1/284. Mandibular metastasis in a patient with endometrial cancer.Gynecologic cancers metastatic to bone are a rare entity, and a metastasis to the mandible at initial presentation is even more infrequently seen. We present a case of a 71-year-old woman with stage IV endometrial cancer with a metastasis to the mandible, with no other sites of distal spread apparent. The endometrial tumor was a FIGO grade III adenocarcinoma. The pathologic evaluation of the mandibular lesion revealed poorly differentiated adenocarcinoma with focal squamous differentiation. She was treated with a total abdominal hysterectomy and bilateral salpingo-oophorectomy, radiation therapy to the mandible, and chemotherapy consisting of Taxol and carboplatin for six cycles. She had a complete response, but 10 months after the original diagnosis developed spinal cord compression and progressive disease in the pelvis. patients in good clinical condition with a single bone metastasis should be treated aggressively, as survival can be extended.- - - - - - - - - - ranking = 1keywords = carcinoma (Clic here for more details about this article) |
2/284. Metastasis of thyroid carcinoma to the mandible. Case report.Metastatic tumours to the jaw bones are uncommon. The incidence of jaw bone metastasis is difficult to assess accurately since the usual method to determine the distribution of a metastatic tumour has been by a radiographic skeletal survey in which the jaws are rarely included. At times, metastatic lesions of the orofacial region may be the first evidence of dissemination of a known tumour from its primary site. A case of metastatic follicular carcinoma of the thyroid to the mandible is presented. The present case emphasizes the importance of considering metastasis in the differential diagnosis of a radiolucent lesion in the mandible in a patient with a history of any malignant disease.- - - - - - - - - - ranking = 2.5keywords = carcinoma (Clic here for more details about this article) |
3/284. Follicular carcinoma in ectopic thyroid gland. A case report.Ectopic thyroid rest can be seen anywhere along the path of descent of the gland. The most ectopic thyroid tissue is a thyroglossal duct cyst associated with normal thyroid gland. Sublingual location is less common than a lingual ectopia. True malignant transformation in ectopic thyroid tissue is extremely rare. Such a malignancy is virtually always diagnosed only after surgical excision of the lesion at pathological examination. This report discusses a case of ectopic thyroid follicular carcinoma in the right submandibular region in the absence of orthotopic thyroid, discovered by chance after the surgical excision performed for a preoperative ultrasonically and cytologically misdiagnosed submandibular gland adenocystic carcinoma. The possible aetiology of such an unusual anatomical relationship is discussed as well as the importance of thyroid scanning, ultrasound and/or CT in neck lumps.- - - - - - - - - - ranking = 3keywords = carcinoma (Clic here for more details about this article) |
4/284. A case of central carcinoma of the mandible arising from a recurrent odontogenic keratocyst: delineation of surgical margins and reconstruction with bilateral rectus abdominis myocutaneous free flaps.A case of central carcinoma of the mandible arising from a recurrent odontogenic keratocyst is reported. A 38-year-old man was admitted to the Tokai University Hospital due to postoperative infection of a recurrent odontogenic keratocyst of the left mandible. He had had a cystectomy for an odontogenic keratocyst 4 years ago. The lesion revealed bony destruction of the mandible with worm-eating shaped margins with extension to the facial skin. A biopsy specimen revealed squamous cell carcinoma. The mandible was resected with facial skin and the sublingual space was dissected to preserve the lingual nerve. The oral and the facial resections were reconstructed with a titanium plate and bilateral rectus abdominis myocutaneous free flaps. The plate was removed due to infection around the margins and readjustment of the flaps was conducted 5 months after the surgery. He has not had a local relapse, metastasis, or incisional hernia for 8 months following surgery. Good occlusion has been attained by the residual mandible, and he is able to eat without any problems.- - - - - - - - - - ranking = 3keywords = carcinoma (Clic here for more details about this article) |
5/284. Metastatic thyroid carcinoma of the mandibule.A case of metastatic papillary carcinoma to the mandible is presented. Though relatively rare, metastatic tumours of the mandible should be included in the differential diagnosis of the tumours in the parotid region. For the primary site; being in the cervicofacial region, the thyroid gland must be considered by the head and neck surgeon.- - - - - - - - - - ranking = 2.5keywords = carcinoma (Clic here for more details about this article) |
6/284. Squamous cell carcinoma arising in the epithelial lining of a dentigerous cyst.The dentigerous cyst is a common oral lesion arising as a developmental anomaly during amelogenesis. In rare instances, the epithelial lining of these cysts may give rise to squamous cell carcinoma (SCC). Fewer than 50 cases of this rare entity have been reported in the world literature to date. We present an additional case of SCC arising in a dentigerous cyst with a rationale for our treatment approach. In addition, we offer a review of the literature and a review of the clinical, histologic, and radiographic findings associated with this finding. We discuss epidemiologic data and treatment options.- - - - - - - - - - ranking = 2.5keywords = carcinoma (Clic here for more details about this article) |
7/284. Odontogenic ghost cell carcinoma: report of four new cases and review of the literature.Only 12 odontogenic ghost cell carcinomas (OGCC) have been reported in the English language literature to date. This article reports four additional cases of this rare odontogenic tumour and examines them in relation to those previously described. Judging from the number of published cases, the OGCC is more prevalent in Asians than other racial groups, occurs more often in the maxilla than the mandible, and is slightly more common in males than females. Histologically, elements of a benign calcifying odontogenic cyst (COC) can be identified in all the malignant variants, either separated or admixed with the malignant epithelial component. The latter can consist of either small basaloid cells or large epithelial cells. Despite the differing histological presentations, the biological behavior of the tumour is unpredictable, with some cases characterized by relatively indolent growth and others by a locally aggressive and potentially fatal course. The tumour apparently arises most often from malignant transformation of a preexisting benign COC, although it may also develop from other odontogenic tumours.- - - - - - - - - - ranking = 2.5keywords = carcinoma (Clic here for more details about this article) |
8/284. Progression of maxillofacial squamous cell carcinoma evaluated using computer graphics with spiral computed tomography.This report describes the appearance of maxillofacial squamous cell carcinoma in multiplanar (MPR) and three-dimensional (3D) images reconstructed from spiral CT using computer graphics and the importance of the computer software tools in permitting better visualization of the lesion. Two oral and maxillofacial radiologists and one neuroradiologist analysed the images. The usefulness of interactive reconstruction in the diagnosis, surgical planning and treatment evaluation, especially in the localization of the extent of these maxillofacial tumors, was demonstrated. Spiral CT-based computer graphics for displaying MPR and 3D images are an important adjunct in the evaluation of squamous cell carcinoma.- - - - - - - - - - ranking = 3keywords = carcinoma (Clic here for more details about this article) |
9/284. Large cell, epithelioid, telangiectatic osteoblastoma: a unique pseudosarcomatous variant of osteoblastoma.A previously undescribed large-cell, epithelioid, and aneurysmal variant of osteoblastoma with minimal osteoid-production--simulating telangiectatic osteosarcoma, epithelioid angiosarcoma, and metastatic carcinoma is reported. The tumor occurred in the mandible of a 14-year-old girl. The light microscopic, immunohistochemical, ultrastructural, cell proliferation, and dna-ploidy studies, as well as the 7-year disease-free follow-up period all indicate a benign osteoblastic tumor. Cytogenetically, the tumor had a pseudodiploid karyotype, distinguished by a complex t(1;5;17;22) and a terminal 1q deletion. Recognition of this unique, pseudomalignant variant of osteoblastoma is important to avoid an erroneous diagnosis of malignancy.- - - - - - - - - - ranking = 0.5keywords = carcinoma (Clic here for more details about this article) |
10/284. Primary intraosseous carcinoma of the mandible with probable origin from reduced enamel epithelium.This report describes a case of primary intraosseous carcinoma (PIOC) arising de novo in the mandible. The patient was a 74-year-old woman and an early PIOC was found incidentally during histopathological examination of the pericoronal tissue obtained at extraction of a deeply impacted third molar. The curetted soft tissues consisted of a microinvasive, keratinizing squamous cell carcinoma with scattered foci of carcinoma cells showing calcification; stromal osseous metaplasia was also observed. After additional treatment, the patient has remained free of disease for 2 years. Since the tumor was completely enclosed in the bone, the only identifiable source of the present PIOC is the reduced enamel epithelium. Despite its rarity, this case emphasizes the importance of careful histologic examination of all apparently innocuous dental follicles that are removed surgically.- - - - - - - - - - ranking = 3.5keywords = carcinoma (Clic here for more details about this article) |
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