1/30. Nosocomial pneumonia likely caused by stenotrophomonas maltophilia in two patients with polymyositis.We report two cases of polymyositis (PM) complicated with nosocomial pneumonia probably caused by stenotrophomonas maltophilia, which was resistant to multiple antimicrobials. In the first case, the chest CT findings and high serum endotoxin level as well as sputum culture results were helpful for the proper diagnosis and the therapy was successful. However the second patient died of a lung abscess in spite of the intensive antibiotic therapy. When PM patients develop pneumonia unresponsive to various antibiotics, a multi-drug-resistant bacteria such as stenotrophomonas maltophilia should be considered as the pathogen.- - - - - - - - - - ranking = 1keywords = nosocomial (Clic here for more details about this article) |
2/30. Primary pseudomonas meningitis in an adult, splenectomized, multitransfused thalassaemia major patient.A 19-year-old splenectomized, multitransfused female patient with beta-thalassaemia major developed primary meningitis due to P. putida. Her blood cultures were negative. P. putida is an unusual nosocomial organism to cause primary meningitis. Infection due to this organism carries high mortality. However, owing to early diagnosis and energetic treatment this patient survived without any sequelae. A review of serious infections over the last 7 years in patients in our thalassaemia care centre revealed 11 serious infections among our splenectomized patients (n = 46) and none in the non-splenectomized group (n = 106). Surprisingly, all overwhelming infections (23.8% in the splenectomized group) were caused by Gram-negative bacilli like klebsiella, pseudomonas, aeromonas and campylobacter species. As all our splenectomized patients had prior pneumococcal vaccination and oral penicillin prophylaxis, overwhelming septicaemia due to S. Pneumoniae was successfully prevented, but an increasing incidence of overwhelming sepsis due to Gram-negative bacilli, against which no vaccination or suitable prophylactic antibiotics are available, is now posing a new threat to this vulnerable group of patients.- - - - - - - - - - ranking = 1keywords = nosocomial (Clic here for more details about this article) |
3/30. stenotrophomonas maltophilia endocarditis of prosthetic aortic valve: report of a case and review of literature.stenotrophomonas maltophilia (previously known as xanthomonas maltophilia and pseudomonas maltophilia ) is an aerobic, nonfermenting, gram-negative bacillus, which has emerged as a serious nosocomial pathogen in patients with compromised immunity. It is a rare cause of endocarditis with only 20 cases previously reported in medical literature. The risk factors associated with S maltophilia endocarditis include intravenous drug abuse, dental treatment, previous cardiac surgery, and infected intravascular devices. S maltophilia is resistant to multiple antibiotics, which leads to frequent therapeutic failures. Although the optimal antibiotic treatment for S maltophilia endocarditis remains unknown, most of the patients received 2 or more antibiotics. We report a case of S maltophilia endocarditis of prosthetic aortic valve, associated with a painless aortic dissection, that responded well to a combination of ciprofloxacin and chloramphenicol. The literature is reviewed to elaborate the disease characteristics, the treatments used, and the prognosis of the S maltophilia endocarditis.- - - - - - - - - - ranking = 1keywords = nosocomial (Clic here for more details about this article) |
4/30. Acral necrosis by stenotrophomonas maltophilia.BACKGROUND: stenotrophomonas maltophilia (SM) has been considered a nosocomial pathogen. Nevertheless, community acquired infection may occur more frequently than usually recognized. CASE: We describe distal necrosis of the fingers by SM in a farmer, contracted in the community and successfully treated with a combination of cotrimoxazole and ciprofloxacin. The patient was diagnosed with chronic lymphocytic leukaemia 6 months later. CONCLUSIONS: This unusual presentation shows that infection with SM should be included in the differential diagnosis of the skin and soft tissue infection, even in apparently healthy patients.- - - - - - - - - - ranking = 1keywords = nosocomial (Clic here for more details about this article) |
5/30. Fulminant stenotrophomonas maltophilia soft tissue infection in immunocompromised patients: an outbreak transmitted via tap water.Soft tissue infection caused by stenotrophomonas maltophilia is uncommon, but nosocomial infections had been reported. We describe herein 2 young female patients, with severe neutropenia, on broad spectrum antimicrobial agents for neutropenic fever, with Hickman-type central venous catheter, who developed mucocutaneous and soft tissue infections with rapidly progressive and devastating course. Cultures from the skin of both patients and from blood of one of them grew S. maltophilia. Both patients died and post mortem examination of the patient with S. maltophilia bacteremia revealed extensive soft tissue necrosis and a vegetation on the mitral valve that grew S. maltophilia. The infection occurred in both patients at the same time and in the same ward. Epidemiological study was done, and surveillance cultures grew the organism from the faucets from the room of 1 patient and also from some of the neighboring rooms in our ward but not from any other ward nor in the water reservoir of the building.- - - - - - - - - - ranking = 33.974180244768keywords = nosocomial infection, nosocomial (Clic here for more details about this article) |
6/30. stenotrophomonas maltophilia meningitis, bacteremia and respiratory infection.stenotrophomonas maltophilia is an increasingly recognized cause of nosocomial infection of special interest because of its resistance to multiple antimicrobial agents. We report a case of generalized infection by S. maltophilia, including meningitis, bacteremia and respiratory tract infection, in a patient who had undergone multiple neurosurgical procedures and who was treated with trimethoprim-sulphamethoxazole.- - - - - - - - - - ranking = 33.974180244768keywords = nosocomial infection, nosocomial (Clic here for more details about this article) |
7/30. stenotrophomonas maltophilia endocarditis.stenotrophomonas maltophilia is a gram-negative bacillus that is increasingly associated with serious nosocomial infections, especially in immunocompromised patients; however, the occurrence of endocarditis due to this organism is rare. This report describes a case of S. maltophilia endocarditis associated with a central venous catheter. The literature on Stenotrophomonas endocarditis is reviewed. Given the high morbidity and mortality of these infections, early antibiotic therapy utilizing trimethoprim-sulfamethoxazole, along with a second agent and removal of prosthetic devices, is recommended.- - - - - - - - - - ranking = 33.974180244768keywords = nosocomial infection, nosocomial (Clic here for more details about this article) |
8/30. liver abscess caused by stenotrophomonas maltophilia: report of a case.We report the case of a melioidosis-like abscess of the liver caused by Stenotrophomonas (xanthomonas) maltophilia infection in a Chinese man living in hungary. Although this appears to be the first documentation of a liver abscess of this origin in a nonimmunocompromised patient, our case report demonstrates that this common facultative pathogen can also cause liver abscess and sepsis. After repeated negative blood cultures, histological examinations of liver biopsies suggested the possibility of chronic melioidosis, but the microbiological examination performed directly on the same specimen identified a stenotrophomonas maltophilia infection. Surgical drainage was performed and sulphamethoxazole/trimethoprim therapy was commenced, after which the patient recovered fully. The facultative pathogen S. maltophilia, which most often causes nosocomial infections, may cause severe sepsis and liver abscess. We wish to draw attention to the fact that the antibiotic sensitivity of S. maltophilia is not necessarily the same in vivo and in vitro. This can create difficulties in both diagnosis and treatment.- - - - - - - - - - ranking = 33.974180244768keywords = nosocomial infection, nosocomial (Clic here for more details about this article) |
9/30. Novel nosocomial infections by stenotrophomonas maltophilia: first reported case from Lucknow, North india.We describe a case of empyema with infected ascites caused by stenotrophomonas maltophilia, which has rarely been reported as pathogenic. The source was determined to a disinfectant solution. The isolate was sensitive to a newer carbapenem-meropenem, and the patient was treated successfully. This case represents a novel dual presentation of a nosocomial infection by the isolate in question.- - - - - - - - - - ranking = 169.87090122384keywords = nosocomial infection, nosocomial (Clic here for more details about this article) |
10/30. stenotrophomonas maltophilia: a serious and rare complication in patients suffering from burns.stenotrophomonas maltophilia is rarely implicated in clinical infections but it constitutes a significant nosocomial pathogen, especially in immunocompromised patients. This report describes the first case of a generalised infection caused by S. maltophilia that included bacteremia, wound and respiratory tract infection in a patient suffering from burns. Given the emergence of S. maltophilia nosocomial infections, especially in patients with burns, isolation of the bacterium from blood cultures should prompt the commencement of adequate antibiotic treatment.- - - - - - - - - - ranking = 34.974180244768keywords = nosocomial infection, nosocomial (Clic here for more details about this article) |
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