1/4. A case of giant cholesteatoma extending to the posterior fossa.We present a 43-year-old male patient who developed a giant cholesteatoma with lateral sinus obliteration and involvement of the posterior cranial fossa. The only complaints were left-sided aural discharges and total sensorineural hearing loss. Examination revealed a mass lesion consistent with cholesteatoma within the left middle ear. Computed tomography and magnetic resonance imaging showed an extensive acquired cholesteatoma in the left middle ear, invading the posterior cranial fossa and leading to lateral sinus obliteration. The patient underwent left radical mastoidectomy. He had an uneventful postoperative follow-up for 13 months. This case emphasizes the value of preoperative radiologic assessment of giant cholesteatomas that may present with relatively few or limited symptoms.- - - - - - - - - - ranking = 1keywords = giant (Clic here for more details about this article) |
2/4. giant cell arteritis with CD8 instead of CD4 T lymphocytes as the predominant infiltrating cells in a young woman.giant cell arteritis is rarely reported in people aged less than 50 years. We report a case of giant cell arteritis in a woman who developed symptoms of dizziness, headache, bilateral sensorineural hearing impairment, and had 1 episode of transient left hemiparesis before the age of 30. Carotid angiography showed multiple segmental narrowing in cranial vessels. Subsequently, at the age of 31, she had weight loss and developed a fever. Chest radiograph revealed mediastinal widening, and chest computed tomography revealed dilated pulmonary arteries and veins. coronary angiography and aortography showed irregular narrowing of the descending aorta and multiple stenosis, with aneurysmal dilatation involving the proximal and distal coronary, pulmonary and mesenteric arteries. Multinucleated giant cells and predominant CD8 T lymphocyte infiltration were noted in a left temporal artery biopsy specimen. The patient's age and the finding of dilated pulmonary veins and prominent CD8 T lymphocytes in the biopsy specimen suggest that this case was a distinct form of systemic giant cell arteritis.- - - - - - - - - - ranking = 0.5keywords = giant (Clic here for more details about this article) |
3/4. Giant cranial extradural primary fibroxanthoma: a case report.Primary fibroxanthoma of the cranium is an extremely rare condition. Xanthomatous tumors of the central nervous system are occasionally associated with diseases such as hand-Schuler-Christian disease, malignant fibrous histiocytoma, hyperlipidemia, and a complication of metabolic or storage disorders. However, until 2003, only a few cases of primary fibroxanthoma have been reported. We report a giant fibroxanthoma destroying the lateral skull base unaccompanied by a systemic or metabolic disease.- - - - - - - - - - ranking = 0.16666666666667keywords = giant (Clic here for more details about this article) |
4/4. stapes anomaly and cochlear sensory cell changes. A scanning electron microscope study.This paper reports the pathological findings in the cochleae of a 66-year-old man examined under a scanning electron microscope (SEM). Columella-shaped stapes, which were the only anomalous changes in the middle ear cleft, were found in both ears. Beside this, giant hair formation and fusion of stereocilia in the inner sensory cells were also observed in the apical part of the lower basal turn. Since the patient had no history of ototoxic drug use or other ear disease episodes, it is suggested that these inner hair cell changes might have been caused by the conductive disorder accompanying the stapes anomaly. Giant hair formation was discussed from the inner ear findings of 14 other cases examined by a SEM.- - - - - - - - - - ranking = 0.16666666666667keywords = giant (Clic here for more details about this article) |