1/38. Neural compressive symptoms appearing during steroid treatment in a patient with intracranial lipoma.Intracranial lipoma is a rare condition, and it is usually asymptomatic. We describe a 67 year old woman who developed blurred vision, diplopia, left sided oculomotor palsy, and ipsilateral ptosis during steroid treatment for giant cell arteritis. These symptoms were considered to be associated with aggressive giant cell arteritis, and the steroid dose was raised. Surprisingly, the symptoms increased, and further examination revealed an intracranial lipoma situated in the Meckel's cave. During tapering of the steroids her symptoms gradually improved. This is the first report demonstrating that steroids may induce hypertrophy of the fat tissue in the intracranial lipoma, causing compression of the cranial nerves passing through the cavernous sinus thereby mimicking the ocular symptoms sometimes associated with aggressive giant cell arteritis.- - - - - - - - - - ranking = 1keywords = hypertrophy (Clic here for more details about this article) |
2/38. Squamous cell carcinoma and lipomatous pseudohypertrophy of the pancreas.A 68-year-old woman who had been treated for non-insulin-dependent diabetes mellitus for the past 20 years was admitted to hospital because of abdominal pain and weight loss. Radiological investigation revealed a tumour in the body of the pancreas and numerous intraductal calcifications in both the tail and the head of the pancreas. Left-sided pancreatectomy was performed to remove the tumour. The resection specimen showed fatty enlargement of the parenchyma and numerous intraductal calcifications in the tissue adjacent to the tumour, which was 7 cm in diameter and was found to be a primary squamous cell carcinoma with a spindle cell component. There was also lipomatous pseudohypertrophy.- - - - - - - - - - ranking = 5keywords = hypertrophy (Clic here for more details about this article) |
3/38. Surgical management of extensive lipomatous hypertrophy of the right atrium.Lipomatous hypertrophy of the right atrium is a rare lesion that is usually limited to the interatrial septum. The authors report on a patient that suffered from an extensive lipomatous hypertrophy, which protruded into the right and left atrium as well as the superior vena cava and caused inflow obstruction. Therapeutic management is discussed.- - - - - - - - - - ranking = 6keywords = hypertrophy (Clic here for more details about this article) |
4/38. A t(2;19)(p13;p13.2) in a giant invasive cardiac lipoma from a patient with multiple lipomatosis.Cardiac lipomas occur infrequently but account for a significant portion of rare cardiac tumors. Common cutaneous lipomas have previously been associated with rearrangements of chromosome band 12q15, which often disrupt the high-mobility-group protein gene HMGIC. In this report, we describe the cytogenetic analysis of an unusual giant cardiac lipoma that exhibited myocardial invasion in a patient with a history of multiple lipomatosis (cutaneous lipoma, lipomatous gynecomastia, lipomatous hypertrophy of the interatrial septum, and dyslipidemia). Cytogenetic studies of cells derived from the cardiac lipoma demonstrated no abnormalities of chromosome 12, but did reveal a t(2;19)(p13;p13.2). A liposarcoma-derived oncogene (p115-RhoGEF) previously mapped to chromosome 19 and the low-density lipoprotein receptor gene (LDLR) previously mapped to chromosome band 19p13 were evaluated to determine whether they were disrupted by this translocation. fluorescence in situ hybridization analyses assigned p115-RhoGEF to chromosome 19 in bands q13.2-q13.3 and mapped the LDLR to chromosome arm 19p in segment 13.2, but centromeric to the t(2;19) breakpoint. Thus, these genes are unlikely to be involved in the t(2;19)(p13;p13.2). Further studies of the regions of chromosomes 2 and 19 perturbed by the translocation in this unusual infiltrating cardiac lipoma will identify gene(s) that participate in adipocyte growth and differentiation and may provide insight into syndromes of multiple lipomatosis.- - - - - - - - - - ranking = 1keywords = hypertrophy (Clic here for more details about this article) |
5/38. Two- and three-dimensional TEE differentiation of lymphoma involving the atrial septum from lipomatous hypertrophy.In this case report we present two-dimensional (2-D) and three-dimensional (3-D) transesophageal echocardiographic (TEE) findings of a patient with lipomatous atrial septal hypertrophy and a patient with Hodgkin's lymphoma with atrial septal involvement. The echocardiographic characteristics that differentiate these two lesions are discussed.- - - - - - - - - - ranking = 5keywords = hypertrophy (Clic here for more details about this article) |
6/38. Lipoma of the heart: a case report.Lipomas of the heart are rare (only 0.5% according to the Armed Forces Institute of pathology series) and their diagnosis is often difficult because they are asymptomatic; in fact, in contrast to lipomatous hypertrophy, lipomas are usually found on the epicardial surfaces of the atria or ventricles. In our case, the lipoma was located in both atria and was attached to the interatrial septum involving also the right pulmonary veins, the inferior vena cava and the right phrenic nerve. At histology, the tumor was composed only of mature adipose tissue with entrapped myocytes and vessels. The combination of computed tomography and transesophageal echocardiography allowed a precise diagnosis in terms of the localization and tissue characterization of the tumor.- - - - - - - - - - ranking = 1keywords = hypertrophy (Clic here for more details about this article) |
7/38. proteus syndrome.proteus syndrome is a rarely described dysplasia syndrome of the group of congenital hamartomas that arises from mosaic mutation. An extraordinary case history including imaging studies will be reported. This 17-year-old girl suffered from cachexia, lifelong chronic obstipation, different dysplasias, and lipomatous tumor-like lesions. The following findings were marked: macrodactyly, nevi, hemihypertrophy, aggressive lipomatosis, hemangiomas of the spleen, and skull and cerebral malformations. Additionally, an intestinal affection with fatty wall thickening was detected. In contrast to reports in the literature describing a reduced lifespan with a mean of few years, our patient is still alive. The treatment should take a palliative symptomatic approach considering the clinical situation.- - - - - - - - - - ranking = 1keywords = hypertrophy (Clic here for more details about this article) |
8/38. Lipomatus hypertrophy of the atrial septum and prominent crista terminalis appearing as a right atrial mass.In these case reports, transthoracic echocardiography suggested the presence of a right atrial mass. However, subsequent transoesophageal echocardiography revealed that the 'right atrial mass' was actually a lipomatous hypertrophied atrial septum in combination with a prominent crista terminalis. An understanding of the anatomy and the echocardiographic appearance of a lipomatous hypertrophied atrial septum appearing with a prominent crista terminalis will minimize the misdiagnosis of these structures.- - - - - - - - - - ranking = 4keywords = hypertrophy (Clic here for more details about this article) |
9/38. Surgical conservative treatment for Bauhin's syndrome.BACKGROUND AND STUDY AIMS: hypertrophy of ileocaecal sphincter seems to be the basic etiological factor of Bauhin's valve syndrome (BVS). In the rare literature all cases are treated by means of an hemicolectomy. A patient with Bauhin's valve syndrome is described, whose pathologic characteristics were hypertrophy of ileocaecal sphincter and a circular submucosal lipoma on the caecal side of the valve. Lipomata, although uncommon, may arise throughout the whole gastrointestinal tract, mostly asymptomatic, and submucosal layer is most frequently involved than subserosal one. More than two-thirds of gut lipoma are found in the large bowel, where they represent the most common benign lesion after adenoma. patients AND methods: A 36 year old woman suffering from periodic upper abdominal pain, nausea and diarrhea, was submitted to an explorative surgical procedure, after imaging study of the bowel showed only an indistict mass in the caecum. Though a caecotomy a dissection of an hypertrophic and swollen portion of the ileocaecal valve was performed, saving the ileo-caecal sphincter. The residual mucosal margins were sutured, the last tract of the ileum was fixed to the caecum, completing with a caecorrhaphy and appendectomy. RESULTS: Normal post-operative period, discharging the patient after few days. Since the operation all symptoms disappeared, and after four years there is a total well-being of the patient with complete disappearance of the former symptoms. CONCLUSIONS: If the BVS is only due to a lipomatous hypertrophy of the mucosa and submucosa of ileo-caecal valve, hemicholectomy seems to be not justified: it is an exceedingly invasive procedure for a non-malignant disease. It is important a throughout radiological diagnosis and a caecotomy direct control during an operative exploration for a correct surgical choice.- - - - - - - - - - ranking = 2keywords = hypertrophy (Clic here for more details about this article) |
10/38. Lipomatous hypertrophy of the interatrial septum and upper right atrial inflow obstruction.Lipomatous hypertrophy of the heart is a benign rare abnormality characterized by large fatty tissue deposits in the interatrial septum. An increased incidence of atrial arrhythmias is described in these patients, significant blood flow obstruction however is not the rule. We report a case of lipomatous hypertrophy of the interatrial septum, detected by transeosophageal echocardiography (TEE). The tumour mass protruded into the right atrium and the superior caval vein (SCV), thus causing upper right atrial inflow obstruction. Partial resection of the tumour and pericardial patch-reconstruction of the SCV were performed in combination with coronary artery bypass grafting due to coronary artery disease (CAD). The diagnostic and therapeutic management is discussed and a review of the literature performed.- - - - - - - - - - ranking = 6keywords = hypertrophy (Clic here for more details about this article) |
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