1/50. Bronchopulmonary and mediastinal leishmaniasis: an unusual clinical presentation of leishmania donovani infection.We describe a case of unusual leishmaniasis in a Sudanese man with a history of progressively enlarging granulomatous mediastinal lymphadenopathy, worsening hemoptysis, and an intense mucosal granulomatous inflammatory response in the large bronchi. leishmania donovani dna was detected in bronchial biopsies by polymerase chain reaction. This is a novel description of human leishmanial infection in an immunocompetent patient involving this anatomical site. The patient's condition improved clinically, spirometrically, and radiologically after a course of treatment with amphotericin b. The cell-mediated immune response was analyzed before, during, and after successful antileishmanial chemotherapy.- - - - - - - - - - ranking = 1keywords = leishmaniasis (Clic here for more details about this article) |
2/50. Lymphatic leishmaniasis--first case report from nepal.We report a case of exclusive involvement of lymph node in leishmaniasis presenting as generalized lymphadenopathy. The diagnosis of lymphatic leishmaniasis was confirmed by the presence of leishmania donovani body in fine needle aspiration cytology, positive direct agglutination test and anti-rK39 antibodies. The bone marrow aspiration was negative for leishmania donovani body. This is the first case of lymphatic leishmaniasis reported from nepal.- - - - - - - - - - ranking = 1.4keywords = leishmaniasis (Clic here for more details about this article) |
3/50. Infantile periarteritis nodosa or mucocutaneous lymph node syndrome. A report on four cases and diagnostic considerations.Coronary artery aneurysm in childhood is a rare disease and has in most cases been ascribed to infantile periarteritis nodosa (IPN). In recent years a mucocutaneous lymph node syndrom (MLNS) has been found almost exclusively in japan first described by Kawasaki 1967; this disease frequently involves the coronary arteries and myocardium. Four cases with coronary aneurysms are presented from sweden and seem to be first described from scandinavia. Three of these patients died a sudden death with cardiac arrest. Since MLNS and IPN have identical clinical and pathological features, we suggest that MLNS and IPN constitute a pathologic entity and that to separate them on a clinical or histological basis is nonsensical. The risk of coronary aneurysm and possible sudden death must be considered in patients with uncharacteristic symptoms including prolonged fever, conjunctivitis, exanthema, lesions in the oral mucosa, elevated sedimintation rate, and leukocytosis.- - - - - - - - - - ranking = 4.2720622569019keywords = mucocutaneous (Clic here for more details about this article) |
4/50. Sinus histiocytosis with massive lymphadenopathy Rosai-Dorfman: three unusual manifestations.We report on three exceptional courses of sinus histiocytosis Rosai-Dorfman. Patient one developed regional lymph-node disease subsequent to two independent malignancies in the right head and neck region. Patient two suffered from extensive extranodal disease with more than 100 mucocutaneous lesions over 17 years, which spontaneously resolved. Patient three showed exclusively extranodal disease, including bilateral conjunctival/scleral lesions, before he developed lung cancer. Our cases are unique for three reasons: the association of the disease with solid malignancies in two cases, the extent and persistence of exclusively extranodal disease in one patient and the appearance of thus far undescribed conjunctival/scleral lesions.- - - - - - - - - - ranking = 0.85441245138039keywords = mucocutaneous (Clic here for more details about this article) |
5/50. Lymphatic leishmaniasis. An adult case without visceral involvement from Sharkia Governorate, egypt.Lymphatic leishmaniasis was reported as an indigenous infection in a 30 year old male from Abo Hamad, Sharkia, egypt. Cervical lymphadenopathy was the only clinical sign and no visceral involvement. diagnosis was based on histopathological examination of needle biopsied material. The patient was successfully treated with sodium stibogluconate as shown clinically and parasitologically. It was concluded that lymphatic leishmaniasis should be in mind when dealing with lymphanopathy of unknown aetiology.- - - - - - - - - - ranking = 1.2keywords = leishmaniasis (Clic here for more details about this article) |
6/50. Atypical American visceral leishmaniasis caused by disseminated Leishmania amazonensis infection presenting with hepatitis and adenopathy.Leishmania amazonensis is widely recognised as a cause of cutaneous leishmaniasis in latin america, but it can also disseminate to produce atypical visceral leishmaniasis with hepatitis and lymphadenopathy. The patient, an 8-year-old Brazilian boy, presented with a febrile illness and hepatosplenomegaly, elevated liver enzymes and generalised adenopathy. Serological tests using antigens of L. chagasi, the typical cause of visceral leishmaniasis in latin america, were inconclusive. Leishmania amazonensis was eventually isolated in a culture of a lymph node. The patient recovered fully after treatment with meglumine antimoniate. As this case illustrates, L. amazonensis produces a spectrum of disease that includes atypical American visceral leishmaniasis with evidence of hepatocellular injury and generalised lymphadenopathy.- - - - - - - - - - ranking = 1.6keywords = leishmaniasis (Clic here for more details about this article) |
7/50. Aneurysms of the coronary arteries in infants and children. A review, and report of six cases.In recent years large numbers of the so-called "mucocutaneous lymph node syndrome" or "Kawasaki's disease" have been described by Japanese workers, but instances of this disorder are only now being reported as isolated cases by European or North American physicians. The disease has, therefore, been considered to be a new entity. One of its most striking features is the development of aneurysms of the coronary arteries in infants or children, which may lead to sudden death. Aneurysms of the coronary arteries in childhood are rare, and hence it was considered relevant to report six such cases, and to examine their possible relationship to Kawasaki's disease. The pathological changes underlying the latter disorder are not well known; they are considered to be indistinguishable from infantile polyarteritis nodosa. A diagnosis of polyarteritis nodosa was also thought to be most likely to apply in the cases presented here, particularly in view of the frequency with which aneurysms of the coronary arteries have been found in this disorder. In the absence of valid pathological distinctions between Kawasaki's disease and infantile polyarteritis nodosa, the question arises whether these entities are, in fact, different, and whether Kawasaki's disease is the new entity it is assumed to be.- - - - - - - - - - ranking = 0.85441245138039keywords = mucocutaneous (Clic here for more details about this article) |
8/50. Lymphatic leishmaniasis associated with visceral leishmaniasis.Lymphatic leishmaniasis associated with visceral leishmaniasis is rare in india. We are reporting one such case, which is the first case reported so far from Bihar.- - - - - - - - - - ranking = 2keywords = leishmaniasis (Clic here for more details about this article) |
9/50. Simultaneous surgical treatment of tetralogy of fallot and coronary artery aneurysm due to mucocutaneous lymph node syndrome in a 4-year-old child.The simultaneous correction of tetralogy of fallot and an aneurysm of the coronary artery due to mucocutaneous lymph node syndrome (MCLS) in a 4-year-old boy was successfully performed. Of the four aneurysms found on the coronary angiogram at the age of six months, the smaller three regressed spontaneously leaving slight dilatation and thickening of the arterial wall during the 4-year follow-up period. However, the largest one in the right coronary artery, which remained almost the same size, showed marked stagnation of blood in the aneurysm with the possibility of thrombosis and resultant myocardial infarction. At operation, there was a large aneurysm in the right coronary artery, 9 mm in width and 18 mm in length. The wall of the aneurysm was very thick and tightly adherent to the myocardium. The aneurysm was resected and an aorto-coronary bypass graft was fashioned from a saphenous vein taken from the patient's mother, since an autogenous vein was not available. A ventricular septal defect was closed and pulmonary stenosis was relieved without any difficulty. Postoperative cardiac catheterization and coronary angiography four weeks after the operation revealed satisfactory correction of the tetralogy of fallot and a patent aorto-coronary vein graft. Several problems regarding surgical treatment of coronary artery aneurysm due to MCLS are discussed.- - - - - - - - - - ranking = 4.2720622569019keywords = mucocutaneous (Clic here for more details about this article) |
10/50. CT findings in visceral leishmaniasis mimicking lymphoma.A case of visceral leishmaniasis (Kala-Azar) is presented which clinically and on CT examination mimicked lymphoma. The value of the recognition of the previously unreported CT findings of visceral leishmaniasis is discussed.- - - - - - - - - - ranking = 1.2keywords = leishmaniasis (Clic here for more details about this article) |
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