Cases reported "Hyaline Membrane Disease"

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1/38. The decline and early fall of neonatal pulmonary hemorrhage.

    Seven years' experience (1965-1972) with neonatal pulmonary hemorrhage at the University of colorado was reviewed. Pulmonary hemorrhage still occurs frequently as a preterminal event in hyaline membrane disease. As an isolated "pure" entity, however, pulmonary hemorrhage has shown a marked decline. This phenomenon is probably related to advances in neonatal intensive care. The radiographic pattern of "pure" pulmonary hemorrhage in the newborn is most commonly a diffuse alveolar infiltrate. Since pure hemorrhage is now an uncommon entity, the radiologist can reasonably suggest this diagnosis on rare occasions only, in the clinical setting of profound hypoxia.
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2/38. Pulmonary venous air embolism in hyaline membrane disease.

    A newborn infant with the respiratory distress syndrome in whom pulmonary venous air embolism (PVAE) developed as a complication of positive pressure therapy is reported. The underlying pathophysiology in this disorder is probably the development of alveolar-capillary fistulae secondary to unduly high intrabronchial pressures. An increased awareness by radiologists and clinicians of PVAE as a potential complication of aggressive respiratory therapy will result in more frequent recognition of this uncommon but lethal disorder.
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3/38. hyaline membrane disease in a term neonate.

    hyaline membrane disease is primarily a disorder of preterm infants. Its occurrence in term infants is very uncommon and therefore may escape attention. We describe a term infant who developed severe respiratory distress soon after birth. diagnosis of hyaline membrane disease was revealed at autopsy.
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4/38. Surfactant replacement therapy in newborns with hyaline membrane disease.

    This article discusses the use of surfactant replacement therapy in the management of neonates with hyaline membrane disease (HMD). Included is an overview of HMD, current treatment modalities, a case presentation, nursing implications for managing the infant with HMD, and a nursing care plan. Administration of surfactant is discussed, along with implications for nursing research.
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5/38. diagnostic imaging of hyaline membrane disease.

    The case of a premature infant with hyaline membrane disease (respiratory distress syndrome) is discussed. On chest X-ray reduced volume and transparency of both lungs with ground-glass appearance and presence of bilateral air bronchogram was visualized. These findings are analyzed with respect to possible diagnostic alternatives.
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6/38. air embolism and pulmonary interstitial emphysema in a preterm infant with hyaline membrane disease.

    A preterm infant with severe hyaline membrane disease requiring extreme mechanical ventilation developed pulmonary air leaks with consecutive shock. The chest roentgenogram showed bilateral pulmonary interstitial emphysema and gas within the heart silhouette as well as in the hepatic veins, inferior v. cava, portal vein, and many abdominal vessels. The respiratory and circulatory failure by massive systemic gas embolism resulted in death.
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7/38. High frequency oscillatory ventilation in neonates with respiratory distress.

    High frequency oscillatory ventilation (HFOV) was attempted in ten infants with severe respiratory failure not responding to conventional ventilation (CV); it was, therefore, used as a rescue measure. HFOV was successful in improving the respiratory status of seven infants, all with hyaline membrane disease (HMD). Five of these infants survived, of the remaining two, one died of massive peri/intra-ventricular haemorrhage and the other of cholestasis associated with total parenteral nutrition. It was unsuccessful in three infants, one with meconium aspiration, the second died within two hours commencing HFOV and the third with severe depression and hypotonia.
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8/38. cytomegalovirus endolabyrinthitis.

    A premature male infant, who died 22 days after birth with hyaline membrane disease, was found to have had cytomegalic inclusion disease at autopsy. Histopathologic examination of the temporal bones showed cytomegalovirus (CMV) infection of the entire endolabyrinth without involvement of the neural and sensory structures. These findings support the thesis that late gestational or perinatal fetal CMV infection results in an endolymphatic labyrinthitis. We hypothesize that blood-borne virus passes from the stria vascularis into the endolymphatic spaces and infects the nonneurosensory epithelium. This pattern of infection differs from the perilabyrinthitis of human varicellazoster and experimentally produced mouse CMV.
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9/38. Fatal ureaplasmal pneumonia and sepsis in a newborn infant.

    ureaplasma urealyticum was isolated in pure culture from blood tracheal aspirate and lung tissue in a newborn infant, who died of a severe pneumonia within 48 h after birth. The clinical course was characterized by persistent pulmonary hypertension of the newborn (PPHN). Post-mortem examination revealed extensive hyaline membrane formation combined with signs of inflammation in both lungs. The clinical and histopathological picture resembled that of early onset group B haemolytic streptococcal pneumonia/sepsis.
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10/38. Systemic air embolism: a complication of ventilator therapy in hyaline membrane disease.

    Systemic air embolism in infants with hyaline membrane disease on positive pressure ventilation is a serious and frequently fatal complication. It is essential for both the paediatrician and radiologist to be aware of this disease entity. The incidence is increasing because of improved survival of very low birth weight infants and more aggressive therapy. We report two examples of systemic air embolism in infants.
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