1/11. linear iga bullous dermatosis in a patient with chronic renal failure: response to intravenous immunoglobulin therapy.linear iga bullous dermatosis is a blistering disease with a heterogeneous clinical manifestation, characterized by deposition of IgA along the basement membrane zone of perilesional skin on direct immunofluorescence. We describe a patient with chronic renal failure who experienced linear iga bullous dermatosis. Long-term administration of intravenous immunoglobulin therapy was associated with clinical remission lasting more than 12 months.- - - - - - - - - - ranking = 1keywords = dermatosis (Clic here for more details about this article) |
2/11. A case report: persistent acantholytic dermatosis in chronic renal failure.INTRODUCTION: This is the second case of persistent acantholytic dermatosis in a patient with chronic renal failure, seen at the same institution in 2 years. CLINICAL PICTURE: A 70-year-old Chinese man with end-stage renal failure on continuous ambulatory peritoneal dialysis for 6 months presented with pruritic rashes over the scalp and chest for 3 months. Histologically, the lesions resembled Darier's disease. Differential diagnoses include Darier's disease, Grover's disease and perforating dermatosis in chronic renal failure. TREATMENT: The patient was treated with anti-histamines, topical steroids and emollients. OUTCOME: Resolution of pruritus was documented. However, the extensive hyperkeratotic papules remained persistent. CONCLUSION: A chronic non-remitting course is to be expected for this dermatoses in which the aetiology is unknown.- - - - - - - - - - ranking = 1keywords = dermatosis (Clic here for more details about this article) |
3/11. ESRD-associated cutaneous manifestations in a hemodialysis population.Cutaneous manifestations occurring in patients with end stage renal disease (ESRD) can indicate systemic problems that have significant morbidity and mortality risks. skin changes are sometimes a consequence of the disease that caused the renal failure or may be an ESRD manifestation. pruritus is the most prevalent ESRD cutaneous complaint, but its pathogenesis is not understood. The pathophysiology, presentation, and nursing implications of perforating dermatosis, metastatic calcification, polytetraflouroethylene graft infection, and lichen planus are discussed with corresponding case reports.- - - - - - - - - - ranking = 0.16666666666667keywords = dermatosis (Clic here for more details about this article) |
4/11. Treatment of acquired perforating dermatosis with narrowband ultraviolet B.Acquired perforating dermatosis is difficult to treat. We describe effective therapy of acquired perforating dermatosis with narrowband UVB in 5 patients. phototherapy was given 2 or 3 times weekly. The dose was started at 400 mJ/cm(2) and increased to a maximum of 1500 mJ/cm(2). All lesions disappeared completely after 10 to 15 exposures without adverse effects. Two patients with diabetes mellitus but without chronic renal failure experienced no recurrence until 5 and 10 months after stopping the phototherapy. One patient undergoing hemodialysis for chronic renal failure experienced a recurrence of pruritus and small papules after 1 month. Two patients undergoing hemodialysis showed no recurrence during narrowband UVB maintenance therapy until 7 and 8 months.- - - - - - - - - - ranking = 1keywords = dermatosis (Clic here for more details about this article) |
5/11. Hemodialysis-related porphyria cutanea tarda--treatment failure with charcoal hemoperfusion.A 56-yr-old man presented with a photosensitive bullous dermatosis 1 yr after commencing hemodialysis. Urinary porphyrin levels were normal and fecal porphyrin levels only minimally increased, but the plasma uroporphyrin concentration was markedly elevated, being higher than that normally occurring in porphyria cutanea tarda. The high plasma uroporphyrin level was thought to result from the combined effects of increased porphyrin production and failure of adequate clearance by hemodialysis. Chronic alcohol ingestion, methyldopa therapy and elevated iron and aluminum levels may have contributed to the porphyrin overproduction. charcoal hemoperfusion proved unhelpful in lowering the plasma uroporphyrin concentration.- - - - - - - - - - ranking = 0.16666666666667keywords = dermatosis (Clic here for more details about this article) |
6/11. porphyria cutanea tarda and chronic renal failure.Bullous dermatosis developed in a patient with renal failure who was on hemodialysis. The results of standard tests for porphyria cutanea tarda--quantitation of urinary and fecal porphyrins by fluorometric assay--were within normal limits or were nondiagnostic. Assay of plasma using high-pressure liquid chromatography, however, revealed that this patient had a porphyrin profile consistent with porphyria cutanea tarda. A porphyria-like bullous eruption may occur in patients with chronic renal failure; however, in only a few cases have laboratory studies confirmed the diagnosis of porphyria cutanea tarda. Our experience suggests that, in patients with renal failure, a plasma assay may be more reliable than tests of the urine and feces in establishing a diagnosis in those patients who actually have disorders of porphyrin metabolism. We also report the results of assay of erythrocyte uroporphyrinogen decarboxylase activity and fecal isocoproporphyrin.- - - - - - - - - - ranking = 0.16666666666667keywords = dermatosis (Clic here for more details about this article) |
7/11. porphyria cutanea tarda in a haemodialysed patient.A bullous dermatosis, that arose about 2 years after the beginning of haemodialysis treatment, was due to a geniune hereditary porphyria cutanea tarda (PCT). The plasma porphyrins were extraordinarily high. Neither the residual renal function nor the haemodialysis--using different techniques and different materials--succeeded in reducing the plasma porphyrin levels to that usually found in PCT. The serious and rapid evolution of the cutaneous lesions towards a scleroderma-like state might have been due to this level of plasma porphyrins and to their passage into the tissues. The clearance of porphyrins is compared with that of 162 subjects affected by PCT. The porphyrin content in the plasma of seventy-five non-porphyric subjects undergoing maintenance dialysis was also studied.- - - - - - - - - - ranking = 0.16666666666667keywords = dermatosis (Clic here for more details about this article) |
8/11. porphyria cutanea tarda in a chronic hemodialysis patient.We have described a patient undergoing long-term hemodialysis who had bullae on the dorsum of the hands, extensor surfaces of the forearms, and the forehead. While clinically indistinguishable from earlier reports of bullous dermatosis of chronic renal failure, laboratory investigation documented prophyria cutanea tarda in this patient.- - - - - - - - - - ranking = 0.16666666666667keywords = dermatosis (Clic here for more details about this article) |
9/11. Bullous dermatosis of chronic renal failure.Four of five patients with chronic renal failure developed tense bullae on the backs of their hands and fingers. In one of these patients the bullae were more widespread. In the fifth patient the lesions were limited to the fingers. The clinical picture resembled that of porphyria cutanea tarda, but porphyrin studies were consistently within normal limits. Histological studies showed subepidermal pressure bullae in each patient. In one of the patients immunohistology showed greenish fluorescence at the bases of the dermal papillae.- - - - - - - - - - ranking = 0.66666666666667keywords = dermatosis (Clic here for more details about this article) |
10/11. Acquired perforating dermatosis and diabetic nephropathy--a case report and review of the literature.A case of acquired perforating dermatosis associated with diabetic nephropathy is described. The case is unusual in that the dermatosis first developed approximately 1 year after renal transplantation rather than at a time when renal function was more severely impaired or during haemodialysis. There was a partial response to treatment with isotretinoin but the use of this drug was limited by the development of hyperlipidaemia. The relevant literature is reviewed.- - - - - - - - - - ranking = 1keywords = dermatosis (Clic here for more details about this article) |
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