1/33. Verruciform xanthoma and concomitant lichen planus of the oral mucosa. A report of three cases.Verruciform xanthomas are benign muco-cutaneous lesions of unknown aetiology. They have a papillated surface and histologically they are characterised by the presence of foam cells in connective tissue papillae between elongated parakeratinised epithelial rete ridges. Three cases are reported in which oral mucosal verruciform xanthoma and oral mucosal lichen planus occurred concomitantly.- - - - - - - - - - ranking = 1keywords = mucosa (Clic here for more details about this article) |
2/33. Patient with lichen planus and conjunctival immunopathologic features of lupus erythematosus.PURPOSE: To report a case of severe cicatricial conjunctivitis in a patient with lichen planus, which is known to affect the skin and mucous membranes. The conjunctival immunopathologic features were consistent with lupus erythematosus rather than with lichen planus. METHOD: Oral mucosal and skin biopsies were performed with histopathologic and immunofluorescent studies consistent with lichen planus. The patient later had a biopsy of cicatrized conjunctiva with histopathologic and immunofluorescent findings consistent with lupus erythematosus. Evaluation by rheumatology and dermatology consultants demonstrated no evidence of active systemic lupus erythematosus or discoid lupus erythematosus. RESULTS: The patient was treated with topical and systemic immunosuppressives and her disease eventually stabilized. CONCLUSION: The case demonstrates two coexisting autoimmune disease entities: lichen planus of the skin and oral mucosa and a cicatricial conjunctivitis consistent with lupus erythematosus.- - - - - - - - - - ranking = 3.79016410227keywords = mucous membrane, mucosa, membrane (Clic here for more details about this article) |
3/33. Oral lichen sclerosus et atrophicus. A case report.lichen sclerosus et atrophicus affecting only the oral mucosa is extremely rare. We report here a case of oral lichen sclerosus et atrophicus presenting as a white, flat lesion involving the right buccal and labial mucosa and vermillion border. The diagnosis was based on histopathologic features. Treatment with intralesional corticosteroid was successful in reducing the size of the lesion and the symptoms of the patient. A free gingival graft was also performed to restore the lost attached gingiva. No recurrence of the lesion was found after a 1-year follow-up period, and no skin or genital lesions developed during the 3 years of treatment.- - - - - - - - - - ranking = 0.33333333333333keywords = mucosa (Clic here for more details about this article) |
4/33. lichen planus--report of successful treatment with aloe vera.lichen planus is a disease that involves the skin and mucous membranes. It is characterized by unique eruptions. The cause of this disease is unknown, but has been linked to emotional stress, and has also been attributed to viral infections. A case is described of a successful treatment of lichen planus.- - - - - - - - - - ranking = 3.4568307689367keywords = mucous membrane, membrane (Clic here for more details about this article) |
5/33. lichen planus with involvement of all twenty nails and the oral mucous membrane.A 57-year-old man had had deformities of all ten fingernails for one and a half years before presentation and deformities of all ten toenails for the previous six months. The surfaces of the nails were rough, with excessive longitudinal striations. The bases of the nails were slightly hypertrophic, and the tips were atrophic and itchy. A longitudinal nail biopsy including the nail matrix revealed the typical histology of lichen planus. Reticulated pigmentation, maceration, and erosion on the buccal mucous membrane were also discovered. Histological analysis of the buccal mucous membrane revealed lichen planus intermingled with eosinophils. Immunological blood analysis revealed elevated CD4 T cells and CD4/CD8 ratio. He worked as a tinsmith and had dental metal. The metal series patch test revealed positive reactions to chromate and tin. Treatment with systemic steroids was quite effective in treating the nail lesions.- - - - - - - - - - ranking = 20.74098461362keywords = mucous membrane, membrane (Clic here for more details about this article) |
6/33. Previous tuberculosis, hepatitis c virus and lichen planus. A report of 10 cases, a causal or casual link?We report 10 cases of lichen planus (LP) and chronic liver disease linked to HCV. The mean age was 63.4 /- 5.1 years (range 51-73), five were female; six patients had an established cirrhosis of the liver, as shown by either a liver biopsy or the ultrasonographic and biohumoral evidence. The remaining four patients had chronic hepatitis. Histological examination confirmed the presence of LP: the localization of the dermatosis was restricted to the skin in four patients, to the mucous membranes in five (4 atrophic erosive and one erosive) while the remaining had mucous-cutaneous localization. A type II cryoglobulinemia was demonstrated in two and a type III in one of the patients, while no one had otherwise circulating autoantibodies (anti-nuclear, anti-smooth muscle, anti-liver kidney microsomal type 1 and anti-mitochondrial antigens) such as other etiological factors of liver disease. In six of the patients the history was positive for previous mycobacterium tuberculosis infection. In clinical practice the patients with chronic liver disease and HCV infection can also suffer from severe extrahepatic manifestations, including lichen planus.- - - - - - - - - - ranking = 3.4568307689367keywords = mucous membrane, membrane (Clic here for more details about this article) |
7/33. Oral mucosal lichenoid reaction to sulfamethoxazole.A clinical case of oral mucosal lichenoid reaction to sulfamethoxazole in a dental patient with complicating medical conditions is described. Although the relationship between oral mucosal lichenoid reaction and sulfa drugs has not been documented previously, the patient's lichenoid reaction corresponded with sulfamethoxazole use, and improved when the drug was discontinued. Reactions of this type should be monitored so that treatment and preventive measures may be instituted.- - - - - - - - - - ranking = 1keywords = mucosa (Clic here for more details about this article) |
8/33. Oral mucosal lichen planus in children.Although lichen planus is a relatively common mucocutaneous disorder in adults, it has only rarely been described in children. Moreover, even less data has been published regarding mucosal lesions in children. Six case reports of childhood oral lichen planus are presented and the available literature reviewed. It is believed that this paper documents the largest series of cases of childhood oral mucosal lichen planus to be reported in the literature to date. lichen planus should be considered in the differential diagnosis of oral mucosal white patches in children, particularly those of Asian origin.- - - - - - - - - - ranking = 1.1666666666667keywords = mucosa (Clic here for more details about this article) |
9/33. Presence of lichen planus during a course of interferon alpha-2a therapy for a viral chronic C hepatitis.We present the case of a 66-year-old woman with a diagnosis of chronic active viral C hepatitis, for whom a course of interferon alpha-2A was prescribed at a dose of 4.5 MU per day for a 2 month period, followed by the same dose on alternate days for 4 months. After completion of a month of therapy, the patient presented with painful oral lesions that made normal oral food intake impossible. These lesions persisted, in spite of withdrawal of interferon therapy. Intraoral examination revealed erosive intraoral lesions in both yugal mucosae, the upper vestibular gum, the floor of the mouth, the ventral region of the tongue, and the lower lip. A diagnosis of erosive lichen planus induced by interferon therapy was established. The prescribed treatment was 0.1% triamcinolone acetonide in orabase applied 3 times a day for 4 weeks. Following the therapeutical course, the erosive lesions disappeared, and the symptoms stopped, although the reticular lesions remained visible.- - - - - - - - - - ranking = 0.16666666666667keywords = mucosa (Clic here for more details about this article) |
10/33. Isolated lichen planus of the lip.lichen planus (LP) is an inflammatory disease that may involve multiple skin sites as well as mucous membranes, hair follicles and nails. It rarely occurs on the lips and usually then in association with oral lesions. We report a 43-year-old man with a 7-month history of inflammation and erosive lesions of the lower lip. Histopathological and immunofluorescence studies showed features of LP. Local treatment with betamethasone dipropionate 0.5% ointment led to complete resolution within 1 month. Four months later, the patient developed typical cutaneous LP. Isolated LP of the lip is unusual, although this condition may be underestimated and therefore under-reported in the literature.- - - - - - - - - - ranking = 3.4568307689367keywords = mucous membrane, membrane (Clic here for more details about this article) |
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