1/21. Granular cell tumors of the colon: report of a case and review of the literature.Granular cell tumors are uncommon, usually benign tumors that can be located anywhere in the body. They commonly occur in the oral cavity and in subcutaneous tissue. In the gastrointestinal tract, granular cell tumors are uncommon and are quite rare in the colon. To date, 55 patients diagnosed with granular cell tumors of the colon have been reported in the literature, only 15 had multiple tumors. We describe the case of a 38-year-old man with a family history of colon cancer who was diagnosed with multiple colonic granular cell tumors after a screening colonoscopy. This seems to be the first report of this type. However, in our patient, the diagnosis of colonic granular cell tumors was incidental and there is no data that correlates adenomas or colorectal cancer with granular cell tumors of the colon. Finally, since granular cell tumors are usually benign, we suggest a conservative approach to patients with multiple granular cell tumors of the colon by means of endoscopic resection and a strict endoscopic follow-up.- - - - - - - - - - ranking = 1keywords = oral cavity, cavity (Clic here for more details about this article) |
2/21. granular cell tumor in a child's finger.granular cell tumor is an uncommon tumor found in the hand. It is probably of Schwann cell origin and may be associated with a peripheral nerve. Although it is often described as a painless tumor of the oral cavity and skin, its presentation in the fingers or hand is often painful--a characteristic not well recognized.- - - - - - - - - - ranking = 1keywords = oral cavity, cavity (Clic here for more details about this article) |
3/21. granular cell tumor of the common bile duct: a case report.Granular cell tumors (GCTs) are uncommon soft tissue tumors, usually presenting in the skin and subcutaneous tissue tongue and oral cavity. We present a case report of granular cell tumor of the common bile duct involving both extra- and intrapancreatic portions. The histogenesis appears to be related to schwann cells, similar to granular cell tumors of other sites, as evidenced by histologic and immunohistochemical findings. review of the English literature concerning biliary tract GCTs revealed a high occurrence in African-American females in their third decade. By-pass operation to correct the biliary tract obstruction may be appropriate, if the nature of the tumor can be obtained from intraoperative diagnosis by frozen section.- - - - - - - - - - ranking = 1keywords = oral cavity, cavity (Clic here for more details about this article) |
4/21. granular cell tumor at the hepatic duct confluence mimicking Klatskin tumor. A report of two cases and a review of the literature.BACKGROUND: Granular cell tumors are rare tumors most often located in the oral cavity, skin or subcutaneous tissue. The occurrence of this tumor in the biliary tree is extremely rare. methods: Two patients are described presenting with biliary obstruction due to a tumor at the hepatic duct confluence. One patient is a 38-year-old white male with concomitant cutaneous granular cell tumors, and the other a 50-year-old white female. RESULTS: Hilar excision was performed in both patients. Histopathology of the tumors revealed a proliferation of cells with granular cytoplasm, diagnosed as granular cell tumor. CONCLUSION: At preoperative examination, hilar granular cell tumors are difficult to differentiate from cholangiocarcinoma, sclerosing cholangitis or more common benign biliary tumors. Treatment consists of surgical excision after which prognosis is favorable.- - - - - - - - - - ranking = 1keywords = oral cavity, cavity (Clic here for more details about this article) |
5/21. Congenital epulis.Epulis is a rare tumor of the newborn, also known as granular cell tumor of the newborn or Neumann's tumor. This tumor arises from the mucosa of the gingiva, most commonly from the anterior part of the maxillary alveolar ridge, and is typically seen as a mass protruding out of the newborn child's mouth, which may interfere with respiration or feeding. Epulis is seen only in the newborn and is a different entity from other granular cell tumors. The tumor has a marked female preponderance of 8:1. The recommended treatment is prompt surgical resection. Recurrences of the tumor and damage to future dentition have not been reported, suggesting that radical excision is not warranted. A newborn female with such a mass is described. The tumor was resected using a carbon dioxide laser; the postoperative course was uneventful. On histologic examination, it was composed of diffuse sheets and clusters of polygonal cells containing small round to oval nuclei and abundant coarsely granular cytoplasm. The tumor cells stained positive for vimentin, and negative for S100-protein, actin, desmin, laminin, keratin, estrogen, and progesterone receptors. Electron microscopic examination showed granular cells containing heterogeneous electron-dense granules, lysosomes, and cytoplasmic lipid droplets. The clinical and microscopic features of such tumors are reviewed.- - - - - - - - - - ranking = 0.014625505591513keywords = mouth (Clic here for more details about this article) |
6/21. Abrikossoff's tumor.Abrikossoff's tumor is a disease that more commonly affects the oral cavity but can also occur at other sites. It develops between the second and sixth decades of life, more frequently among women and blacks. The neoplasm can affect all parts of the body. The head and neck areas are affected in 45% to 65% of cases and of these, 70% are located interorally (tongue, oral mucosa, hard palate). The benign form shows polygonal cells with granular, eosinophilic cytoplasm and small nuclei. The malignant form, however, is associated with a high mitotic index and pleomorphic cellular tissue. The clinical aspect of the neoformation is a swelling covered by mucus of normal appearance. Studies of the neoformation show that in addition to the objective examination, further instrumental research is necessary, i.e., with nuclear magnetic resonance or computed tomography with contrast CT scan. However, the only examination that can confirm the clinical diagnosis is the histological examination. The only treatment for Abrikossoff tumor is surgery. The surgical treatment provides for an extirpation of the neoformation with the overhanging mucus and the underlying periosteum. In this work, the authors discuss a case of Abrikossoff tumor affecting the mucus of the right side of the hemipalate in a 53-year-old patient and present a review of the literature.- - - - - - - - - - ranking = 1keywords = oral cavity, cavity (Clic here for more details about this article) |
7/21. Congenital granular cell tumors localized to the arm.We report an instance of congenital granular cell tumors localized to the arm of a female infant. While granular cell tumors are well described during infancy as congenital epulis of the oral cavity, this case is unusual in both its location and histologic characteristics. The lesions, located around the antecubital fossa, were comprised of CD34-positive, S-100-negative granular cells. In addition, there were numerous eccrine glands in the upper dermis. The salient features of the case are discussed and reviewed in the context of the literature pertaining to this unusual entity.- - - - - - - - - - ranking = 1keywords = oral cavity, cavity (Clic here for more details about this article) |
8/21. granular cell tumor treated with Mohs micrographic surgery: report of a case and review of the literature.BACKGROUND: Granular cell tumors are uncommon soft tissue neoplasms of neural origin that most often arise in the oral cavity. Penile lesions are distinctly uncommon. Mohs micrographic surgery (MMS) is a highly effective treatment for several cutaneous neoplasms when tissue conservation is crucial. OBJECTIVE: To examine the use of MMS for this soft tissue malignancy. methods: We report only the eighth granular cell tumor of the penis. The literature was reviewed regarding the use of MMS for these neoplasms. RESULTS: MMS was performed to minimize the destruction of normal tissue in treating this patient's granular cell tumor. Only one previous article documented the use of MMS for this soft tissue tumor. CONCLUSION: Although utilized infrequently to treat granular cell tumors, MMS may prove beneficial when lesion location or size render tissue conservation or assuredness of cure paramount.- - - - - - - - - - ranking = 1keywords = oral cavity, cavity (Clic here for more details about this article) |
9/21. Eagle syndrome produced by a granular cell tumor.Eagle syndrome includes elicitation of pain on swallowing, turning the head, or extending the tongue. The syndrome is thought to be caused by irritation of the glossopharyngeal nerve, most commonly caused by its impingement against an elongated styloid process. We present a rare case of a granular cell tumor presenting as Eagle syndrome. Granular cell tumors orignate from schwann cells and are most common in the subcutaneous tissue of the head, neck, and oral cavity, especially the tongue. A granular cell tumor is typically benign and solitary, rarely malignant. The differential diagnosis, diagnostic algorithm, and treatment are presented.- - - - - - - - - - ranking = 1keywords = oral cavity, cavity (Clic here for more details about this article) |
10/21. Congenital epulis of the newborn: a case report.This paper describes the case of a day old baby who was admitted to hospital because of the presence of a large intraoral swelling that was preventing her from breast feeding. Clinical examination showed a firm, pedunculated, lobulated nodule protruding from the mouth and attached to the maxillary alveolus to the left of the midline. The mucosa was normal in appearance. The growth was excised under local anaesthesia and showed a histological appearance consistent with a congenital epulis of the newborn. Healing was complete and no recurrence was seen at review after two weeks. Conservative treatment of congenital epulis is often sufficient but in this case, the nodule prevented feeding. Excision was incomplete but, as in other cases treated in the same way, there has been no obvious tendency to recur.- - - - - - - - - - ranking = 0.014625505591513keywords = mouth (Clic here for more details about this article) |
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