1/28. Histopathology and electron and immunofluorescence microscopy of gingivitis granulomatosa associated with glossitis and cheilitis in a case of Anderson-fabry disease.A 17-year-old white boy with signs, symptoms, and family history of angiokeratoma corporis diffusum universale, Anderson-fabry disease (AFD), developed recurrent and then persistent swelling of both lips, erythematous hyperplastic gingivae, and a pebbled tongue. Positive blood findings were raised serum IgE, decreased T-cell level, and increased B-cell level. Histopathology of the gingiva showed noncaseating granulomas with multinucleate giant cells containing Schaumann bodies and large plasma-cell infiltrates in which immunofluorescence demonstrated immune globulins of several classes. Electron microscopy and histochemistry demonstrated ceramide in the vasculature. No glycolipid was found in the macrophages or giant cells of the granulomas which, in contrast, resembled sarcoid reactions. plasma cells with Russell bodies and immune reaction-induced degranulation of mast cells were also identified. The pathogenesis of the oral findings possibly relates to altered immune reactivity associated with damage to the microvasculature analogous to that in melkersson-rosenthal syndrome.- - - - - - - - - - ranking = 1keywords = tongue (Clic here for more details about this article) |
2/28. Chronic herpes simplex virus type I glossitis in an immunocompromised man.herpes simplex virus (HSV) type 1 (HSV-1) infection of the tongue commonly accompanies acute primary herpetic gingivostomatitis. However, recurrent infection of the tongue is exceptional and is restricted to immunocompromised individuals. A 57-year-old man with corticosteroid-dependent chronic obstructive pulmonary disease and sciatica presented with a chronic median glossitis due to HSV-1. The main clinical and histological feature was massive necrosis of the entire mucosa. immunohistochemistry demonstrated a considerable amount of HSV gB, gC and gD envelope glycoproteins dispersed in the chorion. In contrast, HSV-1 dna was detected only in a limited number of epithelial cells using in situ hybridization. The extent of necrosis and the pattern of viral dna and envelope protein distribution represent unique features of median herpetic glossitis, which are not found in more common types of HSV infection.- - - - - - - - - - ranking = 2keywords = tongue (Clic here for more details about this article) |
3/28. Serious complication of tongue piercing.The case of an 18-year-old patient who developed critical upper airway compromise after central tongue piercing is presented. Otolaryngologists must be aware of the many potential complications of tongue piercing and their management.- - - - - - - - - - ranking = 6keywords = tongue (Clic here for more details about this article) |
4/28. Painful tongue lesions associated with a food allergy.Transient lingual papillitis is an inflammatory disease of the tongue that can be very symptomatic in children. This case report describes the clinical features of transient lingual papillitis in a 7-year-old boy that was associated with a food allergy. The potential causes of this condition are reviewed and a differential diagnosis is provided.- - - - - - - - - - ranking = 5keywords = tongue (Clic here for more details about this article) |
5/28. taste disorder involving Hunter's glossitis following total gastrectomy.We treated five patients with Hunter's glossitis following total gastrectomy. The major complaints of the patients were taste disorder and abnormal glossal sensation. In all five cases, the patient's tongue was red and smooth, and laboratory testing showed the presence of macrocytic anemia and decreased serum concentration of vitamin B12 (cyanocobalamin). Gustometry was carried out in four cases and the results documented the presence of taste disorder. All five patients were treated by administration of vitamin B12, which led to improvements in the appearance of the tongue, the patients' subjective complaints and the results of taste testing. When patients present with a red, smooth tongue, Hunter's glossitis (which can easily be improved by administration of vitamin B12) should be considered in the differential diagnosis.- - - - - - - - - - ranking = 3keywords = tongue (Clic here for more details about this article) |
6/28. Recovery of anaerobic bacteria from a glossal abscess in an adolescent.Glossal abscess is infrequent in children. Anaerobic bacteria are rarely recovered from this infection and never have been reported in children or adolescents. A 15-year-old patient presented with a tongue abscess following trauma. Aspirate of the abscess yielded polymicrobial anaerobic flora: prevotella melaninogenica, fusobacterium nucleatum, and peptostreptococcus micros. The patient recovered following incision and drainage and 14 days of antimicrobial therapy with clindamycin. This report illustrates the recovery of anaerobic bacteria from glossal abscess in an adolescent.- - - - - - - - - - ranking = 1keywords = tongue (Clic here for more details about this article) |
7/28. Transient lingual papillitis: a papulokeratotic variant.Transient lingual papillitis is an inflammatory disease involving the fungiform papillae of the tongue and is typically localized, accompanied by pain or tenderness, and of short duration. The unusual clinical and pathologic findings regarding a condition we identify as a recurring papulokeratotic variant of transient lingual papillitis are described. In the child whose case we present, this condition was nonpainful and florid in distribution. The etiology, clinical features, and histopathology of this heretofore-undescribed variant are discussed and compared with the findings in previously reported cases of transient lingual papillitis.- - - - - - - - - - ranking = 1keywords = tongue (Clic here for more details about this article) |
8/28. Case report: the importance of oral manifestations in diagnosing iron deficiency in childhood.AIM: The aim of this article is to report a case of iron deficiency diagnosed in a child after routine oral examination. CASE REPORT: A 5-year-old male child of African descent was brought to the paediatric dental clinic of a public university in Rio de Janeiro, brazil. His mother's main complaint was her child's decayed teeth and sensitivity in the tongue every time he ate spicy or hot food. Anamnesis revealed chronic respiratory problems due to allergy, two previous episodes of anaemia and hospitalization about 15 months before the dental visit because of severe primary herpetic gingivostomatitis. Soft tissue examination revealed his tongue had various patches of atrophic mucosa characterizing absence of papillae in these areas. The child's dietary assessment indicated that he never ate meat or vegetables. Haematological investigation showed that the child probably had an iron deficiency, although the full blood count was not totally compatible with anaemia. A rapid initial recovery was quite noticeable after the beginning of oral therapy with ferrous sulphate, as remission of tongue sensitivity as well as papillae neoformation were observed.- - - - - - - - - - ranking = 3keywords = tongue (Clic here for more details about this article) |
9/28. Kaposi's sarcoma of the tongue associated with median rhomboid glossitis in a non-AIDS patient. A case report.Kaposi's sarcoma (KS) of the tongue is extremely rare in immunocompetent patients. We report a case of KS of the tongue associated with a median rhomboid glossitis. The main clinical, pathological and immunohistochemical features allowed the differential diagnosis.- - - - - - - - - - ranking = 6keywords = tongue (Clic here for more details about this article) |
10/28. Localized amyloid tumor of the tongue. A case report and review of the literature.Amyloid is usually deposited in the tongue, as a part of generalized amyloidosis. Isolated localized amyloidosis of the tongue is relatively rare. We report such a case which presented with glossodynia and glossopyrosis and was thought clinically to represent median rhomboid glossitis. Histologically the amyloid stained positively with congo-red giving green birefringence under polarized light, was not abolished after permanganate pretreatment and did not react immunohistochemically for amyloid A, beta 2 microglobulin and transthyretin.- - - - - - - - - - ranking = 6keywords = tongue (Clic here for more details about this article) |
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