1/2. hearing loss as a sequel of lumbar puncture.Only a few case reports have been published about hearing impairment following lumbar puncture, and not all were thoroughly documented by audiograms. We present nine cases of hearing loss following myelography, lumbar puncture, and spinal anesthesia. We speculate that this rare complication arises only in persons with a wholly or partially patent cochlear aqueduct, and occurs via the release of perilymphatic fluid in the cerebrospinal space. hearing loss was seen in eight of the nine patients in the lower frequencies, and in six of the nine patients on both sides. Recovery to normal hearing was noticed in six of the nine patients. Transient hearing loss may occur more often than it is generally assumed, and the symptom can remain unnoticed. Since not all of these hearing losses proved to be fully reversible, we suggest informing patients about this complication for medicolegal reasons.- - - - - - - - - - ranking = 1keywords = puncture (Clic here for more details about this article) |
2/2. hearing loss after discontinuing secondary prophylaxis for cryptococcal meningitis: relapse or immune reconstitution?Relapse and immune reconstitution syndrome are difficult to distinguish in hiv-infected patients treated with antiretroviral therapy (art). We report on a 26-year-old hiv-infected male (CDC C3) with hearing loss on the right side 2 months after discontinuing secondary prophylaxis for cryptococcal meningitis. CD4 cell counts had increased from 32/microl to stable counts > 200/microl for the preceding 6 months on art but hiv replication was not fully suppressed (7,000 copies/ml). magnetic resonance imaging identified lesions at the origin of the right cranial nerve VIII. Lumbar puncture revealed monocytic pleocytosis, slightly increased protein, but normal glucose and lactate levels, negative microbiological studies. fluconazole was restarted and a new art regimen was started in order to fully suppress hiv replication. Clinical and radiological signs were reversible during follow-up, and secondary prophylaxis was stopped after 6 months without adverse events. We review 26 published cases of cryptococcal infections with immune reconstitution syndrome and highlight the distinguishing features.- - - - - - - - - - ranking = 0.16666666666667keywords = puncture (Clic here for more details about this article) |