1/305. Squamous cell metastasis from the tongue to the myocardium presenting as pericardial effusion.Cardiac metastasis from head and neck cancer is rarely encountered. We present a base-of-tongue squamous cell carcinoma with metastasis to the heart that was diagnosed antemortem. autopsy series indicate that tongue cancer may metastasize more frequently to the heart than from other head and neck sites. However, none of these studies was controlled. Most importantly, cardiac metastasis should be suspected in any patient with cancer in whom new cardiac symptoms develop. The diagnosis is best confirmed with two-dimensional echocardiography or cardiac MRI. A myocardial or endocardial biopsy specimen can be obtained with angiographic guidance. Despite the improvement in diagnostic capability, available treatments are only palliative. All patients eventually die of their metastatic disease.- - - - - - - - - - ranking = 1keywords = cancer (Clic here for more details about this article) |
2/305. cardiac tamponade originating from primary gastric signet ring cell carcinoma.A 45-year-old man with dry cough and dyspnea was referred by a medical practitioner for evaluation of heart failure on February 10, 1996. Chest X-ray revealed increased cardiothoracic ratio, and ultrasonographic echocardiography disclosed massive pericardial effusion with right ventricular collapse. cardiac tamponade was diagnosed and pericardiocentesis was performed. Ten days after admission, the pleural effusion had become more pronounced, and thoracocentesis was performed. carcinoembryonic antigen level was elevated in both the pericardial and pleural effusion, and cytology implicated adenocarcinoma, which suggested malignant effusion. Endoscopic study disclosed gastric cancer in the posterior wall of the upper body, and the histopathological diagnosis was signet-ring cell carcinoma. The patient died of respiratory failure on May 2, 1996, and autopsy was performed. The final diagnosis was gastric cancer with pulmonary lymphangitis, pericarditis, and pleuritis carcinomatosa, accompanied by enlargement of mediastinal and paraaortic lymph nodes. Interestingly, the primary signet-ring cell carcinoma of the stomach was situated mostly in the mucosa. Deep in the submucosal region, there was prominent invasion of the intralymphatic vessels, without direct destruction of the mucosa muscularis.- - - - - - - - - - ranking = 0.66666666666667keywords = cancer (Clic here for more details about this article) |
3/305. Anitschkow cells in the human heart.A case of multiple myeloma, who died of congestive heart failure of unknown cause, is presented. Microscopically, Anitschkow cells with caterpillar and owl-eyed nuclei were scattered in the interstitium of the myocardium. To know the pathological significance of their appearance, histological observations of normal, developing and autoimmune disease-bearing heart specimens were made. A few Anitschkow cells were commonly seen in the interstitium of the adult heart with or without autoimmunity, and fetal cardiomyocytes often showed Anitschkow-type nuclear configurations. Moreover, squamous cancer cells metastatic to the myocardium exhibited Anitschkow-type nuclei. No Anitschkow-type nuclei were observed in extracardiac locations. In conclusion, formation of Anitschkow-type nuclear features in the human heart is not necessarily specific to the autoimmune status, but can be regarded as being ubiquitously provoked by the continuous contraction of heart muscle cells.- - - - - - - - - - ranking = 0.33333333333333keywords = cancer (Clic here for more details about this article) |
4/305. Minimally invasive extirpation of a left-ventricular myxoma.As myxomas usually are benign neoplasms a minimally invasive technique would be an interesting alternative for their extirpation because the surgical trauma is reduced. In one male patient with a diagnosed left-ventricular myxoma minimally invasive surgery was carried out using the Port-Access method. 2D echocardiography, EBT, and MRI were performed preoperatively to obtain exact information about topography, calcifications, and malignity. Minimally invasive extirpation was successful and the mitral valve could be preserved. Histopathological examination revealed a cardiac myxoma extirpated in toto. At one-year follow-up there was no recurrence of the tumor.- - - - - - - - - - ranking = 1.0261052399279keywords = neoplasm (Clic here for more details about this article) |
5/305. Cardiac angiosarcoma: early diagnosis. A case report.Malignant tumours are rare and their diagnostic verification is more frequent at a post-mortem examination. We present a clinical case of a angiosarcoma of the atrium dextrum in a patient where the diagnosis was done precociously. The clinical case we are describing presents some characteristics not noted in literature. The patient did not present any other clinical signs other than giving assumption of the presence of neoplasm and/or secondary localization. The transthoracic echographic exam revealed the methodology to enable the removal of the neoplasm, the outline of which, was better defined with the transesophageal probe.- - - - - - - - - - ranking = 2.0522104798558keywords = neoplasm (Clic here for more details about this article) |
6/305. Both atrial resection and superior vena cava replacement in sleeve pneumonectomy for advanced lung cancer.Extended sleeve pneumonectomy including removal of the superior vena cava, right atrium and parts of left atrium on cardiopulmonary bypass was successfully performed in a 40-year-old man. The tumour was histologically proven a T4 N1 stage with margins free from tumour. Adjuvant radiochemotherapy was administered postoperatively on an outpatient base. The patient did well for 7 months then he died from myocardial infarction due to metastatic infiltration of the right coronary artery. Other metastatic deposits were not found at autopsy. More data from extended pulmonary resections are required to demonstrate a benefit.- - - - - - - - - - ranking = 1.3333333333333keywords = cancer (Clic here for more details about this article) |
7/305. Cardiac autotransplant for surgical treatment of a malignant neoplasm.Because of their anatomic location, cardiac sarcomas often interfere with cardiac function. Excision is considered to palliate the cardiac defect, but complete excision is often difficult owing to access, particularly in left atrial tumors. Incomplete resection results in tumor recurrence. To achieve complete resection of a large left atrial sarcoma, we used the technique of cardiac explantation, extracorporeal resection of the tumor with cardiac reconstruction, and cardiac autotransplantation.- - - - - - - - - - ranking = 4.1044209597115keywords = neoplasm (Clic here for more details about this article) |
8/305. Primary pericardial synovial sarcoma with detection of the chimeric transcript SYT-SSX.We report a case of a 19-year-old woman with a primary pericardial synovial sarcoma that extended from the right ventricular free wall to the posterior aspect of the left anterior thoracic wall. Synovial sarcoma was diagnosed by the detection of the chimeric transcript SYT-SSX using reverse transcriptase-polymerase chain reaction (RT-PCR). This transcript is generated by reciprocal translocation between chromosomes X and 18, and is specific to synovial sarcoma that usually occurs in the extremities of young adults. When pathological and immunohistochemical diagnosis of synovial sarcoma is difficult, the molecular biological technique using RT-PCR becomes a powerful method of confirmation of this neoplasm.- - - - - - - - - - ranking = 1.0261052399279keywords = neoplasm (Clic here for more details about this article) |
9/305. osteosarcoma metastatic to the kidneys without lung involvement.Symptomatic renal metastasis is very rare in osteosarcoma. A few reported cases had pulmonary metastases before renal involvement. We present a case of metastatic renal osteosarcoma without pulmonary involvement. The patient presented with hematuria 8 years after initial treatment of osteosarcoma of the left distal femur. Computed tomography revealed a bilateral calcified renal mass. The patient died of disease 4 months after detection of the metastases. At autopsy, metastatic osteosarcoma was discovered in the bilateral kidney, both renal veins, inferior vena cava and right atrium. There was no pulmonary involvement. We emphasize the need for renal evaluation for the follow-up of patients with osteosarcoma.- - - - - - - - - - ranking = 0.12171725520919keywords = kidney (Clic here for more details about this article) |
10/305. Successful one-stage resection of intravenous leiomyomatosis of the uterus with extension into the heart.Intravenous leiomyomatosis of the uterus is a rare neoplasm characterized by nodular masses of benign smooth muscles with intraluminal growth to the inferior vena cava and, in some cases, to the heart. It may cause abdominal and cardiovascular symptoms and is a serious risk of death when it reaches the tricuspid valve. Surgery is the best treatment and must be applied as soon as possible using cardiopulmonary bypass. The authors report a new case that had cardiac involvement and was successfully resected. The symptoms, imaging diagnosis, pathological and histopathological findings, tumors that mismatched the intravenous leiomyomatosis (IVL), and the use of circulatory arrest and deep hypothermia are discussed. A review of the literature is included.- - - - - - - - - - ranking = 1.0261052399279keywords = neoplasm (Clic here for more details about this article) |
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