Cases reported "Mandibular Diseases"

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1/12. Malignant spindle cell tumor arising in the mandible of a patient with florid osseous dysplasia.

    Florid osseous dysplasia is a non-neoplastic condition of the alveolar processes of the jaws characterized by the replacement of multiple foci of bone by fibrous connective tissue, accompanied by gradual deposition of cementum, bone, or both. The lesions are not associated with inflammatory diseases of the dental pulp or periodontal tissues. In fully developed florid osseous dysplasia, there are multiple lobulated masses in the alveolar bone bilaterally in the mandible and sometimes in the maxilla. This is the first report of a malignancy originating within the jaws of a patient with florid osseous dysplasia. A spindle cell malignancy was diagnosed in the mandible of a 54-year-old black woman whose jaw was affected by florid osseous dysplasia bilaterally. Despite extensive surgery and radiotherapy, the patient died 20 months after diagnosis of the malignancy.
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2/12. bone resorption of the mandible in progressive systemic sclerosis.

    Five of 16 patients with progressive systemic sclerosis were found to have bone resorption at the angle of the mandible. This finding appears to be closely related to the tightness of the skin of the face, atrophy of the masseter and pterygoid muscles, small size of the oral orifice, and a significantly high frequency in blacks. The mandible must therefore be added to the list of those bones that can be resorbed in progressive systemic sclerosis.
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3/12. AAOMP case challenge: hemorrhagic gingival mass.

    This 24-year old black female presented with a chief complaint of this gingival mass. She states she first noticed the lesion about three months ago and it has gotten progressively larger. What is your diagnosis?
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4/12. Focal cemento-osseous dysplasia involving a mandibular lateral incisor.

    AIM: To report a case of focal cemento-osseous dysplasia (FCOD) affecting a single tooth misdiagnosed as an inflammatory periapical lesion.SUMMARY: The patient, a black 47-year-old woman complained of pain affecting the right side of the mandible. Routine X-ray examination discovered a periapical radiolucency on the mandibular left lateral incisor (tooth 32), which was otherwise normal and not carious. As the response of this tooth to a vitality test was doubtful, the lesion was diagnosed as a periapical granuloma or cyst secondary to pulpal necrosis. Endodontic treatment and curettage of the periapical lesion were performed, and histological examination of the curettage material revealed a localized osseous dysplasia. KEY learning POINTS: FCOD may rarely affect only one tooth, resembling a periapical granuloma or cyst. Careful diagnosis is of paramount importance in cases of questionable periapical lesions affecting normal-looking teeth, before beginning treatment. FCOD generally requires no treatment. biopsy is warranted in case of doubt.
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5/12. In vivo tetracycline labeling of bone: an intraoperative aid in the surgical therapy of osteoradionecrosis of the mandible.

    In this technical approach, we demonstrate that preoperative tetracycline administration helps distinguish between viable and necrotic bone in osteoradionecrosis (ORN) during surgery by exciting tetracycline fluorescence by black light. The difficult aspect of the operative approach lies in the decision of the extent of the debridement in order to prevent an iatrogenic fracture or progression of ORN. With this technique, vital bone, in contrast to necrotic bone, showed detectable fluorescence. Therefore, tetracycline fluorescence labeling may be used in attempts to facilitate the intraoperative decision making in the surgical therapy of osteoradionecrosis.
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6/12. Aureobasidium infection of the jaw.

    A 32-yr-old white North American male resident of norway presented with an asymptomatic radiolucency first identified 3 yr after the removal of an impacted mandibular right third molar in Southern california 16 yr previously. Surgical exploration revealed an intraosseous cavity filled with a black, homogeneous, gelatinous substance thought to be foreign material, but which was diagnosed histologically as containing black yeasts. Cultivation of a microbiologic sample for 6 wk grew black yeast-like colonies. The yeast isolate was identified as an Aureobasidium species different from the typical A. pullulans. A blood sample was negative with regard to antibodies both with double diffusion technique and ELISA. Also, examination with respect to dermatologic manifestations gave negative results. Flucytocin 10 g/d was administered systemically for 30 d. Six months postoperatively bone regeneration was satisfactory radiologically.
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7/12. Melanin in a dentigerous cyst and associated adenomatoid odontogenic tumor.

    The authors report on a case of dentigerous cyst associated with odontogenic adenomatoid tumor in an 8-year-old black Nigerian boy. Both the cyst and the tumor contained melanocytes and melanin-laden epithelial cells. To their knowledge this is the first reported case of melanotic follicular cyst and adenomatoid tumor. A review of the literature revealed that melanin is rarely found in odontogenic lesions. Since the neural crest influence on the development of odontogenic tissues is well established, the occurrence of melanocytes in these tissues is not surprising. A racial predisposition may be present; black patients predominated in the 15 reported cases of melanotic odontogenic lesions.
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8/12. dentigerous cyst with mural ameloblastoma.

    A case of a 14-year-old black girl with a lesion that appeared to be a dentigerous cyst is presented. Radiographic appearance, findings of a bone scan and biopsy by aspiration are discussed. Histologic findings showed that the lesion was an ameloblastoma that is believed to have arisen from the dentigerous cyst wall.
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9/12. Multiple osteosclerotic masses of the jaw.

    Florid osseous dysplasia is a peculiar reactive or developmental bone disease that is known to appear only in the jaws. It has an inexplicable decided predilection for occurrence in middle-aged, black women. Extent of the disease may vary from a few isolated periapical lesions to diffuse involvement of the mandibular and maxillary alveolar processes. Radiographically, it is characterized by multiquadrant, globular, radiolucent-radiopaque lesions. Histopathologically, it is a benign fibro-osseous lesion that must be differentiated from other benign fibro-osseous lesions such as fibrous dysplasia, ossifying fibroma, Paget's disease, and sclerosing osteomyelitis on the basis of combined clinical, radiographic, and histological features. Correctly identifying this disease is important because it requires no treatment unless a secondary osteomyelitis develops. Sequestrae and osteomyelitis are complications arising when teeth are removed and removable dental prostheses are supported by diseased bone.
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10/12. Myospherulosis of the alveolus secondary to the use of Terra-Cortril and Gelfoam. Report of a case.

    Myospherulosis is a recently discovered disease apparently caused by the placement of mineral oil- or petrolatum-based products into various tissues. Terra-Cortril (a tetracycline/steroid ointment in a petrolatum base) on Gelfoam has been placed in the sockets of surgically removed third molars in an attempt to eliminate the occurrence of dry sockets. The case report presented here documents the radiographic progress of the disease for 6 years, showing an attempt by the bone to repair itself. A surgical procedure was performed to remove the affected tissue, and photographs were taken to illustrate the clinical appearance of the disease. The specimen consisted of a black, tarlike material which was completely encased in bone. Histologic examination was consistent with a diagnosis of myospherulosis.
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