1/7. Gingival plasma cell granuloma.Plasma cell granulomas (pseudotumors) are rare benign, tumor-like proliferations composed chiefly of plasma cells that manifest primarily in the lungs, but may occur in various anatomic locations. We report this case of a 54-year-old male who presented with an unusual maxillary anterior gingival overgrowth treated by excisional biopsy. Histological examination revealed a dense inflammatory cell infiltrate containing mainly plasma cells. immunohistochemistry for kappa and lambda light chains showed a polyclonal staining pattern confirming a diagnosis of plasma cell granuloma. Intraoral plasma cell granuloma is exceedingly rare, although case reports documenting such lesions have been reported. This case highlights the need to biopsy unusual lesions to rule out potential neoplasms.- - - - - - - - - - ranking = 1keywords = neoplasm (Clic here for more details about this article) |
2/7. Undifferentiated malignant neoplasm involving the interdental gingiva: a case report.BACKGROUND: Metastases to the gingiva are uncommon. They can be a diagnostic challenge clinically because of their rarity and tendency to mimic benign lesions. In this report, we present a case of an undifferentiated malignant neoplasm of unknown origin presenting as benign inflammatory gingival lesions and we review the literature on metastases to the gingiva. methods: A 44-year-old female patient was referred by a local periodontist for evaluation of multiple painless gingival lesions that clinically resembled pyogenic granulomas or periodontal abscesses, but with an uncharacteristic multifocal presentation in the background of good oral hygiene. Her medical history was unremarkable except for recent weight loss. Periapical radiographs were obtained, as well as two incisional biopsies, one placed in formalin for routine histology and immunohistochemistry, the other in phosphate buffered saline for flow cytometry. RESULTS: Radiographic findings were non-contributory for hard tissue pathoses. Histopathological findings were consistent with a poorly differentiated malignancy, suggestive of metastatic disease. Immunohistochemical studies and flow cytometry were unsupportive in delineating any tumor differentiation. The patient subsequently developed multiple tumors throughout the body with similar histopathological findings, yet no primary tumor was identified and a definitive diagnosis could not be rendered. She was discharged one month later in poor condition with the principal diagnosis of hemorrhage/ pancytopenia, and a secondary diagnosis of metastatic head and neck cancer. CONCLUSION: This case of malignant metastatic tumor of unknown origin presenting as benign gingival lesions illustrates the importance of thorough patient evaluation, which should include a biopsy when necessary for definitive diagnosis.- - - - - - - - - - ranking = 5keywords = neoplasm (Clic here for more details about this article) |
3/7. Plasma cell granuloma of gingiva.An exceedingly rare case of gingival plasma cell granuloma is reported in a 40-year old female patient. The case presented as an exophytic mass of gingiva, clinically resembling traumatic fibroma. Histopathologic findings revealed dense sheets of plasma cells infiltrate. immunohistochemistry for kappa and lambda light chains showed polyclonal (benign) staining pattern confirming a diagnosis of plasma cell granuloma. It is important to recognise this peculiar lesion because of its highly unusual incidence in involving the periodontium. Clinical features are usually suggestive of traumatic fibroma (benign) but histopathologicaly in early stages it closely resembles plasmacytoma (malignant). This case highlights the need to biopsy unusual lesions to rule out potential neoplasms and also emphasizes the need to submit all the excised tissue for histological examination regardless of clinical impression and/or perceived surgical success. Only by such practice can rare lesion of this type be diagnosed and their incidence studied.- - - - - - - - - - ranking = 1keywords = neoplasm (Clic here for more details about this article) |
4/7. Pyogenic granuloma associated with bone loss in an eight year old child: A case report.Soft tissue enlargements of the oral cavity often present a diagnostic challenge because a diverse group of pathologic processes can produce such lesions. An enlargement may represent a variation of normal anatomic structures, inflammation, cysts, developmental anomalies and neoplasm. Within these lesions is a group of reactive hyperplasias, which develop in response to a chronic, recurring tissue injury that stimulates an exuberant or excessive tissue repair response. The pyogenic granuloma is a reactive enlargement that is an inflammatory response to local irritation such as calculus, a fractured tooth, rough dental restoration and foreign materials. This article aims to present a case of pyogenic granuloma in 8 year old child patient associated with resorption of bone in relation to the tooth.- - - - - - - - - - ranking = 1keywords = neoplasm (Clic here for more details about this article) |
5/7. Infected suture granuloma: a case report.Suture granulomas mimic neoplasms in clinical appearance and may increase in frequency as dental implant therapy increases. This case report illustrates the clinical and histologic features of this sometimes perplexing postoperative complication.- - - - - - - - - - ranking = 1keywords = neoplasm (Clic here for more details about this article) |
6/7. An unusual epithelial neoplasm of gingiva resembling the keratoacanthoma.An unusual, tumour-like mass protruding from labial and palatal gingivae and surrounding the unerupted canine in a 12-year-old child is described. Clinically, the lesion was felt to be aggressive but histologically, the most likely diagnosis was keratoacanthoma, probably of the nodulovegetating type. Following excision of the mass, healing has been uneventful. Whether or not the histological diagnosis of keratoacanthoma is accepted, rather than an unusual odontogenic neoplasm, this case illustrates the existence of an entity comprising well-differentiated islands and cysts of squamous epithelium with a rapid growth pattern.- - - - - - - - - - ranking = 5keywords = neoplasm (Clic here for more details about this article) |
7/7. The peripheral ameloblastoma of the gingiva. Case report and literature review.A new case of the rare peripheral ameloblastoma of the gingiva is presented. Also the clinical and histomorphologic characteristics of the lesion were analyzed and studied in all previously documented cases. This tumor, and the basal cell carcinoma of the gingiva, probably represent the same lesion. It meets the same microscopic criteria as the intraosseous ameloblastoma, but its behavioral and clinical characteristics are completely different. The peripheral ameloblastoma usually occurs in the gingiva, is noninvasive, and local excision is usually curative. recurrence of the neoplasm is uncommon, except when it is incompletely excised. The histogenesis and varied cellular pattern of the peripheral ameloblastoma and several other related odontogenic lesions of the gingiva illustrate the proliferative and differentiation potential of the basal cell layer of gingival epithelium.- - - - - - - - - - ranking = 1keywords = neoplasm (Clic here for more details about this article) |