenty-nine (83%) tumors were of the storiform-pleomorphic type, with 3 giant cell type, 2 inflammatory type, and 1 myxoid type. These features do not differ significantly from MFH in other anatomic sites. Clinical follow-up is available in 33 cases (3-174 months; mean, 31.5 months). Twelve patients developed recurrence and metastasis; at least 4 patients died of the disease. Tumor size does not predict the clinical progression; however, patients with progressive tumors were commonly associated with satellite nodules at time of presentation, an indication of early local metastasis.
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ranking = 0.83333333333333
keywords = histiocytoma
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6/31. Cavernous hemangioma of spermatic cord: report of a case with immunohistochemical study.

    We present a case of spermatic cord cavernous hemangioma. A 32-year-old man presented with a circumscribed, painless mass in the left side of the spermatic cord. An orchiectomy of the left testicle was performed. A 3 x 3 x 2.5-cm mass was present in the spermatic cord area. Histologic examination and immunohistochemical study showed a benign vascular tumor composed of vascular spaces of varying size. Although cavernous hemangioma can occur in any location, the spermatic cord is an extremely rare site, and, to our knowledge, only a few cases have been previously reported.
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ranking = 0.0039790079386229
keywords = hemangioma
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7/31. Intrascrotal hemangioma.

    Although hemangiomas are the most common benign tumors in infancy, scrotal hemangiomas are extremely rare and comprise less than 1% of all hemangiomas. Scrotal hemangiomas that extend into adjacent areas of the perineum, thigh, or anterior abdominal wall may occasionally be seen. Ultrasound is recommended as part of the preoperative assessment delineating the extent of a scrotal hemangioma. Since an absence of flow on Doppler studies does not exclude the diagnosis of hemangioma, MRI (magnetic resonance imaging) may provide more useful information for differentiation. In cases of cutaneous scrotal hemangiomas, conservative treatment that waits for involution is widely accepted. In patients with scrotal masses, exploration with excision is the treatment of choice even if a hemangioma is likely. The authors report a case of an intrascrotal tumor diagnosed preoperatively by color duplex ultrasonography and MRI in a 19-year-old male who subsequently underwent en bloc excision. Pathological examination identified a cavernous hemangioma.
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ranking = 0.0086211838670162
keywords = hemangioma
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8/31. liposarcoma with meningothelial-like whorls. Report of four cases showing diverse histologic findings and behavior.

    We report the clinicopathologic findings of four cases of liposarcoma with meningothelial-like whorls. Two cases occurred in the retroperitoneum and the remaining cases in the anterior mediastinum and scrotum. The whorls varied in terms of amount and morphology and the type tissue surrounding the whorls also varied in every case. One of the retroperitoneal cases with large areas of whorl coalescence recurred in the abdominal wall as an inflammatory malignant fibrous histiocytoma one year after primary resection of the tumor, and a metastasis to the cervical spines was detected twenty months later. The other retroperitoneal tumor recurred locally two years after the resection of the tumor and the amount and cellularity of the whorls as well as p53 reactivity and Ki-67 labeling index were higher in the recurrent tumor. However, coalescence of the whorls was not present in the recurrent tumor in contrast to the primary tumor. The anterior mediastinal and scrotal cases have demonstrated neither local recurrence nor distant metastasis although the follow-up period has been less than one year. The cells comprising whorls showed positive reactions for CD10, CD56, CD99, factor XIII, and low-affinity nerve growth factor receptor in addition to vimentin and alpha-smooth muscle actin. Our results indicate that liposarcoma with meningothelial-like whorls is a heterogeneous group that shows wide variations in histologic findings and biologic behavior. The phenotypic transformation of the whorls to higher grade in two retroperitoneal tumors, which showed recurrence within two years of follow up, supports that a whorl is a sign of dedifferentiation. Although we demonstrate the expressions of several markers, such as CD10, CD56, CD99, factor XIII, and low-affinity nerve growth factor receptor, in the spindle cells of the whorls for the first time, the lineage of the whorls still cannot be addressed due to the fact that these markers are lineage nonspecific.
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ranking = 0.16666666666667
keywords = histiocytoma
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9/31. Atypical fibrous histiocytoma of the scrotum.

    Atypical fibrous histiocytoma is a rare neoplasm. A scrotal location for this tumor is even more unusual. We report a case of a 90-year-old man with scrotal atypical fibrous histiocytoma. Our case had histologic features consistent with those cases previously reported in the literature. The tumor consists of cells with large hyperchromatic irregular nuclei, bizarre multinucleated cells (monster cells), and xanthomatous cells with large prominent nuclei set in a background of classic fibrous histiocytoma. Rare mitotic figures are identified. Immunohistochemical studies showed the tumor cells to be positive for vimentin, smooth muscle actin, desmin, KP-1, factor xiiia, and MIB-1 (less than 10%). In addition to the expected immunohistochemical studies, the tumor stained diffusely positive for CD117. To our knowledge, this is the first report of atypical fibrous histiocytoma of the scrotum.
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ranking = 1.3333333333333
keywords = histiocytoma
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10/31. Malignant fibrous histiocytoma of the spermatic cord.

    Malignant fibrous histiocytoma (MFH) of the spermatic cord is rare. However, owing to its location it is diagnosed early and has a better prognosis. A case of MFH of the spermatic cord is reported in a 50-year-old male along with review of the literature, discussing the recommended management and prognosis of this condition and emphasising upon its clinical recognition since the prognosis and management are different from the MFH, in general.
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ranking = 0.83333333333333
keywords = histiocytoma
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