1/10. granuloma annulare of the eyelid: a case report and review of the literature.granuloma annulare is a benign, relatively common dermatosis of childhood. Lesions typically occur on the extremities and resolve spontaneously over a period of several months to years. Localized facial involvement is rare. We report a case of granuloma annulare confined to the left eyelid. The literature on periocular granuloma annulare is reviewed. This diagnosis should be considered for any acquired papules of the periorbital area, especially if there is a history of antecedent trauma. Unnecessary surgical excision can then be avoided.- - - - - - - - - - ranking = 1keywords = dermatosis (Clic here for more details about this article) |
2/10. uveitis associated with granuloma annulare.PURPOSE: To report a case of uveitis associated with granuloma annulare (GA). GA is a benign, usually self-limited dermatosis of unknown origin, causing necrobiotic dermal and subcutaneous papules. So far, ocular involvement has not been reported in GA. methods: We describe a case of uveitis with GA. Ocular examination findings were consistent with uveitis. Histopathologic studies on lower extremity lesions revealed features consistent with GA. RESULTS: The patient was successfully treated with systemic and topical corticosteroids. After two months, however, the skin and eye lesions relapsed. When the same treatment was restarted, her lesions regressed within four weeks. CONCLUSIONS: This case provides an example of concomitant uveitis and GA. To our knowledge, this is the first report of this combination.- - - - - - - - - - ranking = 1keywords = dermatosis (Clic here for more details about this article) |
3/10. Disseminated granuloma annulare as a presentation of acquired immunodeficiency syndrome (AIDS).Localized granuloma annulare is the commonest form of a granulomatous dermatosis characterized by flesh coloured or violaceous papules often arranged in rings. Several rare atypical variants are also reported including disseminated or generalized, subcutaneous and perforating types. There is a predilection for females and a documented association with diabetes mellitus in some cases. Recently it has been suggested that atypical variants of granuloma annulare might be associated with the acquired immunodeficiency syndrome (AIDS). We describe a patient presenting with extensive generalized granuloma annulare in whom an underlying diagnosis of Human Immunodeficiency Virus (hiv) disease was confirmed.- - - - - - - - - - ranking = 1keywords = dermatosis (Clic here for more details about this article) |
4/10. Isomorphic response after saphenectomy in a patient with granuloma annulare.Physical trauma has been reported as an etiologic factor of granuloma annulare, resembling a Koebner phenomenon. Moreover, granuloma annulare frequently arises at the same location of a previously healed, unrelated skin disease, mainly herpetic infection. These data seem to suggest that granuloma annulare might be a peculiar pattern of skin reaction to different stimuli, either physical or biologic, in predisposed subjects. In the case reported herein, the onset of a typical lesion of granuloma annulare at the site of saphenectomy might be explained as the result of an aberrant wound healing process, with release, by keratinocytes and/or langerhans cells, of lymphocyte-derived chemotactic cytokines, capable of promoting the development of the granulomatous lesion.- - - - - - - - - - ranking = 1.1662004704276keywords = skin disease (Clic here for more details about this article) |
5/10. granuloma annulare presenting as multiple nodules on the pinna.granuloma annulare is a benign, idiopathic, inflammatory dermatosis characterized clinically by dermal papules and annular plaques. We describe the case of a 40-year-old man who presented with a long history of multiple nodules on the left pinna. Histological examination revealed the typical necrobiotic granulomas of granuloma annulare. The condition predominantly affects the extremities of children and young adults; cases involving the pinna are extremely rare. Nodular lesions are common in otolaryngological practice, and this case illustrates the need for careful clinical assessment and appropriate biopsy in diagnosing lesions of the outer ear- - - - - - - - - - ranking = 1keywords = dermatosis (Clic here for more details about this article) |
6/10. Bilateral and subcutaneous palmar nodules in a 2-year-old child suggesting deep granuloma annulare.granuloma annulare is a benign, relatively common dermatosis in childhood. The subcutaneous form is rare, and lesions typically occur on the legs, buttocks and scalp. We report a case of a deep granuloma annulare confined to the palms of the hands in a 2-year-old child.- - - - - - - - - - ranking = 1keywords = dermatosis (Clic here for more details about this article) |
7/10. Congenital subcutaneous granuloma annulare.granuloma annulare is a palisading granulomatous skin disease which may be generalized, localized, perforating, or subcutaneous. Subcutaneous granuloma annulare is self-limiting, affecting infants and children, with typical postnatal onset. Here we report a patient with congenital clinical manifestations.- - - - - - - - - - ranking = 1.1662004704276keywords = skin disease (Clic here for more details about this article) |
8/10. Treatment of granuloma annulare with the 585 nm pulsed dye laser.BACKGROUND: granuloma annulare is a chronic asymptomatic dermatosis that is typically manifested by annular papules arising on the dorsa of the hands, feet, elbows, and knees. Multiple treatment modalities have been used with variable efficacy, but no known cure exists. Obtaining long-term resolution of involved areas is often a therapeutic challenge. OBJECTIVE: We report the results of treatment of a patient with localized erythematous granuloma annulare with a 585 nm flashlamp-pumped pulsed dye laser. methods: A single granuloma annulare plaque present on the left wrist for 3 years was treated on three occasions with a 585 nm flashlamp-pumped pulsed dye laser initially and repeated at months 5 and 13. RESULTS: After initial pulsed dye laser treatment, significant flattening and reduction of erythema were evident within the treated area. After a second treatment at month 5 and a third treatment at month 13, further improvement was evident, and long-term remission was achieved. CONCLUSION: Localized granuloma annulare may be difficult to manage, presenting a therapeutic challenge. Thorough understanding of available treatment options, their relative efficacies, and risks of complication can facilitate successful management of this chronic disease. Pulsed dye laser therapy may be an effective and relatively safe treatment option for erythematous granuloma annulare, although prospective studies in additional patients would be desirable. Improvement of the condition in a single patient does not imply that others might improve, and variability in response is more likely.- - - - - - - - - - ranking = 1keywords = dermatosis (Clic here for more details about this article) |
9/10. Annular elastolytic giant cell granuloma in an infant: improvement after treatment with oral tranilast and topical pimecrolimus.Annular elastolytic giant cell granuloma (AEGCG) is a rare granulomatous skin disease of unknown origin that is characterized clinically by annular patches with erythematous borders and hypopigmented centers and histologically by loss of elastic fibers and elastophagocytosis. We report a case of AEGCG in an 8-month-old boy that was successfully treated with oral tranilast and topical pimecrolimus (Elidel 1.0% cream).- - - - - - - - - - ranking = 1.1662004704276keywords = skin disease (Clic here for more details about this article) |
10/10. granuloma annulare associated with malignancy.granuloma annulare is a benign dermatosis. Although granuloma annulare usually occurs as an idiopathic condition, it has been described in oncology patients. I report the case of a man in whom the appearance and resolution of granuloma annulare occurred in a paraneoplastic manner. The diagnosis of his previously unsuspected pulmonary adenocarcinoma was preceded by the concurrent onset of granuloma annulare lesions and tumor-related systemic symptoms. Two other patients with malignancy-associated granuloma annulare are discussed: a woman with breast cancer and a woman with cervical cancer. In these cases, the appearance of granuloma annulare was also temporally associated with the detection of a previously undiagnosed malignancy or the discovery of recurrent metastatic disease. The resolution of the dermatosis was temporally associated with the successful treatment of the neoplasm in these individuals. granuloma annulare should be added to the list of cutaneous paraneoplastic syndromes that may occur in patients with solid tumors.- - - - - - - - - - ranking = 2keywords = dermatosis (Clic here for more details about this article) |
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