1/57. Multiple canalicular adenomas: a case report and review of the literature.The canalicular adenoma is an uncommon, benign salivary gland tumor that most frequently occurs in the upper lip. Rarely, it manifests itself clinically and histologically as a multifocal lesion, a feature not generally seen with other intraoral salivary gland tumors. Here we report a case of canalicular adenoma that manifested itself with 13 clinically discrete tumor masses involving the upper lip and anterior buccal mucosa. In addition to the clinical nodules, there were microscopic foci of tumor cells in the adjacent normal-appearing salivary gland tissue surrounding the tumors. This article also reviews previously reported multifocal canalicular adenomas and discusses their features, emphasizing differences in the reported growth patterns of this unusual tumor.- - - - - - - - - - ranking = 1keywords = adenoma, gland (Clic here for more details about this article) |
2/57. sweat gland carcinoma of the lips.sweat gland carcinomas are extremely rare tumors with a fully malignant potential. Two cases of primary sweat gland carcinoma of the lips are presented. Because of the unique nature of this lesion, the histopathology and biologic behavior are discussed, and the pertinent literature is reviewed.- - - - - - - - - - ranking = 1.6013878192845keywords = sweat gland, sweat, gland (Clic here for more details about this article) |
3/57. Sebaceous lymphadenoma of the lip: report of a case of minor salivary gland origin.A case of sebaceous lymphadenoma occurring in the lip of a 73-year-old female is described. The patient had noticed a painless mass in the region of her upper lip for a year. The surgically removed tumor, measuring about 10 mm in diameter, was located just beneath the lip mucosa, expanding into the submucosal and muscle layer. Histologically, the tumor was well encapsulated and consisted of scattered round-shaped islands of small squamous epithelial cells with focal but apparent sebaceous differentiation in a background of lymphoid stroma. This is the first case report of sebaceous lymphadenoma of minor salivary gland origin.- - - - - - - - - - ranking = 1.0462750966775keywords = adenoma, gland (Clic here for more details about this article) |
4/57. Malignant melanoma of the lip spreading in a pagetoid manner into the minor salivary glands.We describe a malignant melanoma of the lower lip that upon recurrence extended in a pagetoid manner into the ducts of the oral minor salivary glands. immunohistochemistry with antibodies to MART-1 and HMB-45 confirmed that the atypical cells in the ducts of the salivary glands were indeed melanoma cells. Pathologists involved in staging of oral melanoma are urged to look out for this previously unreported mode of spread of labial malignant melanoma.- - - - - - - - - - ranking = 0.46726788590914keywords = gland (Clic here for more details about this article) |
5/57. carney complex: report of a Japanese case associated with cutaneous superficial angiomyxomas, labial lentigines, and a pituitary adenoma.We report the case of a 12-year-old female patient who manifested multiple cutaneous angiomyxomas and labial pigmented lesions. Although the familial history was not confirmed in the present case, autosomal dominant inheritance has been reported to be involved in the pathogenesis of this condition. In addition to the cutaneous complications, magnetic resonance (MR) images revealed the presence of a pituitary adenoma, which provoked an elevation of serum growth hormone (GH) level. On the other hand, no significant symptoms such as cardiac myxoma, myxoid fibroadenoma of the breast, or adrenocortical complaints suggesting cushing syndrome, were detected. In the Japanese literature, only a few cases of this disorder have been described in the form of brief reports. There have been only a few similar cases described in the dermatological field, except for one report diagnosed as carney complex in 1990. Therefore, the present case seems to be the first Japanese case of typical carney complex manifesting major clinical complications, including angiomyxomas, lentigines, and a pituitary adenoma, which induced endocrine overactivity.- - - - - - - - - - ranking = 0.76636605704543keywords = adenoma (Clic here for more details about this article) |
6/57. Widespread cutaneous and perioral metastases of mesothelioma.BACKGROUND: Cutaneous involvement by mesothelioma represents a rare occurrence from an uncommon neoplasm. Most cases have resulted from local extension of an underlying body cavity mesothelioma or from surgical site contamination. We could only find six previously reported cases of distant cutaneous metastases of mesothelioma. methods: We describe a case of metastatic mesothelioma involving multiple skin sites and the lip in a 64-year-old man with an underlying primary pleural mesothelioma. RESULTS: A 64-year-old man presented with a lip lesion clinically diagnosed as keratoacanthoma vs. squamous cell carcinoma. Evaluation of the lip biopsy revealed tubulo-glandular and acinar-like arrangements of plump epithelioid cells with a hobnailed appearance, vesicular nuclei, and prominent nucleoli. The initial impression of metastatic carcinoma was revised to probable mesothelioma upon discovery of a previous history of pleural mesothelioma. Positive immunohistochemical stains for anti-cytokeratin, anti-calretinin, and HBME-1 and negative stains for anti-CEA, Leu-M1, B72.3, and Ber-Ep4 confirmed the diagnosis. CONCLUSION: We report a rare example of multiple cutaneous metastases of mesothelioma. We also demonstrate the usefulness of relatively new and specific immunomarkers for mesothelioma vs. adenocarcinoma. Metastatic mesothelioma to the skin or lip is a very rare occurrence but should be considered in the differential diagnosis of malignant epithelioid neoplasms.- - - - - - - - - - ranking = 0.077877980984857keywords = gland (Clic here for more details about this article) |
7/57. Adenomatosis of minor salivary glands. Report of a case.An account is given of a patient who had multiple canalicular adenomas in the upper lip and adjacent oral mucosa. A few months after these had been excised, several more tumors of the same type developed. Microscopic examination also revealed numerous tiny foci of adenomatous proliferation within otherwise normal salivary gland lobules. We suggest that this phenomenon represents a field neoplastic change although it appears to be benign.- - - - - - - - - - ranking = 0.60835163550869keywords = adenoma, gland (Clic here for more details about this article) |
8/57. Papillary cystadenoma arising from the upper lip: a case report.We report a rare case of a papillary cystadenoma arising from the upper lip. This tumor was not distinctly encapsulated and had proliferated replacing the ductal epithelium. mast cells were found not only in the stroma but also in the oncocytic epithelial layer. There was a strong immunoreaction with mitochondrial antibody in the epithelial layer. Only one case (0.9%) of papillary cystadenoma has occurred among the 110 benign intraoral salivary gland tumors seen in our hospital from 1966 through September 2003.- - - - - - - - - - ranking = 0.73476317273808keywords = adenoma, gland (Clic here for more details about this article) |
9/57. Canalicular adenoma of the upper lip mimicking mucocele.salivary gland neoplasms are relatively rare. Among the salivary gland neoplasms minor salivary gland neoplasms are often deceptive to the clinician and challenging to the pathologist because of their varied morphology and diverse histopathological pattern. This article documents a case of canalicular adenoma of the upper lip mimicking mucocele and discusses the differential diagnosis of minor salivary gland neoplasms.- - - - - - - - - - ranking = 0.85891625040045keywords = adenoma, gland (Clic here for more details about this article) |
10/57. Canalicular adenoma arising in the upper lip: review of the pathological findings.This case report describes a rare case of canalicular adenoma arising in the upper lip of a 61-year-old male patient. Macroscopic examination of the tumor revealed a well-defined, smooth, firm, elastic hard, round nodule with a diameter of 1.0 cm. The cut surface was white. Histopathology showed that the tumor was an encapsulated mass with a complex cellular pattern of anastomosing duct-like or trabecular structures lined by a single layer of tall columnar epithelial cells, which were embedded in a loose, fibrous, and highly vascular connective tissue stroma. The tumor cells were immunoreactive to AE1/AE3, CK19 and S-100, were partially positive for CK7, CK8, GFAP and PCNA, but were negative for SMA, CK13, CK14 and vimentin.- - - - - - - - - - ranking = 0.54740432646102keywords = adenoma (Clic here for more details about this article) |
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