1/5. angiolymphoid hyperplasia with eosinophilia: a classic clinical presentation with histologic features of angiosarcoma.BACKGROUND: angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare disease manifested by the proliferation of morphologically distinct endothelial cells. OBJECTIVE: To illustrate by a case report the clinical and varied histopathologic findings of ALHE. methods: A 29-year-old woman presented with a clinical picture of ALHE but had several histologic features of angiosarcoma. RESULTS: Management of this patient included repeat biopsies of the lesions, excision of the involved areas, careful histologic examination of the entire specimen, and appropriate follow-up. CONCLUSION: ALHE may present with various histologic features. knowledge of the spectrum of benign and malignant vascular neoplasms helps manage these challenging cases.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |
2/5. Spontaneous rupture of a right atrial angiosarcoma and cardiac tamponade.Primary cardiac angiosarcoma is a rare disease of difficult diagnosis and poor prognosis frequently associated with recurring hemopericardium. We report the case of a 30-year-old female with a right atrial angiosarcoma and spontaneous rupture to the pericardial cavity, who was diagnosed during an emergency exploratory thoracotomy, whose indication was cardiac tamponade. This is the 8th case reported in the literature. Clinical findings are discussed and a literature review is provided.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |
3/5. tuberous sclerosis: unusual associations in four cases.tuberous sclerosis is a rare disease with classic primary or secondary changes affecting mainly the cerebrum, skin, kidneys, and heart. Such lesions are generally hamartomatous and thus display malignant features only in rare cases. This paper describes four cases of tuberous sclerosis which were unique in their association with certain unusual congenital, metabolic, and tumorous conditions.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |
4/5. Primary angiosarcoma of the heart. Report of a case and review of the literature.We report on a 44-year-old male with primary cardiac angiosarcoma who died 11 months after onset of nonspecific symptoms (thoracic pain and general fatigue) of intracerebral metastases. A right atrial tumor mass and a pericardial effusion could be demonstrated by transthoracic and transesophageal echocardiography. Cardiac angiography showed a right atrial hemangioma, fed by the right coronary artery. In a review of 108 cases of primary cardiac angiosarcoma we summarize clinical features, diagnostic means, therapeutic approaches and life expectancy of this rare disease.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |
5/5. Spontaneous rupture of splenic angiosarcoma: a case report of chemotherapeutic approach and review of the literature.Angiosarcoma of the spleen is a rare disease, and the prognosis of this disease is extremely unfavorable. We herein review the case of a 45-year-old Japanese woman, who received a combined chemotherapy with cyclophosphamide, Adriamycin, vincristine, and prednisone after splenectomy and experienced a good response. The various types of chemotherapy for this disease are also discussed with references to the above case because no effective chemotherapeutic protocol for angiosarcomas has yet to be established.- - - - - - - - - - ranking = 1keywords = rare disease (Clic here for more details about this article) |