Cases reported "Malaria, Vivax"

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1/3. Acute respiratory distress syndrome complicating plasmodium vivax malaria.

    malaria is one of the most common infectious diseases in the world, and severe respiratory complications have been described mainly in association with plasmodium falciparum. We describe a case of acute respiratory distress syndrome complicating infection with P. vivax in the setting of relatively low parasitemia in a 47-yr-old woman after a brief trip to papua new guinea. A review of the literature shows that pulmonary complications of P. vivax are rare but occur more frequently than generally acknowledged. Pathogenic mechanisms of these complications are discussed.
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2/3. Abnormal leukocyte histogram with a factitious automated white cell count due to plasmodium vivax parasitemia--a case report.

    Automated hematology analyzers are designed to produce accurate and precise blood counts on specimens which are either normal or show only numerical abnormalities. However they alert the operator in samples with unusual characteristics which could result in inaccurate measurement or require review of the blood smear. Even the most sophisticated instruments cannot recognize all the significant abnormalities that can be recognized by a human observer. Spurious automated white cell counts could result from platelet aggregates, nucleated red cells, non lysis of cells and a variety of other causes. We present a case with spurious leukocytosis due to plasmodium vivax parasitemia which was flagged by the automated analyzer.
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3/3. Studies on a primaquine-tolerant strain of plasmodium vivax from brazil in Aotus and saimiri monkeys.

    A nonimmune American acquired an infection of plasmodium vivax Type 1 malaria in brazil in 1994. After returning to the U.S.A., he had a primary attack followed by 3 relapses. The primary attack and first 2 relapses were treated with a standard regimen of chloroquine, followed by 14 days of primaquine (15 mg/day). Following the third relapse, the primaquine treatment was extended to 28 days. No further relapses occurred. The lack of response to primaquine by this strain may recommend it as a suitable candidate for chemotherapeutic study if it can be adapted to an animal model. Anopheles quadrimaculatus mosquitoes infected by feeding on the patient during the first relapse were used to establish the strain in Aotus and saimiri monkeys. Monkeys supported well the development of long-lasting parasitemia. Anopheles freeborni, Anopheles stephensi, and anopheles gambiae mosquitoes were readily infected by feeding on the monkeys and by membrane feeding on diluted blood. Monkey-to-monkey transmission was obtained via the bites of infected mosquitoes and the intravenous injection of sporozoites dissected from salivary glands. This parasite is designated as the brazil I/CDC strain of P. vivax.
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