1/52. Recurrent proptotic diplopia due to congestive expansion of cavernous haemangioma with relapsing right-sided cardiac failure.A 75-year-old man with a recent history of pulmonary embolism, presented with collapse followed by a gran mal seizure and right-sided non-pulsatile proptosis. On recovery, he had diplopia on lateral and upward gaze and signs of congestive cardiac failure. Further pulmonary embolism was proven by lung scintigraphy. Computed tomography of his orbits confirmed a contrast-enhancing space-occupying lesion of the medial wall of the right orbit, with no intracranial abnormality. The patient was investigated for metastatic tumour as a possible cause of the space-occupying lesion and the unprovoked thromboembolic event, but no evidence of malignancy was found. The orbital lesion was not biopsied because of the risk of bleeding from anticoagulation. Three weeks later, the patient represented with recurrent cardiac failure, proptosis, and diplopia. A transorbital ultrasound confirmed an encapsulated, well-defined vascular lesion, with typical appearances and Doppler flow characteristics of a cavernous haemangioma. Diuretic therapy abolished the proptosis and diplopia in tandem with relief of the cardiac failure. This is the first description of recurrent proptosis with diplopia due to recurrent congestive expansion of an orbital cavernous haemangioma.- - - - - - - - - - ranking = 1keywords = coagulation (Clic here for more details about this article) |
2/52. Surgery combined with copper wire implantation in the management of cavernous orofacial haemangiomas.This paper describes the management of a case of an extensive orofacial haemangioma by surgery combined with copper wire implantation. This technique of copper wire implantation in the management of orofacial haemangiomas was carried out for the first time in jamaica by the authors. The use of percutaneous copper needles to induce therapeutic coagulation in cavernous haemangiomas, however, is not new, and this has been the basis of the use of copper wire.- - - - - - - - - - ranking = 1keywords = coagulation (Clic here for more details about this article) |
3/52. Intratumoral consumption of indium-111-labeled platelets in a child with splenic hemangioma and thrombocytopenia.The authors report kasabach-merritt syndrome (KMS) in a patient with thrombocytopenia and splenic hemangioma. A 13-month-old boy with a history of anemia, thrombocytopenia, and abdominal mass was admitted to the hospital. The scintigraphic studies showed that a large mass contiguous to the spleen was responsible for the platelet uptake. After partial splenectomy, the platelet count returned to normal. This report of KMS in a child with splenic hemangioma suggests that the scintigraphic studies are mandatory to confirm diagnosis. indium-111-labeled platelets are useful in identifying hemangiomatous sequestration of platelets in patients with thrombocytopenia.- - - - - - - - - - ranking = 72.660398780355keywords = consumption (Clic here for more details about this article) |
4/52. Giant hepatic hemangioma with kasabach-merritt syndrome: is the appropriate treatment enucleation or liver transplantation?We present a case of giant cavernous hemangioma of the liver with disseminated intravascular coagulopathy (kasabach-merritt syndrome) which was cured by enucleation. The 51 year old woman presented with increased abdominal girth and easy bruisability. Workup elsewhere revealed a massive hepatic hemangioma and she was started on radiation therapy to the lesion and offered an orthotopic liver transplant. After careful preoperative preparation, we felt that resection was possible and she underwent a successful enucleation. The operation and postoperative course were complicated by bleeding but she recovered and remains well in followup after 6 months. All coagulation parameters have returned to normal. Enucleation should be considered the treatment of choice for hepatic hemangiomas, including those presenting with kasabach-merritt syndrome. The benefits of enucleation as compared to liver transplantation for these lesions are discussed.- - - - - - - - - - ranking = 46.775492574923keywords = coagulopathy, intravascular, coagulation (Clic here for more details about this article) |
5/52. Surgical treatment of a cavernous hemangioma of the left atrial roof.A hemangioma that occurs as a primary tumor of the heart is extremely rare. The authors experienced a cavernous hemangioma located in the epicardium of the left atrial roof in a patient who had paroxysmal atrial fibrillation. Resection of the tumor and cryo-coagulation yielded a satisfactory clinical course. No recurrence of the tumor is noted at the time of 5 years after operation.- - - - - - - - - - ranking = 1keywords = coagulation (Clic here for more details about this article) |
6/52. Cavernous hemangioma of the retina: report of four cases.Four patients had cavernous hemangiomas of the retina. The lesions, which usually occur in asymptomatic individuals, are unusual hamartomas comprised of saccular aneurysms containing venous blood and located on the surface of the retina or at the optic nervehead. Two patients had photocoagulation to destroy the lesions. In one patient, the lesion was totally destroyed after treatment to it and to the surrounding retina; in the second patient, a portion of the lesion had enlarged greatly when examined 5 years after photocoagulation. The hemangiomas of the other 2 patients have been observed without therapeutic intervention--the course we prefer for the majority of cases.- - - - - - - - - - ranking = 2keywords = coagulation (Clic here for more details about this article) |
7/52. Giant cavernous haemangioma with kasabach-merritt syndrome: a case report and review.We report the case of a 4-month-old boy presenting with a giant cutaneous haemangioma complicated by kasabach-merritt syndrome (KMS) with severe thrombocytopenia. After poor response to corticosteroid therapy and subsequent treatment with interferon alpha-2a, radiotherapy led to tumour regression and resolution of the disseminated intravascular coagulopathy over a 14-month period of follow up. Whereas the various available treatment options are reviewed and discussed in this article, the therapy of choice should be chosen individually. CONCLUSION: to date prospective randomised and controlled trials are required to investigate the optimal management of patients with kasabach-merritt syndrome.- - - - - - - - - - ranking = 45.775492574923keywords = coagulopathy, intravascular (Clic here for more details about this article) |
8/52. Living donor liver transplantation for giant hepatic hemangioma with kasabach-merritt syndrome with a posterior segment graft.We present a case of a giant hepatic hemangioma with kasabach-merritt syndrome, which was cured by living donor liver transplantation. A 48-year-old woman complained of abdominal fullness and appetite loss. The laboratory data showed disseminated intravascular coagulation and a morphologic evaluation revealed a giant hepatic hemangioma involving both lobes of the liver. Living donor liver transplantation was indicated for kasabach-merritt syndrome and an unresectable liver tumor. A posterior segment graft was used because the remnant liver volume of the donor might have been too small to sustain the liver function of the donor. The postoperative course was uneventful, and the recipient was discharged from hospital on day 15 after the transplantation without complications.- - - - - - - - - - ranking = 8.8119642219372keywords = intravascular coagulation, intravascular, coagulation (Clic here for more details about this article) |
9/52. Coexistence of cystic intra-abdominal lymphangiomas and diffuse venous haemangiomas in adult life.Diffuse haemangioma and intra-abdominal lymphangioma are rare in adults. In this case report, we present a 33-year-old female with coexisting multiple cutaneous and visceral cavernous haemangiomas and two huge intra-abdominal lymphangiomas of 25 and 35 cm in diameter. The organs involved were the liver, pericardium, renal hilus and bladder. She died due to disseminated intravascular coagulation and multiorgan failure, which resembled kasabach-merritt syndrome. The coexistence of generalised haemangiomas and intra-abdominal lymphangiomas and the lack of complaints until the age of 33 years makes her an unusual case in the literature. We also emphasise the other clinical conditions that should be considered in the differential diagnosis.- - - - - - - - - - ranking = 8.8119642219372keywords = intravascular coagulation, intravascular, coagulation (Clic here for more details about this article) |
10/52. Blue rubber bleb nevus syndrome: immunohistochemical study.Blue rubber bleb nevus is a rare entity consisting of distinctive angiomas in the skin and gastrointestinal tract, leading to occult or profound gastrointestinal bleeding and chronic anemia. The efficacy has been documented of systemic treatment with corticoids, interferon, vincristine, and, more recently, subcutaneous octreotide in the presence of active lesion proliferation or disseminated intravascular coagulation. A case of blue rubber bleb nevus syndrome with oral hemangiomas in a 24-year-old woman is reported. The surgical specimens were subjected to immunohistochemical study, which showed all of the hemangiomas to be in an inactive phase.- - - - - - - - - - ranking = 8.8119642219372keywords = intravascular coagulation, intravascular, coagulation (Clic here for more details about this article) |
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