1/15. Necrotizing ulcerative periodontitis associated with severe congenital immunodeficiency in a prepubescent subject: clinical findings and response to intravenous immunoglobulin treatment.common variable immunodeficiency (CVID) is a rare multifactorial congenital disease of genetic origin caused by an impairment in the secretion of specific immunoglobulins. It manifests systemically through recurrent respiratory infections, gastrointestinal disorders and autoimmune diseases. oral manifestations may include gingivitis and lichenoid lesions with Wickham's striae. The treatment for CVID is supported by using intravenous infusion of immunoglobulins (IVIG) that allows for control of the disease and avoidance of recurrent opportunistic infections. This report presents a case of necrotizing ulcerative periodontitis (NUP) in a young patient with CVID, and correlates his periodontal status with systemic conditions before and after IVIG administration during 1 year of evaluation.- - - - - - - - - - ranking = 1keywords = periodontitis (Clic here for more details about this article) |
2/15. Benign mucous membrane pemphigoid--a case report.Benign mucous membrane pemphigoid (BMMP) is a relatively rare, chronic vesiculobullous disease. It frequently affects postmenopausal women, although cases have been reported in younger individuals. Benign mucous membrane pemphigoid has a predilection to affect multiple mucosal surfaces including the gingivae, hard and soft palate, alveolar ridge, nose, pharynx, gastrointestinal tract, genitalia and the conjunctiva. It is seen clinically as bullae or erosions on the mucosae or gingivae. The bullae rupture after 24-48 hours and the erosions heal within 7-14 days, sometimes with scar formation. Scarring frequently occurs with ocular mucosa involvement and may contribute to blindness. In order to make a diagnosis, the clinical features must be correlated with microscopic and immunopathological findings. Benign mucous membrane pemphigoid is treated with high doses of corticosteroids and immunosuppressive agents. This paper is a presentation of a case report in a 36-year-old woman.- - - - - - - - - - ranking = 1.5357642451868E-5keywords = alveolar (Clic here for more details about this article) |
3/15. Ecstasy related periodontitis and mucosal ulceration -- a case report.Methylenedioxymethamphetamine (MDMA) more commonly known as 'Ecstasy' is a widely used recreational drug. The oral and systemic effects associated with its use have been well documented. This paper highlights a previously unreported complication of MDMA use on the oral mucosa. MDMA periodontitis is illustrated with a case report and the local oral and systemic effects of MDMA use outlined.- - - - - - - - - - ranking = 1keywords = periodontitis (Clic here for more details about this article) |
4/15. Fusospirochetosis causing necrotic oral ulcers in patients with hiv infection.Under certain permissive circumstances, normally occurring fusiform bacteria and borrelia spirochetes can result in a symbiotic overgrowth that leads to necrotic oral ulcers (stomatitis), gingivitis, and periodontitis. These lesions are collectively known as oral fusospirochetosis and may be under-appreciated in patients with hiv infection and AIDS. Fusospirochetal oral ulcers in patients with hiv are often large, necrotic, and malodorous; they respond completely to penicillin. We report 3 patients with hiv infection and fusospirochetal ulcerative stomatitis and review the clinical presentation, microbiologic diagnosis, potential pathogenesis, and treatment of these lesions.- - - - - - - - - - ranking = 0.2keywords = periodontitis (Clic here for more details about this article) |
5/15. Complex oral manifestations of an hiv-seropositive patient.A complex manifestation of characteristic oral lesions occurring simultaneously in an hiv-seropositive patient is presented. Necrotizing ulcerative gingivitis (NUG), necrotizing ulcerative periodontitis (NUP), oral-facial herpes infection, pseudomembranous candidiasis and atypical oral ulceration are discussed. In spite of extremely low CD4 T-cell counts of 3 x 10(6)/L and lack of anti-retroviral therapy, an AIDS patient responded favourably to standard periodontal therapy. In the follow-up period of 3 months, no recurrence of any of the oral lesions initially present occurred and no special prophylactic regimes were needed to maintain oral health. This case illustrates that appropriate management of the oral manifestations contributes significantly to improvement of the quality of life of patients in the terminal stage of hiv-AIDS.- - - - - - - - - - ranking = 0.2keywords = periodontitis (Clic here for more details about this article) |
6/15. Molecular changes in the gingival epithelium associated with necrotizing ulcerative periodontitis: a case report.A case of necrotizing ulcerative periodontitis (NUP), the most severe inflammatory periodontal disorder caused by plaque bacteria, is shown. Clinically, the gingiva showed distinct signs of ulceration, and radiography revealed horizontal bone loss. Indirect immunofluorescence, carried out on frozen sections of tissue specimens obtained from the NUP lesion, exhibited clear expression of atypical keratin K19, particularly in basal cells, when compared to noninflamed gingiva. Moreover, NUP tissue showed extensive intraepithelial abundance for the basement membrane component laminin-1/10 and the extracellular matrix molecule tenascin. Strong expression of integrin subunit alphav and matrix metalloproteinase-13 in conjunction with interleukin 1-beta further discriminated NUP gingival epithelium from normal tissue. The results suggest that NUP is associated with changes in the expression and topography of the analyzed molecules in the gingival epithelium, which in turn may reflect the fast progression of the disease.- - - - - - - - - - ranking = 1keywords = periodontitis (Clic here for more details about this article) |
7/15. Necrotizing gingivitis of Kaposi sarcoma affected gingivae.Necrotizing gingivitis and oral Kaposi sarcoma are common concomitants of hiv infection and both are regarded as indicators of hiv infection. Their simultaneous appearance in an hiv seropositive subject therefore, should be relatively common; but other reports documenting such cases could not be found. This article documents an uncommon case of necrotizing gingivitis superimposed on Kaposi sarcoma-affected gingiva, occurring in a patient with chronic periodontitis. The nature of necrotizing gingivitis and Kaposi sarcoma and the possible differential diagnosis of the periodontal attachment loss are discussed.- - - - - - - - - - ranking = 0.2keywords = periodontitis (Clic here for more details about this article) |
8/15. Oro-antral fistula: an unusual complication of hiv-associated periodontal disease.Oral lesions have been reported frequently in patients seropositive for human immunodeficiency virus. A case is reported of hiv-associated periodontitis complicated by necrotising stomatitis and the development of an oro-antral fistula; the role of extractions in the management of this condition is highlighted.- - - - - - - - - - ranking = 0.2keywords = periodontitis (Clic here for more details about this article) |
9/15. Progressive osseous destruction as a complication of hiv-periodontitis.A pathologic condition is described, characterized by rampant necrosis of gingival mucosa, periodontium, and related osseous structures associated with systemic infection with the human immunodeficiency virus (hiv). It is believed that this condition is an extension beyond the normal clinical course of hiv-periodontitis (hiv-P) and manifests itself in three progressive stages: (1) hiv-associated gingivitis, (2) hiv-P, and (3) an extension of hiv-P to osseous necrosis. Two cases of osseous destruction attending hiv-P are reported, one of which led to initial diagnosis of hiv infection. They represent the final stage of disease progression with localized necrosis of gingiva, periodontium, and alveolar bone.- - - - - - - - - - ranking = 1.0000153576425keywords = periodontitis, alveolar (Clic here for more details about this article) |
10/15. hiv-associated periodontitis complicated by necrotizing stomatitis.This report describes a case of hiv-associated periodontitis complicated by necrotizing stomatitis in a homosexual male patient with AIDS. Necrotizing stomatitis is a rapidly progressive ulcerative and necrotic infection that causes massive destruction of the oral tissues and underlying bone. Like hiv periodontitis, it appears to be related to the immune suppression caused by human immunodeficiency virus (hiv) infection; importantly, it may be life threatening. In this case, initial resolution resulted from local debridement in association with metronidazole therapy. Long-term clinical management consisted of monthly professional prophylaxis, good oral hygiene, and daily rinses with chlorhexidine. This case suggests that progressive oral necrotizing infection should be recognized as one element in the spectrum of oral manifestations of hiv infection.- - - - - - - - - - ranking = 1.2keywords = periodontitis (Clic here for more details about this article) |
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