1/14. Peripheral giant cell granuloma: a potentially aggressive lesion in children.A slowly enlarging gingival mass with a reddish-purple surface is observed in a school-age boy. The lesion was first noted 3 months ago during a routine oral examination but recently it has increased in size and interferes with eating. A periapical radiograph demonstrated focal loss of the alveolar crestal bone in the mandibular incisor region. The diagnosis of peripheral giant cell granuloma, a benign reactive gingival lesion, is confirmed by histopathologic examination. Early detection and excision of this hyperplastic nodule is important to minimize potential dentoalveolar complications.- - - - - - - - - - ranking = 1keywords = giant (Clic here for more details about this article) |
2/14. Myxoid liposarcoma of the oral cavity with involvement of the periodontal tissues.BACKGROUND, AIMS: liposarcoma is the 2nd most frequent soft tissue sarcoma in adults, but it is extremely rare in the head and neck and, particularly, in the oral cavity. We report on a 25-year-old female who presented with a periodontal mass, extended from the right upper 3rd molar to the right upper 2nd premolar, covered by intact oral mucosa. The clinical differential diagnosis included peripheral giant cell granuloma, salivary gland neoplasms, squamous cell carcinoma of the gingiva, sarcoma and malignant lymphoma. methods: To accurately plan subsequent treatment, an excisional biopsy was performed and a myxoid liposarcoma was diagnosed. Consequently, the patient underwent wide excision of the neoplasm with maxillary en-block resection. RESULTS: The post-operative course was uneventful and the patient is alive and well 8 years after the original diagnosis. The authors stress the importance of considering soft tissue sarcomas in the diagnostic approach to patients with unusual periodontal neoplasms and to plan adequate surgical sampling of the lesion (i.e. excisional biopsy). CONCLUSIONS: This appears of pivotal importance as more limited specimens may result in inaccurate pre-operative diagnosis.- - - - - - - - - - ranking = 0.2keywords = giant (Clic here for more details about this article) |
3/14. Long-term follow-up of peripheral ossifying fibroma: report of three cases.Peripheral ossifying fibroma is a non-neoplastic enlargement of the gingiva that is classified as a reactive hyperplastic inflammatory lesion. It is possible to misdiagnose peripheral ossifying fibroma as pyogenic granuloma, peripheral giant cell granuloma, or odontogenic tumors. Therefore, histopathological examination is essential for an accurate diagnosis of such lesions. Differential diagnosis is important, because peripheral ossifying fibroma has a tendency to recur. This article describes three cases of peripheral ossifying fibroma, which were followed for 4 years without any sign of recurrence. By presenting these cases, we emphasize the importance of proper excision and aggressive curettage of the adjacent tissues for prevention of recurrence.- - - - - - - - - - ranking = 0.2keywords = giant (Clic here for more details about this article) |
4/14. Cemento-ossifying fibroma of mandibular gingiva: single case report.We report a case of a woman presenting a giant cementoossifying fibroma depending of the mandibular gingivae. The evolution of the process was 20 years. Cemento-ossifying fibroma is a relatively rare tumour classified between fibroosseous lesions. This lesion appears within the bone although in some occasions it involves the gingivae soft tissues, as the case we present. It is a slow-growing and well-defined tumorous lesion, because of this, it is considered as a benign lesion. The histologic findings alone may be similar to other pathologies such as osteoblastoma, low-grade osteosarcoma and particularly to fibrous dysplasia. An accurate diagnosis requires careful clinical, radiological and histological correlation in order to make an optimal treatment and an excellent outcome.- - - - - - - - - - ranking = 0.2keywords = giant (Clic here for more details about this article) |
5/14. Identification of a giant cell fibroma.Fibrous hyperplastic connective tissue lesions are common in the oral cavity and may be similar both clinically and histologically. A giant cell fibroma, a type of fibrous hyperplasia, was discovered during a preventive patient visit in the dental hygiene clinic at a Midwestern university. The patient, a 19-year-old female, presented with a dome-shaped lesion of normal mucosal color on the attached gingiva apical to tooth number 11. She was referred to the dental school for biopsy, which revealed fibrocollagenous connective tissue exhibiting large stellate fibroblasts. She returned after 10 months and was referred to the graduate periodontal department, where the lesion was removed. Several fibrous hyperplastic lesions can be considered in the differential diagnosis of giant cell fibroma. dental hygienists should be familiar with the different fibrous hyperplasias, noting lesions during the intra- and extra-oral examinations for further evaluation by the dentist.- - - - - - - - - - ranking = 1.2keywords = giant (Clic here for more details about this article) |
6/14. Peripheral ameloblastoma: a case report and review of the literature.Peripheral ameloblastoma is a rare, benign odontogenic tumor that histologically resembles an intraosseous ameloblastoma but develops in the soft tissues of the gingiva and mucosa and exhibits an innocuous clinical behavior. We report a case of a recurrent peripheral ameloblastoma in a 61-year-old man that presented as a painless swelling on the maxillary anterior labial attached gingiva. Clinical and histopathologic features of this lesion are discussed. The peripheral ameloblastoma should be included in the differential diagnosis of a gingival lesion clinically resembling any of the myriads of entities seen on the gingiva including a pyogenic granuloma, peripheral giant cell granuloma, or parulis/gumboil. We believe this case highlights the need for submitting excised tissue for microscopic examination.- - - - - - - - - - ranking = 0.2keywords = giant (Clic here for more details about this article) |
7/14. Giant cell fibroma: a case report.This article describes a case of giant cell fibroma in a 3-year-old boy, which is an uncommon age for this lesion. The cause of this pathology has not been determined. The lesion was excised by electro surgery and submitted to a histological exam, which confirmed the diagnosis. No recurrence was observed. Pediatric dentists should be capable to diagnose and treat this kind of lesion despite this lesion being an unusual pathology among children.- - - - - - - - - - ranking = 0.2keywords = giant (Clic here for more details about this article) |
8/14. Mixed testicular germ cell tumor presenting as metastatic pure choriocarcinoma involving the maxillary gingiva.Gingival metastases are infrequent and invariably associated with a widespread disease and a poor prognosis. Because of their unremarkable clinical appearance, they can be difficult to distinguish from more common gingival hyperplastic or reactive lesions, such as pyogenic granuloma, peripheral giant cell granuloma, and peripheral ossifying granuloma. We are reporting here an unusual case of a 36-year-old man with a mixed testicular germ cell tumor presenting as a metastatic pure choriocarcinoma involving the maxillary gingiva, extending from the first left premolar to the left second maxillary molar, mimicking a 'benign looking' gingival mass. Gingival metastases may be the first manifestation of a widespread metastatic disease and therefore particular attention must be paid to gingival lesions associated with atypical clinical symptoms and/or signs.- - - - - - - - - - ranking = 0.2keywords = giant (Clic here for more details about this article) |
9/14. Giant cell fibroma. A case presentation and review.The giant cell fibroma should be of special interest to the periodontist as its primary site of occurrence is on the gingival tissue. A case report of a large giant cell fibroma is followed by a review of this interesting oral tumor, including the controversy surrounding its classification as a separate entity.- - - - - - - - - - ranking = 0.4keywords = giant (Clic here for more details about this article) |
10/14. Giant cell fibroma of the oral mucosa. Report of a case with ultrastructural study.A case of giant cell fibroma of the oral mucosa found in a 3-year-old female is reported. The lesion was characterized histologically by the presence of numerous large stellate cells and multinucleated giant cells scattered in a loosely arranged collagen-background. The large stellate cells had a large hyperchromatic nucleus, while the cytoplasm was well demarcated and frequently the cells had dendritic-like processes. The multinucleated giant cells had similar morphology and occasionally resembled Langhans' giant cells. Ultrastructural examination suggested that the multinucleated giant cells in the lesion were unusual fibroblasts. This is the first reported case of oral giant cell fibroma in a Japanese patient.- - - - - - - - - - ranking = 1.2keywords = giant (Clic here for more details about this article) |
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