Cases reported "Hyperostosis"

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1/15. Stress-induced SAPHO syndrome.

    We describe the case of a woman with the classic combination of features of synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) syndrome, including pustulosis palmo-plantaris and anterior chest wall involvement. The varying symptomology, etiology and pathogenesis of this syndrome and the contribution of stress are discussed. The authors ascribe the dearth of reported cases to lack of awareness and recognition of SAPHO, and not to the real incidence of the syndrome.
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ranking = 1
keywords = osteitis
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2/15. A case report of synovitis, acne, pustulosis, hyperostosis and osteitis syndrome presenting with spondylodiscitis.

    SAPHO syndrome stands for synovitis, acne, pustulosis, hyperostosis and osteitis. The common site of skeletal lesions in this syndrome is the sternocostoclavicular area. Spondylodiscitis is rarely described in published studies. In general, skin lesions develop before the onset of skeletal lesions. We report a case of SAPHO syndrome in which spondylodiscitis developed more than 1 year before the onset of pustulosis.
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ranking = 5
keywords = osteitis
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3/15. Basithoracic pain as first manifestation of pustulotic arthro-osteitis.

    We report the case of a woman with atypical anterior basithoracic pain as only initial symptom of pustulotic arthro-osteitis. early diagnosis was made only after development inferior lumbar pain, some months later. At that time, the radiological investigations revealed the osteoarticular counterpart of pustulotic arthro-osteitis.
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ranking = 6
keywords = osteitis
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4/15. Spinal hyperostosis--a rare skeletal manifestation of psoriasis vulgaris.

    A 28-year-old woman with uncomplicated psoriasis vulgaris presented with spinal hyperostosis and osteitis. The absence of peripheral arthritis, sacroiliitis, and diffuse idiopathic skeletal hyperostosis (DISH) raised the possibility that the spinal lesion was an extracutaneous manifestation of psoriasis. We review the association between uncomplicated psoriasis vulgaris and skeletal involvement.
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ranking = 1
keywords = osteitis
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5/15. Noninfectious osteitis: part of the SAPHO syndrome.

    SAPHO, a rare syndrome, is a recently suggested acronym for synovitis, acne, pustulosis, hyperostosis and osteitis. It encompasses many features which have been described in different but overlapping conditions. Not all of the syndrome components need to be present for inclusion in SAPHO to be justified, especially the dermatologic components. Two cases are described as examples. Clinicians should be aware of this rare disorder if positive early diagnoses are to be made in patients presenting with skeletal pain.
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ranking = 5
keywords = osteitis
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6/15. hyperostosis and multifocal osteitis: a purely rheumatological subset of the SAPHO syndrome.

    SAPHO has recently been proposed as an acronym to identify a syndrome characterized by synovitis, acne, pustulosis, hyperostosis and osteomyelitis. Several authors have, however, found that this rare condition may even occur without cutaneous manifestations. The work reported here presents the case of a 43-year-old male with skeletal involvement alone. An in-depth study of the patient revealed the arthro-osteitic pattern typical of the SAPHO syndrome. In agreement with previous reports, these data confirm that the present clinical picture of hyperostosis and osteitis, even without cutaneous involvement, is nonetheless related to the SAPHO syndrome.
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ranking = 5
keywords = osteitis
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7/15. Is diffuse sclerosing osteomyelitis of the mandible part of the synovitis, acne, pustulosis, hyperostosis, osteitis (SAPHO) syndrome? Analysis of seven cases.

    Diffuse sclerosing osteomyelitis of the mandible has been described as a localized disease of unknown origin. We offer evidence that mandibular involvement in the recently described synovitis acne pustulosis hyperostosis osteitis syndrome exactly fits the accepted description for diffuse sclerosing osteomyelitis of the mandible. The clinical, radiologic, and pathologic findings in seven such cases are presented and discussed.
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ranking = 5
keywords = osteitis
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8/15. Pustulotic arthro-osteitis: a cause of atypical chest pain and a new arthritic syndrome.

    We have described a 38-year-old white American woman who had a 7-year history of pain in the left anterior chest, neck, right wrist, and buttocks. The pain fluctuated in severity and appeared to coincide with worsening of her skin condition, palmoplantar pustulosis (PPP). She manifested the typical skeletal features of an arthritic condition referred to as pustulotic arthro-osteitis, which is frequently associated with the characteristic rash of PPP. This is an infrequently described disorder in the united states, possibly reflecting lack of familiarity or confusion with related disorders.
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ranking = 5
keywords = osteitis
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9/15. An aseptic inflammation of the clavicle in a patient with Crohn's disease. A potential manifestation of the SAPHO syndrome.

    A female patient with Crohn's disease developed an septic osteoarticular involvement of the left clavicle and sterno- and acromioclavicular regions. Repeated surgical revisions combined with a broad-spectrum antimicrobial treatment could not prevent the progress of the disease. However, the patient started to improve after the diagnosis of the SAPHO (synovitis, acne, pustulosis, hyperostosis and osteomyelitis) syndrome was made and the dose of her immunosuppressive therapy increased. This patient reminds of the existence of extraintestinal aseptic infections in association with inflammatory bowel disease (IBD). Moreover, it may provide further evidence on the significant association between SAPHO and IBD.
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ranking = 0.0021592640339463
keywords = inflammation
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10/15. Subpontic hyperostosis.

    Two cases of subpontic hyperostosis are presented. This condition is an intraoral bony exostosis that has been observed beneath a fixed partial denture. Subpontic hyperostosis seems to be associated exclusively with the posterior mandible, usually the first molar position. The first case occurred in a 64-yr-old Asian male and the second appeared bilaterally in a 79-yr-old female. It has not been described extensively in the literature, with only 33 cases having been reported previously. The etiology of this condition is unknown, with factors such as genetic predisposition, mechanical stress, and inflammation suggested as possible causes. Treatment of this hyperostosis is be surgical excision, and if necessary is usually due to the impingement of the growth on the pontic and the inability of the patient to maintain adequate oral hygiene in the area.
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ranking = 0.00053981600848658
keywords = inflammation
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