1/8. Histopathology and electron and immunofluorescence microscopy of gingivitis granulomatosa associated with glossitis and cheilitis in a case of Anderson-fabry disease.A 17-year-old white boy with signs, symptoms, and family history of angiokeratoma corporis diffusum universale, Anderson-fabry disease (AFD), developed recurrent and then persistent swelling of both lips, erythematous hyperplastic gingivae, and a pebbled tongue. Positive blood findings were raised serum IgE, decreased T-cell level, and increased B-cell level. Histopathology of the gingiva showed noncaseating granulomas with multinucleate giant cells containing Schaumann bodies and large plasma-cell infiltrates in which immunofluorescence demonstrated immune globulins of several classes. Electron microscopy and histochemistry demonstrated ceramide in the vasculature. No glycolipid was found in the macrophages or giant cells of the granulomas which, in contrast, resembled sarcoid reactions. plasma cells with Russell bodies and immune reaction-induced degranulation of mast cells were also identified. The pathogenesis of the oral findings possibly relates to altered immune reactivity associated with damage to the microvasculature analogous to that in melkersson-rosenthal syndrome.- - - - - - - - - - ranking = 1keywords = gingiva (Clic here for more details about this article) |
2/8. Transient lingual papillitis: a papulokeratotic variant.Transient lingual papillitis is an inflammatory disease involving the fungiform papillae of the tongue and is typically localized, accompanied by pain or tenderness, and of short duration. The unusual clinical and pathologic findings regarding a condition we identify as a recurring papulokeratotic variant of transient lingual papillitis are described. In the child whose case we present, this condition was nonpainful and florid in distribution. The etiology, clinical features, and histopathology of this heretofore-undescribed variant are discussed and compared with the findings in previously reported cases of transient lingual papillitis.- - - - - - - - - - ranking = 0.96084038151534keywords = papilla (Clic here for more details about this article) |
3/8. Case report: the importance of oral manifestations in diagnosing iron deficiency in childhood.AIM: The aim of this article is to report a case of iron deficiency diagnosed in a child after routine oral examination. CASE REPORT: A 5-year-old male child of African descent was brought to the paediatric dental clinic of a public university in Rio de Janeiro, brazil. His mother's main complaint was her child's decayed teeth and sensitivity in the tongue every time he ate spicy or hot food. Anamnesis revealed chronic respiratory problems due to allergy, two previous episodes of anaemia and hospitalization about 15 months before the dental visit because of severe primary herpetic gingivostomatitis. Soft tissue examination revealed his tongue had various patches of atrophic mucosa characterizing absence of papillae in these areas. The child's dietary assessment indicated that he never ate meat or vegetables. Haematological investigation showed that the child probably had an iron deficiency, although the full blood count was not totally compatible with anaemia. A rapid initial recovery was quite noticeable after the beginning of oral therapy with ferrous sulphate, as remission of tongue sensitivity as well as papillae neoformation were observed.- - - - - - - - - - ranking = 1.9216807630307keywords = papilla (Clic here for more details about this article) |
4/8. Rhomboid glossitis in atypical location: case report and differential diagnosis.Median rhomboid glossitis (MRG) is an uncommon benign abnormality of the tongue, most frequently affecting men. It is typically located around the midline of the dorsum of the tongue, anterior to the lingual "V", appearing as a reddish, rhomboid area, depapillated, flat maculate or mamillated and raised by 2 - 5 mm. This paper reports a case of rhomboid glossitis in a 61-year-old man who consulted for a painless raised lesion on the dorsum of the tongue, in left paramedial (not medial) location. Histopathological findings were compatible with rhomboid glossitis. Other diagnoses considered but ruled out on the basis of the clinical and histopathological findings were haemangioma, pyogenic granuloma, amyloidosis, granular cell tumour, and squamous cell carcinoma. This case confirms that rhomboid glossitis may occur in paramedial locations.- - - - - - - - - - ranking = 0.96084038151534keywords = papilla (Clic here for more details about this article) |
5/8. Granulomatous gingivitis in Anderson-fabry disease.The patient is suffering from Anderson-fabry disease. This was documented by family history, clinical findings, histochemical and electronmicroscopic demonstration of ceramide in the blood vessels, and enzyme studies. The patient, at age 17, developed a unique gingival enlargement, gingivitis granulomatosa, a cobbled tongue, glossitis granulomatosa, and a lip enlargement, cheilitis granulomatosa. This was not found in other members of the family. The clinical, histological, and electronmicroscopic findings were analogous to melkersson-rosenthal syndrome. The patient did not have sarcoidosis or other specific granulomatous diseases. These were ruled out by skin examination, chest films, histology, and skin sensitivity testing, nor did he have Dilantin associated gingival enlargement. The patient had only taken the drug for a brief period at age 11 when he had a generalized granulomatous lymphadenopathy which was not categorized with certainty. This could have been secondary to Anderson-fabry disease aggravated by a minor infection, an idiosyncratic reaction to Dilantin, or the lymph node equivalent of the granulomatous response that later affected the gingiva. Although the gingival enlargement appeared to be a manifestation of an unusual syndrome, local therapy in the form of oral hygiene instruction, dental prophylaxis, gingivectomy, and regular maintenance therapy was successful in treatment and prevention of recurrence.- - - - - - - - - - ranking = 2keywords = gingiva (Clic here for more details about this article) |
6/8. A form of stomatitis induced by excessive peppermint consumption.This paper reports on a form of stomatitis and glossitis associated with extremely prominent circumvalate papillae in two patients who consumed excessive amounts of mint-flavoured sweets.- - - - - - - - - - ranking = 0.96084038151534keywords = papilla (Clic here for more details about this article) |
7/8. Two cases of recurrent herpetic infection of the tongue.Recently, a number of reports have been published on recurrent herpetic infection of the oral mucosa. In most of these cases, the infected tissue is the fixed intraoral mucosa, such as the gingiva or hard palate. infection of movable mucosa such as the tongue, which is reported in the present paper, has not been reported in detail previously. In each of the two cases reported in the present paper, intraoral lesions were diagnosed as recurrent herpes-glossitis after isolation of the herpes simplex virus (HSV).- - - - - - - - - - ranking = 0.5keywords = gingiva (Clic here for more details about this article) |
8/8. Eruptive familial lingual papillitis: a new entity?In order to describe the characteristic signs and course of a possibly new clinical entity, we undertook a clinical study of a series consisting of four families (5 children and 10 relatives) with a distinctive eruption of the tongue. The disease always started in a child, usually an infant (mean age 15.2 months), and then spread to one or several other members of the family. It had an abrupt onset and was characterized by difficulties in feeding, increased salivation, and irritability. Inflamed, hypertrophic fungiform papillae were seen on the tip and the dorsolateral part of the tongue, some having a pseudopustular appearance. There were no vesicles, erosions, signs of geographic tongue, or oral thrush; the central part of the tongue, the lips, gingivae, palate, and throat were normal. The acute phase lasted 6 to 7 days and was self-limited. A few days later, one or several relatives experienced an intense burning sensation on the tongue, with an increase and exacerbation caused by food intake, with the identical features of inflamed papillae. The duration of the stomatitis was usually 1 week for the infants, but longer for some adults. The similarity of these cases suggests the existence of a new clinical entity possibly of viral origin. We propose naming this eruption "eruptive familial lingual papillitis."- - - - - - - - - - ranking = 2.4216807630307keywords = papilla, gingiva (Clic here for more details about this article) |