Cases reported "Laryngeal Neoplasms"

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1/21. Primary anaplastic giant cell adenocarcinoma of the larynx.

    Anaplastic giant cell adenocarcinoma is an extremely rare tumour arising in the bronchial mucosa. This report describes an example--the first to be reported--of such a tumour evidenced in the subglottic region in a 64-year-old man. Histologically, the tumour resembles that arising in the lung and its morphological characteristics justify a distinction of anaplastic giant cell adenocarcinoma from other types of laryngeal malignant epithelial tumours. As to its histogenesis, the neoplasm is most probably of glandular origin and should be considered as a dedifferentiated adenocarcinoma. The patient, who had undergone total laryngectomy followed by X-ray treatment, is alive one year after surgery.
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2/21. Giant cell tumor of the larynx.

    giant cell tumors are benign tumors generally found in the long bones. Very rarely, they can occur in the larynx and may present with dysphonia, dysphagia, or dyspnea. A case of giant cell tumor of the larynx was recently identified and successfully treated by a partial laryngectomy. A literature review has revealed 18 case reports of giant cell tumor of the larynx. All cases occurred in men. These 19 cases are reviewed, and follow-up data presented where available. There have been no reports of recurrence regardless of treatment, and an excellent prognosis can be expected when one encounters this unusual laryngeal neoplasm.
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3/21. Surgical approach to a giant fibrolipoma of the supraglottic larynx.

    This paper describes the surgical procedures for a fibrolipoma that first appeared as a giant tumour in the hypopharynx and extended to the cardiac antrum of the oesophagus. At the initial surgery, a pedunculated tumour originating from the left arytenoid of the larynx was found to occupy the cervical as well as thoracic oesophagus and was thus removed through a lateral pharyngectomy. A histological examination revealed fibrolipoma. However there was a recurrence of the tumour in the arytenoid and the patient suffered from dysponea. In addition, a submucosal tumour was also found in the left false vocal fold. At the second surgery, the masses in the arytenoid and false vocal fold were subtotally removed without damaging the mucosa. The mucosa of the arytenoid was sutured to the thyropharyngeal muscle on the same side and the arytenoid swelling disappeared almost completely. The post-operative course has been uneventful for more than two years.
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4/21. radiation-induced malignant fibrous histiocytoma of the neck in a patient with laryngeal carcinoma.

    Fibrohistiocytomas are soft tissue tumors of histiocytic origin that have a variety of histological patterns. Although cases of malignant fibrous histiocytoma (MFH) of the head and neck have been reported with increasing frequency in recent years, they are considered rare. We report a case of the giant cell variant of MFH of the neck in which the patient had been given radiotherapy for T1 glottic cancer. prognosis of MFH, the use of radiation as primary treatment, and its role in the development of secondary primary tumors in the head and neck region are reviewed. [editorial comment: The authors stress the important relationship between prior radiation therapy and the induction of new tumors.]
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5/21. Laryngeal giant cell tumour.

    The surgical treatment of an exceedingly rare neoplasm, the laryngeal giant cell tumor, is reported. After removal of the grossly visible part of the growth and reconstruction of the larynx, the lumen of the latter could be preserved by insertion of metal and/or plastic dilator cannulas. Post-operative X-ray treatment has prevented recurrence of the growth throughout the two-year period which has elapsed since the operation.
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6/21. Six cases of children with a benign cervical tumor who required tracheostomy.

    Cervical tumors sometimes cause airway obstruction. We have treated six children with benign cervical tumors who required tracheostomy. Two cervical and one glossal lymphangiomata treated with local injection of OK432 after creating a tracheostomy were successfully decannulated after the treatment. One patient with a giant cervical lymphangioma needed an EXIT (ex utero intrapartum treatment) procedure. He underwent tracheostomy at 10 months of age after long-term endotracheal intubation, but he died of sepsis and hypoxic brain damage at 18 months. One patient with a subglottic hemangioma treated with steroids finally achieved closure of the tracheostomy at 2 years of age. A 7-year-old girl with a tracheal schwannoma underwent tracheostomy performed a week after admission, but she already had hypoxic brain damage resulting from problems with intubation. Most patients with a lymphangioma or hemangioma in the cervical region have required early tracheostomy before commencing treatment with OK-432 or steroids. If there is any sign of possible airway compromise, then it is vital to perform an early tracheostomy, even for benign tumors.
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7/21. adult giant hemangioma of the larynx: a case report.

    We report a giant hemangioma that extended from the mesopharynx to the larynx in an adult. The patient was a 39-year-old woman who had demonstrated an asymptomatic pharyngeal hemangioma since she was 1 year-old. She developed vertigo and consulted a hospital at the age of 39. During screening by head MRI for the diagnosis of the vertigo, hemangioma of the laryngopharynx was detected. She was referred to Osaka National Hospital for further examination. Her subjective symptoms were dyspnoea in the lower left lateral-position. On observation by nasopharyngolaryngovideoscope, a giant hemangioma was diagnosed in the left mesopharynx expanding into the larynx. On MRI study, hemangioma widely extended to the right posterior wall at the mesopharynx level. Since we were concerned about risk of choking if the hemangioma of the larynx were left untreated, we recommended surgery. Under the general anesthesia, hemangioma of the larynx was light-coagulated by KTP laser through tracheotomy. The postoperative-course has been good and at 9 months postoperatively, there was no progression of hemangioma.
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8/21. Laryngeal manifestations of gout.

    gout is a disorder of purine metabolism characterized by hyperuricemia with rare involvement of the head and neck. We present a 72-year-old woman with a known history of gout who presented with hoarseness and a lesion suspicious for carcinoma of the larynx. Endoscopic biopsy revealed a tophus of the true vocal cord with characteristic birefringent crystalline deposits and giant cell granuloma. There have been limited reports of gouty involvement of the larynx, more commonly involving cricoarytenoid arthritis. Tophi of the laryngeal soft tissues are exceedingly rare. In this paper we will discuss the pathophysiology and management of this interesting clinical entity.
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9/21. Cellular whorls in brain tumors other than meningiomas.

    Cellular whorls with or without secondary calcification are generally regarded as reliable diagnostic criteria in the differential diagnosis of meningiomas. They may however occasionally occur in other primary and metastatic brain tumors. Five cases (metastatic laryngeal carcinoma, metastatic mammary carcinoma, metastatic melanoma, medulloblastoma, and giant cell glioblastoma) are presented to illustrate this phenomenon occurring in non-meningothelial brain tumors.
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10/21. Minitracheostomy in elective surgery of the larynx: an alternative to formal tracheostomy.

    A patient scheduled for surgical removal of a giant polyp of the larynx, and in whom difficult orotracheal intubation was anticipated in the preoperative visit, was managed successfully with a minitracheostomy performed with a Mini-Trach II kit. The ventilation achieved was adequate throughout the procedure. Thus, conventional tracheostomy was avoided.
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