1/16. Superficial mucocele: report of 4 cases.Four cases of the lesion first described as superficial mucocele by Eveson in 1988 are reported. All of the lesions developed in adult women; two of the women had concurrent oral lichen planus. The mucoceles were found on the soft palate, the buccal mucosa, and the upper and lower labial mucosa. The etiologic factors and pathogenesis of this lesion are discussed.- - - - - - - - - - ranking = 1keywords = lichen (Clic here for more details about this article) |
2/16. Associated localization of morphea and lichen planus of the lip in a patient with vitiligo.Morphea, lichen planus and vitiligo are common diseases, but seldom associated. Morphea or lichen planus in the lips have not frequently been reported, and an associated localization of both lesions in the lip mucosa is indeed a rare event. A case of morphea and lichen planus localized in the upper lip mucosa in a patient with vitiligo is reported. immunohistochemistry revealed a clear prevalence of t-lymphocytes in the inflammatory infiltrates of morphea and in the band-like infiltrate of the lichen, a finding consistent with previous reports of morphea, lichen planus, and vitiligo. The inverse ratio found between CD8 and CD4 lymphocytes, compared to other reports, seems to confirm that the pathogenesis of morphea and lichen planus evolves through different stages. The present report, besides presenting a rare case, may prompt to consider a common pathogenesis among morphea, lichen planus and vitiligo.- - - - - - - - - - ranking = 11keywords = lichen (Clic here for more details about this article) |
3/16. Isolated lichen planus of the lip.lichen planus (LP) is an inflammatory disease that may involve multiple skin sites as well as mucous membranes, hair follicles and nails. It rarely occurs on the lips and usually then in association with oral lesions. We report a 43-year-old man with a 7-month history of inflammation and erosive lesions of the lower lip. Histopathological and immunofluorescence studies showed features of LP. Local treatment with betamethasone dipropionate 0.5% ointment led to complete resolution within 1 month. Four months later, the patient developed typical cutaneous LP. Isolated LP of the lip is unusual, although this condition may be underestimated and therefore under-reported in the literature.- - - - - - - - - - ranking = 4keywords = lichen (Clic here for more details about this article) |
4/16. erythema multiforme: a literature review and case report.erythema multiforme is a florid mucocutaneous disease characterized by oral, cutaneous, and ocular manifestations. The cutaneous lesions are pathognomonic because of their unique "target-like" appearance. A severe form of EM has been termed "stevens-johnson syndrome". Although the etiology of EM is unknown, much of the research suggests an immunological association with HSV. The diagnosis of EM is based on signs and symptoms, and a differential diagnosis should include other ulcerative, mucocutaneous diseases, such as erosive lichen planus, pemphigus, varicella zoster, ANUG, TEN, aphthous stomatitis, and primary HSV. Therapeutic measures are palliative, including a soft bland diet, topical anesthetics, and corticosteroids. A case of EM is described which underscores the appearance of the disease and its clinical course.- - - - - - - - - - ranking = 1keywords = lichen (Clic here for more details about this article) |
5/16. lichen sclerosus et atrophicus of the oral mucosa.lichen sclerosus et atrophicus (LSA) is a chronic, benign, depigmenting disease of the skin and mucous membranes most frequently affecting the female genitalia. Involvement of the oral mucosa without concurrent genital or skin lesions has been reported only occasionally in the literature. In view of the rarity of reported cases, one lesion affecting only the labial mucocutaneous area is presented along with a description of the disease's clinical and histopathological findings.- - - - - - - - - - ranking = 4.8487816601737keywords = sclerosus (Clic here for more details about this article) |
6/16. Cutaneous and oral eruption from oral exposure to nickel in dental braces.Oral eruptions due to nickel allergy are rare. A common presentation of intraoral contact dermatitis is the presence of lichenoid plaques on the buccal mucosa adjacent to the offending antigen. We report an unusual case of cutaneous and mucosal nickel allergy arising after placement of dental braces. An 11-year-old boy was referred by his orthodontist to the University of minnesota Occupational and Contact dermatitis Clinic to be evaluated for a possible metal allergy. The patient developed an itchy rash on his abdomen and under his wristwatch 1 week after dental braces were placed. He was diagnosed with allergic contact dermatitis from nickel. The patient avoided cutaneous nickel exposure and had a minimal resolution of his symptoms. One year later, the patient developed swelling and burning of the lips. Secondary to extreme discomfort, the braces, which contained nickel, titanium, and zinc, were removed. The patient underwent standard patch testing; the final reading at 96 hours showed a reaction to nickel, palladium, cobalt chloride, and neomycin. The patient experienced relief of his oral symptoms after removal of the braces. No current relevance to palladium, cobalt, or neomycin has been found.- - - - - - - - - - ranking = 1keywords = lichen (Clic here for more details about this article) |
7/16. Development of lichen planus and psoriasis on lesions of vitiligo vulgaris.This paper reports a unique case of coexistence of vitiligo vulgaris, lichen planus and psoriasis vulgaris in a 53-year-old man. Five years after the onset of vitiligo, lichen planus developed on his lower lip. Another 4 years after the onset of lichen planus, he also exhibited psoriasis on his upper arms and trunk. Both the lichen planus and psoriasis occurred on lesions of the preceding vitiligo vulgaris. We discuss potential mechanisms for association of these three dermatoses, including Koebner phenomenon and photodamage.- - - - - - - - - - ranking = 8keywords = lichen (Clic here for more details about this article) |
8/16. Paraneoplastic pemphigus mimicking erosive mucosal lichen planus associated with primary hepatocellular carcinoma.A 58-year-old Japanese male visited us with painful lesions on the lower lip, oral mucosa and genital region of an 8-month duration. Histological features of the genital lesion were almost consistent with lichenoid tissue reaction. A few intraepidermal acantholytic keratinocytes were also seen in the suprabasal clefts. Direct immunofluorescence exhibited cell surface immunoglobulin (Ig)G deposition and linear deposition of fibrinogen at the dermoepidermal junction. IgG anti-desmoglein (Dsg)3 antibody, but not anti-Dsg1 antibody, was detected in the patient's serum by enzyme-linked immunosorbent assay. immunoblotting using normal human epidermal extract detected the 210-kD envoplakin, 190-kD periplakin and 130-kD Dsg3. The diagnosis of paraneoplastic pemphigus (PNP) was made. Subsequent investigation revealed a large space-occupying lesion in the liver. Histological findings from liver biopsy specimen were consistent with hepatocellular carcinoma. The patient has been alive 38 months after the diagnosis of PNP was made, although the liver mass has slowly enlarged. Our case is clinically and histologically similar to erosive mucosal lichen planus. Immunological studies confirmed the diagnosis of PNP. The results of negative Dsg1 and positive Dsg3 were consistent with clinical features showing severe mucosal involvement without cutaneous erosion. In PNP, the association with non-hematological solid tumor is extremely rare.- - - - - - - - - - ranking = 6keywords = lichen (Clic here for more details about this article) |
9/16. Chronic mucocutaneous candidiasis-thymoma syndrome. A case report.A 69-year-old woman sought treatment with a history of persistent debilitating intraoral ulcerations and recurrent oral and vaginal candidiasis. The medical history included thymoma, breast cancer, and lip cancer. The oral lesions were consistent with bullous lichen planus. Laboratory studies showed severe hypogammaglobulinemia. The chronic mucocutaneous candidiasis-thymoma syndrome is now recognized as a distinct form of primary immunodeficiency.- - - - - - - - - - ranking = 1keywords = lichen (Clic here for more details about this article) |
10/16. Isolated lichen planus of the lip.Oral lichen planus (LP) is a relatively common disorder of unknown aetiology. Oral LP occurs most often on the buccal mucosa, but the gingivae, tongue, floor of the mouth, retromalar pads and lips may also be affected. Usually, patients have multiple sites of involvement. We report a 44-year-old patient with a 3-year history of isolated swelling of the lower lip, erosions and crusting. histology of a biopsy from the lip revealed features of LP. Oral treatment with acitretin and low-dose steroid led to complete resolution of the lesions within 10 weeks. This is the first well-documented case of isolated LP of the lip. Diagnostic difficulties and differential diagnosis are reviewed.- - - - - - - - - - ranking = 5keywords = lichen (Clic here for more details about this article) |
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