1/6. Metastasizing mixed tumour of the parotid gland presenting as multiple lung metastases.Metastasis is a feature of malignant neoplasms. Although rare, metastasizing pathologically benign mixed tumour has been reported. This report describes a 33-year-old woman with multiple lung metastases from mixed tumour. A small preauricular mass had been removed 23 years earlier. Six years later, the patient had the same symptom; the recurrent mass was resected. She was not aware of the exact pathological diagnosis of the previous tumours. One of the most common features of metastasizing mixed tumour is recurrence at the primary site. Inadequate resection of the primary tumour is often associated with metastasis. Thus, it is important for the head and neck surgeon to be aware of the concept of pathologically benign metastasizing mixed tumour and the importance of adequate surgical procedure.- - - - - - - - - - ranking = 1keywords = mixed tumour (Clic here for more details about this article) |
2/6. Mixed tumours of the lung: a report of three cases.Three patients with mixed tumours of the lung are presented. The difficulties making a histological diagnosis are stressed and the value of extensive examination of large amounts of tissue, and electron microscopy is emphasized.- - - - - - - - - - ranking = 0.125keywords = mixed tumour (Clic here for more details about this article) |
3/6. Unusual tumours of the lung.Unusual lung tumors are not simply pathological curiosities. They demonstrate features of major significance in diagnosis, treatment, and prognosis. Six of these tumours are discussed: (1) carcinosarcoma is rarely found in the lung. The histogenis of the lesion is unclear and the prognosis is poor. (2) Only three cases of pleomorphic adenoma have previously been described. Differentiation from other "mixed tumours" of the lung is essential. (3) A rare case of bronchial adenoma producing ectopic ACTH is described. Early recognition of these polypeptide hormone-secreting tumours is stressed. (4) Oat cell carcinoma with the myasthenic (Eaton-Lambert) syndrome shows the clinical features which should permit early tumour diagnosis. The hazards of muscle relaxants must be recognized. (5) Prostatic carcinoma with endobronchial metastases is is discussed. The importance of localization of the primary tumour is emphasized. (6) An example of double primary carcinoma is presented. The rarity of this finding may be related to the poor prognosis of patients with bronchogenesis carcinoma.- - - - - - - - - - ranking = 0.125keywords = mixed tumour (Clic here for more details about this article) |
4/6. Is sclerosing hemangioma of lung an alveolar mixed tumour?A case of a peripheral lung tumour histologically categorized as a sclerosing hemangioma of the lung is presented. Ultrastructurally, the tumour is composed of a mixture of epithelial and mesenchymal elements in varying stages of differentiation. Type II pneumocytes are identified as one epithelial component, while primitive mesenchymal cells with a tendency to develop into pericytes are the predominant mesenchymal component. The tumour appears to differentiate along the line of the pulmonary alveolar septa, and should be designated as a 'pulmonary alveolar mixed tumour'.- - - - - - - - - - ranking = 0.625keywords = mixed tumour (Clic here for more details about this article) |
5/6. adenocarcinoma of the colon with choriocarcinoma in its metastases.A 49-year-old woman died from metastases from a colon carcinoma. This was predominantly an ordinary tubular adenocarcinoma but it included arease of much less differentiated appearance with giant cells, while the hepatic and pulmonary metastase were poorly differentiated and contained choriocarcinoma, as established by means of morphologic and immunocytochemical examination. The choriocarcinoma appeared to be due to metaplasia within the carcinomatous tissue. This and other similar cases of mixed tumours suggest that unexpected trophoblastic differentiation may result from aberrant differentiation of locally proliferating cells, rather than originating in ectopic germ cells or in foci of embryonic totipotent cells. Implications for possible origin and for classification of tumors are briefly discussed.- - - - - - - - - - ranking = 0.125keywords = mixed tumour (Clic here for more details about this article) |
6/6. pulmonary blastoma.pulmonary blastoma is now accepted as a distinctive neoplasm. It remains rare, and only 28 cases have been reliably recorded. A further two cases are now reported, and the previous literature is reviewed. There are no specific clinical or radiological features of pulmonary blastoma. The presentation can be that of any other pulmonary tumour although a peripheral situation is usual and a large size is often attained before detection. pulmonary blastoma is a mixed tumour with malignant epithelial and connective tissue components with a distinctive resemblance to fetal lung. The treatment of choice is surgical excision but the overall prognosis is poor. It is doubtful whether the tumour has a true blastomatous origin.- - - - - - - - - - ranking = 0.125keywords = mixed tumour (Clic here for more details about this article) |