Cases reported "Hand-Foot Syndrome"

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1/3. Spontaneous rupture of adrenal pheochromocytoma with capsular invasion.

    A 67-year-old Japanese man developed a sudden onset of severe right-side upper abdominal pain, nausea and vomiting. On hospitalization, physical examination revealed sweating, tachycardia, hypertension and the appearance of peripheral vasoconstriction. An urgent computed tomography scan with contrast demonstrated a large hematoma in the right retroperitoneal space. A phentolamine test and an 131iodine metaiodobenzylguanidine scan suggested pheochromocytoma. An elective right adrenalectomy was successfully performed after pretreatment for sufficient volume replacement with continuous administration of alpha- and beta-adrenergic blocking agents. Pathological diagnosis was an adrenal pheochromocytoma 9.0 x 6.5 cm in diameter with evidence of capsular invasion, which could be associated with a tear in the capsule.
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2/3. Rare cause of abdominal pain in childhood: computed tomography findings in a 14-year-old boy with a colonic carcinoma.

    Carcinoma of the colon during infancy and childhood is a rare disease, and the diagnosis is usually not taken into consideration in a child complaining of abdominal pain. Owing to the lack of awareness of its occurrence and the histological cell type, it generally presents as advanced disease. We report on the case of a 14-year-old patient admitted to hospital with an acute abdomen and a 2-month history of night sweats and weight loss of 10 kg. Ultrasound and computed tomography revealed an unclear mass of the lower abdomen, and colonoscopic histopathologic examination disclosed an obstructing tubular-papillary adenocarcinoma of the sigmoid colon. Colonic carcinoma should be included as a differential diagnosis in young patients with abdominal pain of unknown etiology.
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3/3. Spontaneous rupture of the spleen in initial presentation of Hodgkin's disease.

    A 46-year-old man presented with a four-week history of fevers, occasional chills, and a two-week history of sweats and poor appetite. He also complained of progressive weakness and lethargy. After initial evaluation, while awaiting further consultation, the patient developed rapidly progressing abdominal pain and light-headedness. He was moved immediately into the emergency treatment area. He was noted to have an acute abdomen and was taken to surgery. An enlarged Hodgkin's-infiltrated spleen with an actively bleeding hematoma was removed. The patient denied any history of trauma.
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