Cases reported "Granuloma, Foreign-Body"

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1/31. Severe migratory granulomatous reactions to silicone gel in 3 patients.

    In humans implanted with silicone gel breast prostheses, a mild foreign body response results in the formation of a collagenous capsule around the prosthesis. Although many such patients may show evidence of a microscopic granulomatous foreign body reaction upon examination of capsular material at explantation of a prosthesis, it is unusual to have large, palpable granulomas, even in the presence of rupture or leakage. Rare patients have had severe local inflammation and complications resulting from silicone migration to the axilla, arm, or abdominal wall. We describe 3 patients who had deforming granulomas after implant rupture, along with other consequences of silicone gel migrating down the upper extremity. Silicone gel, once it leaves the implant, is not biologically inert and in some persons can elicit profound pathologic responses.
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ranking = 1
keywords = breast
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2/31. Are triglyceride breast implants really biocompatible?

    A case of augmentation mammaplasty with triglyceride implants is presented. Histological examination of the capsules 3 years postimplantation showed retained, irregular, refractile yellow-brown fragments embedded in granulomatous tissue.
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ranking = 4
keywords = breast
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3/31. Expanding silicone granuloma.

    Complications of breast augmentation using silicone implants have been the subject of much discussion. We report a single case of a silicone granuloma, which has exhibited unusual behaviour in that it has grown rapidly and significantly. Whilst silicone granulomata have been reported on many occasions in the past, to our knowledge this is the first report of a rapidly growing example.
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ranking = 1
keywords = breast
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4/31. Two cases of cholesterol granuloma of the breast.

    We report two cases of cholesterol granuloma of the breast clinically diagnosed as malignant and describe the features. The first patient was a 74-year-old woman who complained of a lump in the left breast. The mammography and ultrasonography suggested a malignant mass. Fine needle aspiration showed multinucleated giant cells. We suspected breast cancer, but cholesterol granuloma was diagnosed on excisional biopsy. The second case was a 51-year-old woman who was found to have a breast tumor on a screening mammography. The mammography and ultrasonography suggested carcinoma, but excisional biopsy revealed cholesterol granuloma. Reports of cholesterol granuloma of the breast are very rare. cholesterol granuloma should be considered in the differential diagnosis of breast carcinoma.
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ranking = 10
keywords = breast
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5/31. Foreign body granulomas of the breast presenting as bilateral spiculated masses.

    In asia, mammography following the injection of foreign materials into the breasts for cosmetic augmentation is frequently seen and diagnosis based on the typical radiologic findings is straightforward. We report the unusual radiologic findings in two patients with foreign body granulomas caused by injected foreign materials and discovered incidentally during screening work up. The mammographic findings were bilateral, hyperdense, spiculated masses, with occasional microcalcification, and at sonography, markedly hypoechoic, spiculated solid masses, located near the pectoralis muscle and partly extending into it, were observed. These radiologic findings mimicked malignancy.
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ranking = 5
keywords = breast
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6/31. Silicone migration from silicone-injected breasts: magnetic resonance images.

    Injection of liquid silicone into the breast was performed illicitly in the 1950s to 1960s and was subsequently prohibited. Many complications arise from silicone injection, and liquid silicone migration is a complication that has not been widely reported. The authors present magnetic resonance images of a patient with liquid silicone migration from the breast to the upper chest and lower neck. Breast ultrasonographic and mammographic findings are also presented for correlation.
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ranking = 6
keywords = breast
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7/31. rupture of a silicone gel mammary prosthesis and amyloidosis: a case report.

    There has been a great deal of controversy regarding the safety of silicone breast implants. Silicone gel prostheses older than 10 years have the risk of either leakage or outright rupture. The role of silicone gel in relation to connective tissue disease or amyloidosis has not been proved by current serologic, immunologic, or epidemiologic tests. In this paper, we present a case with renal amyloidosis and a history of untreated silicone implant rupture for five years.
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ranking = 1
keywords = breast
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8/31. Local recurrence of breast cancer around a prosthesis dome.

    We report a patient who, 2 years after mastectomy and breast reconstruction using a permanent expander, developed metastatic carcinoma around the filling port of the prosthesis. We believe this is the first description of such a condition, the differential diagnosis of which includes a silicone granuloma.
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ranking = 5
keywords = breast
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9/31. Paraffinoma in anterior abdominal wall mimicking liposarcoma.

    Paraffinoma of breast is a recognized complication of paraffin injection for breast augmentation. Liquid paraffin can extend along fascial planes to involve adjacent tissues. A rare case of paraffinoma in anterior abdominal wall, which was misdiagnosed as a soft tissue liposarcoma before surgical excision, is reported. It was heterogeneous with marked posterior acoustic shadowing and small peripheral cysts on ultrasound. On MRI, it had ill-defined margins and was heterogeneous in signal intensity. Small round components which were hypointense on all sequences were demonstrated. There is significant overlapping of imaging features between paraffinoma and soft tissue liposarcoma. Histological differentiation from well-differentiated liposarcoma may also be difficult. A detailed clinical history of previous paraffin injection for breast augmentation is very important for correct interpretation of imaging and histopathological findings.
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ranking = 3
keywords = breast
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10/31. Paraffinoma of the knee.

    We present the case of a 90-year-old man with a swollen, painful knee and a history of paraffin injections. radiography showed soft tissue streaky and nodular calcifications without erosions. MR imaging showed globular areas of low signal intensity on T1- and T2-weighted images which became even more hypointense on STIR sequences, and an infiltrative hypointense region containing areas of high signal on T1-weighted, T2-weighted and STIR images. biopsy confirmed soft tissue foreign body granulomata, fibrous reaction and areas of inflammation. We believe this to be the first report of MR imaging of paraffinoma outside the breast.
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ranking = 1
keywords = breast
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