1/28. Peripheral giant cell granuloma: a potentially aggressive lesion in children.A slowly enlarging gingival mass with a reddish-purple surface is observed in a school-age boy. The lesion was first noted 3 months ago during a routine oral examination but recently it has increased in size and interferes with eating. A periapical radiograph demonstrated focal loss of the alveolar crestal bone in the mandibular incisor region. The diagnosis of peripheral giant cell granuloma, a benign reactive gingival lesion, is confirmed by histopathologic examination. Early detection and excision of this hyperplastic nodule is important to minimize potential dentoalveolar complications.- - - - - - - - - - ranking = 1keywords = giant (Clic here for more details about this article) |
2/28. Peripheral giant cell granuloma--a case report.Peripheral giant cell granuloma is a lesion arising mainly from the connective tissue of gingiva or periosteum of alveolar ridge. A case of peripheral giant cell granuloma involving a deciduous molar and the succedaneous tooth is reported. The lesion was large and interfered with occlusion. Surgical excision of the lesion along with the deciduous first molar was done. The underlying permanent first premolar was also involved, and had to be removed. The importance of an adequate salivary flow and maintenance of oral hygiene in the prevention of such lesions is stressed.- - - - - - - - - - ranking = 1.2keywords = giant (Clic here for more details about this article) |
3/28. Peripheral giant cell granuloma: three case reports.Three cases of peripheral giant cell granuloma (PGCG) with histopathological and long-term evaluations are presented. In all the cases that were all female and ages ranged between 5.5 to- 12 years, after complete surgical excision of the lesion no recurrence was detected during a follow-up period of 2 to 4 years. Although etiological factors could not be determined exactly, low socioeconomic status of the patients and unfavorable oral hygiene seemed to be the predisposing factors.- - - - - - - - - - ranking = 1keywords = giant (Clic here for more details about this article) |
4/28. Long-term follow-up of peripheral ossifying fibroma: report of three cases.Peripheral ossifying fibroma is a non-neoplastic enlargement of the gingiva that is classified as a reactive hyperplastic inflammatory lesion. It is possible to misdiagnose peripheral ossifying fibroma as pyogenic granuloma, peripheral giant cell granuloma, or odontogenic tumors. Therefore, histopathological examination is essential for an accurate diagnosis of such lesions. Differential diagnosis is important, because peripheral ossifying fibroma has a tendency to recur. This article describes three cases of peripheral ossifying fibroma, which were followed for 4 years without any sign of recurrence. By presenting these cases, we emphasize the importance of proper excision and aggressive curettage of the adjacent tissues for prevention of recurrence.- - - - - - - - - - ranking = 0.2keywords = giant (Clic here for more details about this article) |
5/28. Polishing-paste-induced silica granuloma of the gingiva.Polishing-paste-induced silica granuloma of the gingiva, an uncommon condition, may mimic various local or systemic pathological entities. A 33-year-old woman and a 42-year-old man were referred for a localised refractory gingival inflammation. Clinical diagnoses included allergy, lichen planus and herpes. biopsy showed well-demarcated non-caseating granulomas, associating epithelioid and Langhans giant cells. Special bacterial and mycological stains were negative. Systemic examination and laboratory tests ruled out sarcoidosis and Crohn's disease. Polarised light revealed birefringent crystalline foreign material. A diagnosis of silica granuloma was made. Both patients had frequent dental hygiene treatment including polishing with abrasive paste, suggesting an iatrogenic implantation of the foreign bodies. Gingival damage can result from the use of some dental materials containing silica. Often asymptomatic, sometimes producing visible lesions, granulomatous gingivitis may mislead into wrong diagnosis and treatment. Old silica granulomas may become symptomatic if the patient contracts sarcoidosis.- - - - - - - - - - ranking = 0.2keywords = giant (Clic here for more details about this article) |
6/28. Peripheral giant cell granuloma: a case report.The peripheral giant cell granuloma is a reactive lesion of the soft tissue of the oral cavity. Clinical appearance ranges from normal tissue coloration to dark red or purplish. These are elevated lesions generally 5-15 mm in diameter. Etiology is considered to be chronic irritation. To decrease the risk of clinical recurrence, treatment is complete excision to include the underlying periosteum. Histologic features of the peripheral giant cell granuloma include multinucleated giant cells with a stroma that may contain osteoblasts, myofibroblasts, macrophages, and langerhans cells. A case report is presented.- - - - - - - - - - ranking = 1.4keywords = giant (Clic here for more details about this article) |
7/28. Pyogenic granuloma: case report in a 9-year-old girl.Based on clinical features alone, pyogenic granuloma can be difficult to differentiate from a peripheral giant cell granuloma, a more aggressive oral lesion that could have consequences such as teeth displacement and alveolar bone resorption. A thorough clinical and radiographic examination is important to determine whether teeth and/or bone are involved. Furthermore, the early onset of puberty in females may increase the prevalence of pyogenic granuloma at a young age.- - - - - - - - - - ranking = 0.2keywords = giant (Clic here for more details about this article) |
8/28. Multiple and synchronous peripheral giant cell granulomas of the gums.The presence of multiple giant cell lesions in the maxillofacial region is suggestive of hyperparathyroidism or neurofibromatosis. A case of synchronous, multiple peripheral giant cell granulomas is reported, bilaterally affecting the mandibular gums and also the upper right maxillary gingival mucosa, without concomitant systemic disease. Only 2 cases of central giant cell granulomas, and no cases of peripheral giant cell granulomas exhibiting similar characteristics, have been reported in the literature to date.- - - - - - - - - - ranking = 1.6keywords = giant (Clic here for more details about this article) |
9/28. bernard-soulier syndrome in a Turkish family.This report describes the first Turkish family to be diagnosed with bernard-soulier syndrome. The family consists of nine members (two parents, three sons and four daughters). The parents were first cousins. The index case, a 22 year-old-man, had a history of haemorrhagic diathesis with thrombocytopenia, giant platelets in the peripheral blood smear and a prolonged bleeding time. Refractory idiopathic thrombocytopenic purpura had been diagnosed elsewhere and a splenectomy had been performed six months previously. ristocetin agglutination of platelets was defective and flow cytometry analysis of platelet membrane glycoprotein showed markedly reduced expression of glycoprotein lb (2.1%). bernard-soulier syndrome was diagnosed. Increased mean platelet volume was found in both parents, one son and three daughters. The other son and daughter were normal.- - - - - - - - - - ranking = 0.2keywords = giant (Clic here for more details about this article) |
10/28. Histopathological characteristics of eruption mesenchymal calcified hamartoma: two case reports.Odontogenic calcified masses were present in the opercula of lower first molars that were delayed in eruption. The masses were relatively small, opaque, white in color with a smooth texture. Histopathological examinations revealed that they contained osteodentin, cementum, and pulp-like components; however, not odontogenic epithelial cells or enameloid. Further, mesenchymal multinucleated giant cells and dysplastic dental matrices were observed in the connective tissues surrounding the masses. These clinical and histopathological findings disagree with the features of pericoronal odontogenic hamartoma lesions, including odontoma, ameloblastic fibroma, and ameloblastic fibro-odontoma. Therefore, we propose to categorize this odontogenic mass as a new variety of hamartoma, eruption mesenchymal calcified hamartoma.- - - - - - - - - - ranking = 0.2keywords = giant (Clic here for more details about this article) |
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