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1/4. latex and chickpea (cicer arietinum) allergy: first description of a new association.

    In this paper we describe the existence of cross-reactivity between allergens from latex and chickpea, a food from the Leguminosae family, which is common in the Mediterranean diet. We present the case report of a spina bifida boy with a clinical relevant food allergy to chickpea (oral syndrome dysphonia), developing after the appearance of latex allergy symptoms (lip angioedema intraoperative anaphylaxis). Specific IgE to latex and chickpea was demonstrated by skin prick tests, measurement of patient's serum specific IgE and IgE-immunoblotting. Cross-reactivity was studied by means of EAST-inhibition and western blotting-inhibition. A strong inhibition was observed in several IgE-binding bands when latex extract was used in solid phase and patient serum was preincubated with chickpea extract (chickpea extract as inhibitor phase). As far as we know, this is the first report of cross-reactivity between latex and chickpea, a food which should therefore be added to the extensive list of latex cross-reactive foods.
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ranking = 1
keywords = gum
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2/4. angioedema induced by inhalation of vapours from cooked white bean in a child.

    BACKGROUND: There are few references of allergic reaction to beans in childhood. We report the case of a seven years old boy who suffered from angioedema associated to inhalation of vapours from cooked white bean. methods: skin prick tests (SPT) were performed by prick-by-prick with cooked white bean and legumes. It was also determined total IgE and specific IgE antibodies to bean and legumes with the use of the CAP enzymo-immunoassay. Subsequently, a oral challenge test was carried out with white bean. RESULTS: The prick-by-prick with white bean was positive in our case, and negative in ten controls patients. Specific IgE in patient serum, assayed by CAP was positive for white bean and green bean. The patient developed angioedema after ingestion cooked white bean. CONCLUSION: we demonstrated a type I hypersensitivity to white bean in a seven years old child by SPT, specific IgE antibodies and challenge test.
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ranking = 2
keywords = gum
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3/4. Occupational asthma caused by guar gum.

    Some vegetable gums have been reported to cause asthma. We describe three subjects who were exposed at work to guar gum, which is derived from the outer part of Cyanopsis tetragonolobus, a vegetable that grows in india. The first subject worked for a pharmaceutical company; the second and third subjects worked at a carpet-manufacturing plant. All three subjects developed symptoms of rhinitis and asthma after the onset of exposure to guar gum. All subjects were atopic and demonstrated mild bronchial hyperresponsiveness to inhaled histamine at the time they were observed. skin prick tests demonstrated an immediate skin reaction to guar gum. All three subjects had high levels of serum IgE antibodies to guar gum. Specific inhalation challenges in which the three subjects were exposed for short intervals (less than or equal to 4 minutes) to powder of guar gum elicited isolated immediate bronchospastic reactions in two subjects and a dual reaction in the other subject.
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ranking = 10
keywords = gum
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4/4. Tissue hypersensitivity to dental materials.

    Five cases of tissue hypersensitivity to Scutan and two to Impregum are reported. The reaction to Scutan was a burning sensation in the mucosa in contact with the material, followed by swelling and erythematous ulcers producing heavy discomfort. All symptoms gradually disappeared after removal of the material. To Impregum the reaction was basically the same, only less vigorous since contact with the material is of limited duration. All the cases were women in the menopause. attention is drawn to the possibility of hormonal imbalance being a factor of importance in the development of hypersensitivity reactions to materials of this sort.
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ranking = 2
keywords = gum
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